Molecular Mechanisms of Healthy Aging: The Role of Caloric Restriction, Intermittent Fasting, Mediterranean Diet, and Ketogenic Diet—A Scoping Review

Nutrients, Journal Year: 2024, Volume and Issue: 16(17), P. 2878 - 2878

Published: Aug. 28, 2024

As the population ages, promoting healthy aging through targeted interventions becomes increasingly crucial. Growing evidence suggests that dietary can significantly impact this process by modulating fundamental molecular pathways. This review focuses on potential of strategies in and mechanisms which specific nutrients patterns influence key pathways involved cellular repair, inflammation, metabolic regulation. Caloric restriction, intermittent fasting, Mediterranean diet, as well ketogenic diet showed promising effects aging, possibly mTORC1 AMPK, an insulin signaling pathway. By understanding intricate interplay between pathways, we develop personalized not only prevent age-related diseases, but also promote overall health well-being throughout process.

Language: Английский

Strategies for preventing bone loss in populations with insufficient calcium and vitamin D intake

Nutrition Research and Practice, Journal Year: 2025, Volume and Issue: 19(2), P. 155 - 155

Published: Jan. 1, 2025

Calcium and vitamin D are essential nutrients for maintaining skeletal health, yet deficiencies in these particularly widespread regions such as Asia Africa. Inadequate intake of areas has been associated with diminished bone integrity a rising incidence osteoporosis. This review examines the underlying mechanisms loss driven by calcium deficiencies, emphasizing their crucial roles metabolism. It also presents strategies to improve nutrient intake, fortification staple foods supplementation, along lifestyle modifications including increased physical activity, sun exposure, dietary education, prevent effectively. Special consideration is given vulnerable populations, older adults, individuals limited those restrictions, who at higher risk deficiency. The further evaluates public health strategies, government-initiated educational programs, measures tackling deficiencies. Lastly, it explores future avenues addressing potential role digital tools, personalized nutrition, innovative policies alleviate global burden bone-related diseases.

Language: Английский