The Effect of Virotherapy, Chemotherapy, and Immunotherapy to Immune System: Mathematical Modelling Approach DOI Creative Commons
Aminatus Sa’adah,

Prihantini Prihantini,

Bidayatul Masulah

et al.

Kubik Jurnal Publikasi Ilmiah Matematika, Journal Year: 2023, Volume and Issue: 8(2), P. 129 - 140

Published: Nov. 27, 2023

Medical research and therapeutic interventions continue to evolve, one interesting area of study is the complex interaction among virotherapy, chemotherapy, immune system. Each treatment has its own advantages disadvantages. In this study, a mathematical model was developed describe how system, tumor cells, normal cells interact when all three types therapy are used treat cancer patients. To determine effectiveness various treatments, numerical simulations eight different strategies were performed. These measured much concentration decreased as result treatment. Based on performed, application provided greatest reduction (99%) in tumour but also significant (68%) body.

Language: Английский

A Mathematical Perspective on the Influence of Allee Effects in Oncolytic Virotherapy DOI Creative Commons
Eymard Hernández–López, Jin Wang

Mathematics, Journal Year: 2025, Volume and Issue: 13(5), P. 744 - 744

Published: Feb. 25, 2025

This article is concerned with the mathematical modeling of cancer virotherapy, emphasizing impact Allee effects on tumor cell growth. We propose a framework that describes complex interaction between cells and oncolytic viruses. The efficacy this therapy against mathematically investigated. analysis involves linear logistic growth scenarios coupled different effects, including weak, strong, hyper forms. Critical points are identified, their existence stability analyzed using dynamical system theories bifurcation techniques. Also, diagrams numerical simulations utilized to verify extend analytical results. It observed significantly influence conditions necessary for control eradication.

Language: Английский

Citations

0

On a new version of bicomplex Mittag-Leffler functions and their applications in fractional kinetic equations DOI
Ahmed Bakhet, Mohra Zayed, Mohammed A. Saleem

et al.

Alexandria Engineering Journal, Journal Year: 2025, Volume and Issue: 125, P. 409 - 423

Published: April 22, 2025

Language: Английский

Citations

0

A next-generation dynamic programming language Julia: Its features and applications in biological science DOI Creative Commons
Soumen Pal, Manojit Bhattacharya,

Snehasish Dash

et al.

Journal of Advanced Research, Journal Year: 2023, Volume and Issue: 64, P. 143 - 154

Published: Nov. 21, 2023

The advent of Julia as a sophisticated and dynamic programming language in 2012 represented significant milestone computational programming, mathematical analysis, statistical modeling. Having reached its stable release version 1.9.0 on May 7, 2023, has developed into powerful versatile instrument. Despite potential widespread adoption across various scientific technical domains, it can be utilized within biological sciences. Aim Review This comprehensive review aims to address this particular knowledge gap offer thorough examination Julia's fundamental characteristics applications biology. Key concepts the focuses research science. equip researchers with tools utilize capabilities science effectively demonstrate gap. It paves way for innovative solutions discoveries rapidly evolving field. encompasses an analysis characteristics, packages, performance compared languages initial part discusses key features Julia, such interactive nature, fast processing speed, ease expression manipulation, user-friendly syntax, code readability, strong support multiple dispatch, advanced type system. also explores data visualization, machine learning, algorithms, making suitable applications. next section emphasizes importance using research, highlighting seamless integration studies biology, bioinformatics. compares other commonly used through benchmarking analysis. Additionally, provides insights future directions challenges

Language: Английский

Citations

2

The Effect of Virotherapy, Chemotherapy, and Immunotherapy to Immune System: Mathematical Modelling Approach DOI Creative Commons
Aminatus Sa’adah,

Prihantini Prihantini,

Bidayatul Masulah

et al.

Kubik Jurnal Publikasi Ilmiah Matematika, Journal Year: 2023, Volume and Issue: 8(2), P. 129 - 140

Published: Nov. 27, 2023

Medical research and therapeutic interventions continue to evolve, one interesting area of study is the complex interaction among virotherapy, chemotherapy, immune system. Each treatment has its own advantages disadvantages. In this study, a mathematical model was developed describe how system, tumor cells, normal cells interact when all three types therapy are used treat cancer patients. To determine effectiveness various treatments, numerical simulations eight different strategies were performed. These measured much concentration decreased as result treatment. Based on performed, application provided greatest reduction (99%) in tumour but also significant (68%) body.

Language: Английский

Citations

0