Dietary Pediastrum boryanum microalgal extract improves growth, enhances immunity, and regulates immune-related genes in Nile tilapia DOI Creative Commons

Ahmed H Al-Wakeel,

Samia Elbahnaswy, Engy Risha

et al.

BMC Veterinary Research, Journal Year: 2024, Volume and Issue: 20(1)

Published: July 18, 2024

Abstract Background Identifying alternative sustainable feed sources with high nutritional values is crucial for the future of environmentally and socially responsible aquaculture. In this regard, microalgae have been proven to positive effects on fish health, which overwhelmed our interest in study. Methods Pediastrum boryanum ( P. ) was incorporated into Nile tilapia at concentrations 0, 0.75, 1.5 mg/kg, as control, PbExt 0.75 , groups assess its growth biochemical indices, oxidant/antioxidant activities, immune stress-related gene expression, intestinal morphology. Results After 8 weeks, fed supplemented exhibited significant increases final weight, length, condition factor, body weight gain, specific rate, while spleen-somatic index (SSI) hepatosomatic (HSI) showed no differences compared control group. Dietary supplementation also enhanced IgM levels lysozyme activity, along marked effect markers liver function enzymes (alanine aminotransferase/ALT aspartate aminotransferase/AST) or protein status (total albumin). Furthermore, addition increased activity superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH) enzymes, highlighting antioxidant potential, whereas malondialdehyde (MDA) among groups. Gene expression analysis revealed that tumor necrosis factor-α TNF-α) interleukin-10 IL-10) transforming factor-β1 TGF-β1) notably containing feed, difference observed hepatic Heat Shock Protein 70 HSP70) mRNA expression. Histopathological examination adverse liver, spleen, tissues. Villous height villous surface area were group, suggesting improved integrity nutrient absorption. Conclusion can potentially improve performance, response, status, health tilapia, making it a promising candidate

Language: Английский

Dietary Pediastrum boryanum microalgal extract improves growth, enhances immunity, and regulates immune-related genes in Nile tilapia DOI Creative Commons

Ahmed H Al-Wakeel,

Samia Elbahnaswy, Engy Risha

et al.

BMC Veterinary Research, Journal Year: 2024, Volume and Issue: 20(1)

Published: July 18, 2024

Abstract Background Identifying alternative sustainable feed sources with high nutritional values is crucial for the future of environmentally and socially responsible aquaculture. In this regard, microalgae have been proven to positive effects on fish health, which overwhelmed our interest in study. Methods Pediastrum boryanum ( P. ) was incorporated into Nile tilapia at concentrations 0, 0.75, 1.5 mg/kg, as control, PbExt 0.75 , groups assess its growth biochemical indices, oxidant/antioxidant activities, immune stress-related gene expression, intestinal morphology. Results After 8 weeks, fed supplemented exhibited significant increases final weight, length, condition factor, body weight gain, specific rate, while spleen-somatic index (SSI) hepatosomatic (HSI) showed no differences compared control group. Dietary supplementation also enhanced IgM levels lysozyme activity, along marked effect markers liver function enzymes (alanine aminotransferase/ALT aspartate aminotransferase/AST) or protein status (total albumin). Furthermore, addition increased activity superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH) enzymes, highlighting antioxidant potential, whereas malondialdehyde (MDA) among groups. Gene expression analysis revealed that tumor necrosis factor-α TNF-α) interleukin-10 IL-10) transforming factor-β1 TGF-β1) notably containing feed, difference observed hepatic Heat Shock Protein 70 HSP70) mRNA expression. Histopathological examination adverse liver, spleen, tissues. Villous height villous surface area were group, suggesting improved integrity nutrient absorption. Conclusion can potentially improve performance, response, status, health tilapia, making it a promising candidate

Language: Английский

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