COVID‐19 and pregnancy: A review of clinical characteristics, obstetric outcomes and vertical transmission

Australian and New Zealand Journal of Obstetrics and Gynaecology, Journal Year: 2020, Volume and Issue: 60(5), P. 640 - 659

Published: Aug. 10, 2020

Abstract Background Since its emergence in December 2019, COVID‐19 has spread to over 210 countries, with an estimated mortality rate of 3–4%. Little is understood about effects during pregnancy. Aims To describe the current understanding illness pregnant women, obstetric outcomes and identify gaps existing knowledge. Methods Medline Ovid, EMBASE, World Health Organization research database Cochrane pregnancy spreadsheet were accessed on 18/4, 18/5 23/5 2020. Articles screened via Preferred Reporting Items for Systematic Reviews Meta‐Analyses guidelines. The following excluded: reviews, opinion pieces, guidelines, articles pertaining solely other viruses, single case reports. Results Sixty included this review. Some participants may have been multiple publications, as admission dates overlap reports from same hospital. However, a total 1287 confirmed SARS‐CoV‐2 positive cases are reported. Where universal testing was undertaken, asymptomatic infection occurred 43.5–92% cases. In cohort studies, severe critical rates approximated those non‐pregnant population. Eight maternal deaths, six neonatal seven stillbirths five miscarriages Nineteen neonates positive, by reverse transcription polymerase chain reaction nasopharyngeal swabs. [Correction added 2 September 2020, after first online publication: number indicated preceding sentence corrected ‘Thirteen’ ‘Nineteen’.] Conclusions screening conducted, often asymptomatic. Severe disease approximate general Vertical transmission possible; however, it unclear whether infected utero , intrapartum or postpartum. Future work should assess risks congenital syndromes adverse perinatal where occurs early mid‐pregnancy.

Language: Английский

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Epidemiology of coronavirus disease 2019 in pregnancy: risk factors and associations with adverse maternal and neonatal outcomes

American Journal of Obstetrics and Gynecology, Journal Year: 2020, Volume and Issue: 224(4), P. 389.e1 - 389.e9

Published: Sept. 25, 2020

BackgroundCoronavirus disease 2019 may be associated with adverse maternal and neonatal outcomes in pregnancy, but there are few controlled data to quantify the magnitude of these risks or characterize epidemiology risk factors.ObjectiveThis study aimed associations coronavirus pregnancy factors.Study DesignWe performed a matched case-control pregnant patients confirmed cases who delivered between 16 41 weeks' gestation from March 11 June 11, 2020. Uninfected women (controls) were on 2:1 ratio based delivery date. Maternal demographic characteristics, symptoms, laboratory evaluations, obstetrical outcomes, clinical management chart abstracted. The primary included (1) composite outcome, defined as preeclampsia, venous thromboembolism, antepartum admission, intensive care unit need for mechanical ventilation, supplemental oxygen, death, (2) respiratory distress syndrome, intraventricular hemorrhage, necrotizing enterocolitis, 5-minute Apgar score <5, persistent category 2 fetal heart rate tracing despite intrauterine resuscitation, death. To exposure mild severe critical unadjusted adjusted analyses using conditional logistic regression (to account matching), matched-pair odds 95% confidence interval 1000 bias-corrected bootstrap resampling effect measure. Associations potential confounders.ResultsA total 61 enrolled during period (mild disease, n=54 [88.5%]; n=6 [9.8%]; n=1 [1.6%]). outcome 3.4 times higher among than controls (18.0% vs 8.2%; ratio, 3.4; interval, 1.2–13.4). 1.7 case group control 13.9%; 1.7; 0.8–4.8). Stratified by severity indicated that morbidity was largely driven phenotype. Major factors black Hispanic race, advanced age, medical comorbidities, admissions related 2019.ConclusionCoronavirus is an increased association primarily 2019. Black obesity, morbidity. Coronavirus factors. This We confounders. A

Language: Английский

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Effect of COVID-19 on Mortality of Pregnant and Postpartum Women: A Systematic Review and Meta-Analysis

Journal of Pregnancy, Journal Year: 2021, Volume and Issue: 2021, P. 1 - 33

Published: March 5, 2021

Based on what is known at this time, pregnant women are an increased risk of severe illness from COVID-19 compared to nonpregnant women. Additionally, with might have adverse pregnancy outcomes. To investigate the effects coronavirus disease 2019 (COVID-19) mortality and postpartum women, we performed a systematic review available published literature pregnancies affected by COVID-19.

Language: Английский

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The Role of Nutrition in COVID-19 Susceptibility and Severity of Disease: A Systematic Review

Journal of Nutrition, Journal Year: 2021, Volume and Issue: 151(7), P. 1854 - 1878

Published: April 19, 2021

Language: Английский

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Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection: The INTERCOVID Multinational Cohort Study

Obstetrical & Gynecological Survey, Journal Year: 2022, Volume and Issue: 77(2), P. 80 - 82

Published: Feb. 1, 2022

(Abstracted from JAMA Pediatr 2021;175:817–826) At the beginning of COVID-19 pandemic, extent risks a COVID infection during pregnancy were unknown. During start there only few studies published comparing outcomes between pregnant women with and without infections.

Language: Английский

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