Factors associated with male recruitment in a multi-site randomized behavioral clinical trial targeting the metabolic syndrome: analysis of screening and recruitment data from the ELM trial DOI Creative Commons
Chen Yeh, Melissa M. Crane, Bryce T. Daniels

et al.

Trials, Journal Year: 2024, Volume and Issue: 25(1)

Published: Dec. 21, 2024

Males are underrepresented in behavioral clinical trials of lifestyle. The aim this exploratory study was to investigate factors associated with trial interest males at different stages recruitment and overall, into a multi-site targeting lifestyle change remission the metabolic syndrome. Similar analyses were performed for female participation uniqueness or consistency findings males. Data collected various an ongoing used. A series logistic regressions compared respondents who moved forward next step screening process versus those did not. These stratified by sex. chi-squared test used directly compare proportions men women chose advance step. showed more likely be self-aware their current health risk. Comparison females that tended lose earlier (58.3% vs. 66.5% attended in-person information session, p < 0.001), but proportion among demonstrated initial similar women. Efforts increase male enrollment will benefit from focus on early recruitment, aiming potential participants' levels awareness As differ reasons they choose participate trial, should tailored sex maximize participation. ClinicalTrials.gov NCT04036006. Registered July 29, 2019. https://clinicaltrials.gov/study/NCT04036006

Language: Английский

The Association between Use of Tobacco, Alcohol, or Cannabis and Metabolic Syndrome DOI

Betty M. Drees,

Pavani Chilamkuri,

Bong Nguyen

et al.

American Journal of Health Behavior, Journal Year: 2025, Volume and Issue: 49(1), P. 52 - 63

Published: Jan. 31, 2025

Objectives: In this study, we describe the relationship between metabolic syndrome (MetS) components and tobacco use other behavioral socio-economic characteristics. Methods: We collected demographic, anthropometric, bioclinical data on 961 individuals at risk of MetS. categorized frequency product substances (alcohol cannabis) as never, occasional, regular. used regression models to assess substance with MetS Results: Tobacco differed significantly by age, gender, race, education, employment status. Regular was associated higher blood pressure (131/85 in regular users compared 127/82 never users; p < .05). alcohol levels glucose (p = .002) a lower likelihood meeting criteria based low HDL .017). cannabis waist circumference .006) level .027). Conclusion: Use or impacts factors. This impact should be considered when assessing cardiovascular disease making recommendations for lifestyle changes.

Language: Английский

Citations

0
Type 2 Diabetes Mellitus and Cardiometabolic Prospects: A Rapid Narrative Review DOI Open Access

Kona Chowdhury,

Susmita Sinha, Rahnuma Ahmad

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: July 30, 2024

Cardiometabolic syndrome (CMS), type 2 diabetes mellitus (T2DM), and cardiovascular diseases are among the major altruists to international liability of disease. The lifestyle dietary changes attributable economic growth have resulted in an epidemiological transition towards non-communicable (NCDs) as leading causes death. Low- middle-income countries (LMICs) bear a more substantial disease burden due limited healthcare sector capacities address rapidly growing number chronic patients. purpose this narrative review paper was explore interrelationships between CMS, T2DM, impairments context NCDs, well preventative control interventions. role insulin resistance, hyperglycemia, dyslipidemia pathogenesis T2DM development severe highlighted. This elaborated on pivotal modifications, such healthy diets physical activity, cornerstones addressing epidemics metabolic diseases. Foods high calories, refined sugar, red meat, processed ready-to-eat meals were associated with amplified risk CMS T2DM. In contrast, based fruits, legumes, vegetables, whole grain, home-cooked foods demonstrated protective effects against Additionally, psychological behavioral approach highlighted, especially regarding its impact patient empowerment patient-centered therapeutic

Language: Английский

Citations

1
Exploratory analysis of the variable response to an intensive lifestyle change program for metabolic syndrome DOI Creative Commons
Scott B. Maitland, Paula Brauer, David M. Mutch

et al.

BMC Primary Care, Journal Year: 2024, Volume and Issue: 25(1)

Published: Oct. 1, 2024

Language: Английский

Citations

1
Mindfulness-Based Interventions for Metabolic Syndrome in The Elderly: A Review of Evidence on Psychological and Physiological Outcomes DOI Creative Commons

Pradhiba SPM,

Thephilah Cathrine R,

P Jayanthi

et al.

National Journal of Community Medicine, Journal Year: 2024, Volume and Issue: 15(07), P. 606 - 614

Published: July 1, 2024

Background: Metabolic syndrome poses a significant health challenge in the elderly, affecting both psychological and physiological aspects. The application of mindfulness treating lifestyle variables linked to risk cardiovascular disease shows promise improving self-awareness, mood regulation, attention control. In addition lowering stress, anxiety, depression therapies have potential improve glycemic management. This study aims investigate efficacy mindfulness-based interventions addressing this complex issue. Methods: Cochrane Library, Embase, PubMed/MEDLINE electronic databases were searched by author find pertinent systematic reviews meta-analyses. Results: A summary available research review explores impact on elderly individuals with metabolic from years 2011-2023. Examining outcomes, focuses depression, quality life, key indicators such as BMI, cholesterol levels, blood sugar. Conclusion: Findings shed light benefits practices mental well-being positively influencing parameters population. To fully understand biological impacts human processes, more investigation is required.

Language: Английский

Citations

0
Food Security and Cardio-Metabolic Risk in Individuals with Metabolic Syndrome DOI Open Access
Bong Nguyen, Barbara Lohse, Lynda H. Powell

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2024, Volume and Issue: 22(1), P. 28 - 28

Published: Dec. 29, 2024

This study assessed the association of food security with potential cardio-metabolic risk factors among persons metabolic syndrome (MetS). Data were derived from baseline data a randomized controlled lifestyle intervention trial for individuals MetS. Household security, fruit and vegetable intake, perceived environment, stress collected using validated questionnaires. Cardio-metabolic measures standardized procedures included body mass index, waist circumference, blood pressure, glucose, HbA1c, lipids. Regression models adjusted demographics, medication use, performed. Of total 664 participants (median age 56), majority female, non-Hispanic White, college-educated, employed. Food insecurity affected 23% (n = 152), 5% 31) experiencing very low security. Food-insecure had significantly higher (p < 0.001), lacked healthy access less likely to consume ≥2 servings vegetables/day 0.003). HbA1c was only measure associated 0.007). The link between elevated levels highlights importance addressing improve health outcomes in MetS population.

Language: Английский

Citations

0
Development of a Predictive Model for Metabolic Syndrome Using Noninvasive Data and its Cardiovascular Disease Risk Assessments: Multicohort Validation Study (Preprint) DOI

Jin-Hyun Park,

Inyong Jeong, Gang-Jee Ko

et al.

Published: Oct. 14, 2024

BACKGROUND Metabolic syndrome is a cluster of metabolic abnormalities, including obesity, hypertension, dyslipidemia, and insulin resistance, that significantly increase the risk cardiovascular disease (CVD) other chronic conditions. Its global prevalence rising, particularly in aging urban populations. Traditional screening methods rely on laboratory tests specialized assessments, which may not be readily accessible routine primary care community settings. Limited resources, time constraints, inconsistent practices hinder early identification intervention. Developing noninvasive scalable predictive model could enhance accessibility improve detection. OBJECTIVE This study aimed to develop validate for using body composition data. Additionally, we evaluated model’s ability predict long-term CVD risk, supporting its application clinical public health settings intervention preventive strategies. METHODS We developed machine learning–based data from two nationally representative cohorts: Korea National Health Nutrition Examination Survey (KNHANES) Korean Genome Epidemiology Study. The was trained dual-energy x-ray absorptiometry KNHANES (2008-2011) validated internally with bioelectrical impedance analysis 2022. External validation conducted Study follow-up datasets. Five learning algorithms were compared, best-performing selected based area under receiver operating characteristic curve. Cox proportional hazards regression used assess risk. RESULTS demonstrated strong performance across cohorts. Area curve values prediction ranged 0.8338 0.8447 internal validation, 0.8066 0.8138 external 1, 0.8039 0.8123 2. predictions associated future indicating individuals classified as having had 1.51-fold higher developing (hazard ratio 1.51, 95% CI 1.32-1.73; <i>P</i>&lt;.001). highlights potential utility this guiding interventions. CONCLUSIONS diverse By enabling without tests, enhances large-scale screenings. supports proactive strategies, potentially reducing burden cardiometabolic diseases. Further research should refine additional factors broader population maximize impact.

Language: Английский

Citations

0
Factors associated with male recruitment in a multi-site randomized behavioral clinical trial targeting the metabolic syndrome: analysis of screening and recruitment data from the ELM trial DOI Creative Commons
Chen Yeh, Melissa M. Crane, Bryce T. Daniels

et al.

Trials, Journal Year: 2024, Volume and Issue: 25(1)

Published: Dec. 21, 2024

Males are underrepresented in behavioral clinical trials of lifestyle. The aim this exploratory study was to investigate factors associated with trial interest males at different stages recruitment and overall, into a multi-site targeting lifestyle change remission the metabolic syndrome. Similar analyses were performed for female participation uniqueness or consistency findings males. Data collected various an ongoing used. A series logistic regressions compared respondents who moved forward next step screening process versus those did not. These stratified by sex. chi-squared test used directly compare proportions men women chose advance step. showed more likely be self-aware their current health risk. Comparison females that tended lose earlier (58.3% vs. 66.5% attended in-person information session, p < 0.001), but proportion among demonstrated initial similar women. Efforts increase male enrollment will benefit from focus on early recruitment, aiming potential participants' levels awareness As differ reasons they choose participate trial, should tailored sex maximize participation. ClinicalTrials.gov NCT04036006. Registered July 29, 2019. https://clinicaltrials.gov/study/NCT04036006

Language: Английский

Citations

0