Metastatic Renal Cell Carcinoma Presenting a Maxillary Mucosal Lesion as a First Visible Sign of Disease: A Case Report and Review of Literature DOI Creative Commons
Umma Habiba, Abu Faem Mohammad Almas Chowdhury, Rizwan Ahmed

et al.

Diagnostics, Journal Year: 2025, Volume and Issue: 15(7), P. 938 - 938

Published: April 7, 2025

Background and Clinical Significance: Renal cell carcinoma (RCC) is the third most common cancer that metastasizes to oral maxillofacial region following breast lung cancers. Metastatic involvement in cavity rare can present as a diagnostic challenge due non-specific clinical features mimic other benign or malignant conditions. The limited information available regarding metastasis of RCC highlights importance recognizing this uncommon presentation. Case Presentation: A 50-year-old female presented with painful swelling buccal palatal mucosa right maxilla progressively enlarged over several months. Initially, lesion was diagnosed clinically pyogenic granuloma. However, given lesion's continued growth unusual presentation, biopsy performed. Histopathological examination confirmed metastatic renal clear-cell (ccRCC), immunohistochemical analysis verifying origin. Further tests, including computed tomography (CT) urogram, chest CT, bone scintigraphy, revealed additional metastases left adrenal gland, lungs, bone. Conclusions: This case notable because first visible sign RCC, making it presentation RCC. underscores thorough history taking, detailed evaluations, considering conditions differential diagnosis swellings. Additionally, reinforces significance routine screenings for early detection undiagnosed cancer. We also updated previous literature review head neck region, covering cases until 2023.

Language: Английский

Metastatic Renal Cell Carcinoma Presenting a Maxillary Mucosal Lesion as a First Visible Sign of Disease: A Case Report and Review of Literature DOI Creative Commons
Umma Habiba, Abu Faem Mohammad Almas Chowdhury, Rizwan Ahmed

et al.

Diagnostics, Journal Year: 2025, Volume and Issue: 15(7), P. 938 - 938

Published: April 7, 2025

Background and Clinical Significance: Renal cell carcinoma (RCC) is the third most common cancer that metastasizes to oral maxillofacial region following breast lung cancers. Metastatic involvement in cavity rare can present as a diagnostic challenge due non-specific clinical features mimic other benign or malignant conditions. The limited information available regarding metastasis of RCC highlights importance recognizing this uncommon presentation. Case Presentation: A 50-year-old female presented with painful swelling buccal palatal mucosa right maxilla progressively enlarged over several months. Initially, lesion was diagnosed clinically pyogenic granuloma. However, given lesion's continued growth unusual presentation, biopsy performed. Histopathological examination confirmed metastatic renal clear-cell (ccRCC), immunohistochemical analysis verifying origin. Further tests, including computed tomography (CT) urogram, chest CT, bone scintigraphy, revealed additional metastases left adrenal gland, lungs, bone. Conclusions: This case notable because first visible sign RCC, making it presentation RCC. underscores thorough history taking, detailed evaluations, considering conditions differential diagnosis swellings. Additionally, reinforces significance routine screenings for early detection undiagnosed cancer. We also updated previous literature review head neck region, covering cases until 2023.

Language: Английский

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