Considering the nutritional benefits and health implications of red meat in the era of meatless initiatives

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: Jan. 27, 2025

Driven by perceived health and environmental benefits, initiatives to remove red meat from recommended eating patterns are increasingly being implemented in United States institutions, including schools hospitals. While these efforts aim address important issues, they may inadvertently lead unintended consequences, particularly regarding essential nutrient intake for certain populations. This perspective considers the nutritional value of meat, examines its potential highlights risks when is reduced or eliminated. Red a nutrient-dense food that provides highly bioavailable protein several micronutrients often lacking diet, iron, zinc, vitamin B 12 . These nutrients can be limited absent many plant-source foods as well some animal-source foods. meat’s micronutrient profile especially valuable young children women reproductive age, pregnant women. In addition, density beneficial individuals managing obesity older adults at risk sarcopenia. Many epidemiological studies suggest associations between excessive consumption increased chronic diseases, but this evidence does not conclusively implicate development progression disease. The implications reducing must balanced against low certainty used discourage making dietary recommendations.

Language: Английский

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Iron Deficiency in Adults

JAMA, Journal Year: 2025, Volume and Issue: unknown

Published: March 30, 2025

Absolute iron deficiency, defined as low stores with or without anemia, affects approximately 2 billion people worldwide and 14% of adults in the US. Iron-deficiency hemoglobin due to stores, 1.2 worldwide, including 10 million deficiency progresses from iron-deficiency anemia. Individuals nonanemic anemia may be asymptomatic experience fatigue, irritability, depression, difficulty concentrating, restless legs syndrome (32%-40%), pica (40%-50%), dyspnea, lightheadedness, exercise intolerance, worsening heart failure (HF). Symptom prevalences vary depending on age, comorbidities (eg, chronic kidney disease [CKD], HF), severity rate development deficiency. The most common causes are bleeding (menstrual, gastrointestinal), impaired absorption (atrophic gastritis, celiac disease, bariatric surgical procedures), inadequate dietary intake, pregnancy. In high-income countries, 38% nonpregnant, reproductive-age women have about 13% During third trimester pregnancy, up 84% pregnant women, based data countries. Additional risk factors include use nonsteroidal anti-inflammatory drugs, inflammatory bowel (IBD [13%-90%]), other conditions, such CKD (24%-85%), HF (37%-61%), cancer (18%-82%). Testing for is indicated patients and/or symptoms (fatigue, pica, syndrome) should considered those heavy menstrual bleeding, IBD. Iron diagnosed by serum ferritin (typically <30 ng/mL) individuals conditions transferrin saturation (iron/total binding capacity × 100) less than 20%. Causes identified treated. Oral (ferrous sulfate 325 mg/d alternate days) typically first-line therapy. Intravenous oral poor (celiac post-bariatric procedure), (CKD, HF, IBD, cancer), ongoing blood loss, during second trimesters that cause concentrating. Ferritin required diagnosis screening. therapy patients. used who do not tolerate iron, certain (IBD, CKD,

Language: Английский

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Associations between serum trace elements and biological age acceleration in the Chinese elderly: A community-based study investigating the mediating role of inflammatory markers and the moderating effect of physical activity

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: unknown, P. 138273 - 138273

Published: April 1, 2025

Language: Английский

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Cost‐Effectiveness of Ferritin Screening Thresholds for Iron Deficiency in Reproductive‐Age Women

American Journal of Hematology, Journal Year: 2025, Volume and Issue: unknown

Published: April 16, 2025

ABSTRACT Iron deficiency (ID) is a top five leading cause of disability‐adjusted life‐years in women reproductive age around the world. Despite its enormous health burden, no screening guidelines exist for detection and treatment ID age. We sought to determine cost‐effectiveness versus United States. A lifetime simulation was conducted using Markov cohort model under three strategies: (1) screening, (2) at ferritin threshold 15 μg/L, (3) 25 from US system perspective, willingness‐to‐pay $100 000/quality‐adjusted life year (QALY). Epidemiologically informed prevalence estimates sourced National Health Nutrition Examination Survey were employed parameterization. The primary outcome incremental ratio (ICER, $/QALY). Base‐case results strategies accrued $209 700, $210 200, 200 discounted costs 23.6, 24.0, 24.4 QALYs, respectively. Screening μg/L cost‐effective intervention with an ICER $680/QALY (95% credible interval $350–$750/QALY). In dual base‐case analyses examining intravenous rather than oral iron repletion treatment, remained $2300/QALY CI $1800–$3800/QALY). probabilistic sensitivity analyses, 100% 10 000 s order Monte Carlo iterations.

Language: Английский

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The impact of cigarette smoke as a risk factor for hypertension in pregnancy

Jurnal Edukasi Ilmiah Kesehatan, Journal Year: 2024, Volume and Issue: 2(3), P. 94 - 102

Published: Nov. 22, 2024

Introduction: Hypertension in pregnancy is one of the severe complications and leading cause maternal perinatal morbidity mortality. Risk factors for hypertension include various aspects, including exposure to cigarette smoke, which has a detrimental impact on mother fetus. This study aims analyze smoke as risk factor pregnancy. Methods: The design observational analytical research with cross-sectional uses point-time, observation, or data collection methods examine relationship dynamics between factors. dependent variable this prevalence pregnant women. number samples was 128 people using purposive sampling technique. Results: results showed that women who were exposed both active passive, had higher developing compared mothers not exposed. Harmful components such nicotine carbon monoxide, play role raising blood pressure through vasoconstriction mechanisms oxidative stress, aggravate workload heart circulatory system. Conclusions: These findings show need prevention education efforts reduce women, incidence pregnancy, improve health babies. With information, it hoped workers public can be more aware dangers during strive smoke-free environment

Language: Английский

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Finally, a quality prospective study to support a proactive paradigm in anemia of pregnancy

American Journal of Clinical Nutrition, Journal Year: 2024, Volume and Issue: 120(5), P. 997 - 998

Published: Sept. 26, 2024

Language: Английский

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