The Neuropathological Impacts of COVID-19: Challenges and Alternative Treatment Options for Alzheimer’s Like Brain Changes on Severely SARS-CoV-2 Infected Patients

American Journal of Alzheimer s Disease & Other Dementias®, Journal Year: 2023, Volume and Issue: 38

Published: Oct. 1, 2023

Recently, some researchers claimed neuropathological changes lead to Alzheimer’s-like brains after severe infection of SARS-CoV-2. Several mechanisms have been postulated on how SARS-CoV-2 neurological damage leads Alzheimer's disease (AD) development. Neurobiochemical during may significantly induce in severely COVID-19 infected people. The immune system is also compromised while by this novel coronavirus. However, recent studies are insufficient conclude the relationship between and COVID-19. This review demonstrates possible pathways induced virus AD patients or leading patients. Therefore, study delineates challenges for mechanism actions natural compounds alternative treatments overcome those. Furthermore, animal a large cohort survivors who showed neuroinflammation augment research discover

Language: Английский

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Saponins: A class of bioactive natural products with wide applications in human health

Studies in natural products chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 185 - 233

Published: Jan. 1, 2024

Language: Английский

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Inhibition of blood pressure elevation in GABA‐enriched Hidakakombu fermented with Lactiplantibacillus plantarum 002 protected addition of trehalose

International Journal of Food Science & Technology, Journal Year: 2024, Volume and Issue: 59(3), P. 1572 - 1579

Published: Jan. 15, 2024

Summary Hidakakombu ( Saccharina angustata ) is an edible brown alga produced in the Hidaka region of Hokkaido. It graded at time processing, and low‐grade products have a low market value. New ways to utilise are needed increase producer profits. In this study, was fermented with Lactiplantibacillus plantarum 002 determine its functional properties. Fermentation increased γ‐aminobutyric acid (GABA) content. The addition trehalose L. inhibited decrease number 002, while maintaining high level GABA. trehalose‐supplemented remained viable simulated gastric juice grew intestinal juice. 002‐fermented has antihypertensive function that attributed protected enhanced freeze‐drying digestive tolerance.

Language: Английский

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Research Progress of Stem Cell Exosomes in Alzheimer’s Disease

Bioprocess, Journal Year: 2023, Volume and Issue: 13(02), P. 91 - 97

Published: Jan. 1, 2023

Language: Английский

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Relação entre doenças inflamatórias intestinais atividade física e doenças neurodegenerativas

Revista Cereus, Journal Year: 2023, Volume and Issue: 15(4)

Published: Jan. 1, 2023

A pesquisa explorou a relação entre disbiose intestinal e atividade física, investigando associações com doenças neurológicas. Os documentos foram extraídos das bases de dados ferramentas Scielo, Pubmed Web of Science Search acordo as palavras-chave definidas pelo DeCS/MeSH. Utilizou revisões sistemáticas, meta-análise para garantir qualidade metodológica. Para análise qualitativa foi seguido normas diretrizes denominado RATS (Relevância, Adequação, Transparência Solidez) contextual realizada através do software Rayyan - AI Powered Tool for Systematic Literature Reviews cegas pelos autores. Na contextualização os pesquisadores elucidou alterações na composição função da microbiota podem estar envolvidas no desenvolvimento progressão sistema nervoso central; resultados indicam significativas inflamatórias intestinais é um risco neurodegenerativas o método genômica demonstrou ser mais significativo fornecem suporte à hipótese que processos inflamatórios crônicos desempenham condições doença Alzheimer distúrbios trato gastrointestinal. Concluiu-se afeta saúde humana, física dieta equilibrada prevenir neurológicas, incluindo Alzheimer. Entretanto, pesquisas são necessárias entender completamente essa interação complexa

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