The American Journal of Medicine, Journal Year: 2024, Volume and Issue: 137(12), P. e242 - e242
Published: Oct. 16, 2024
Language: Английский
Biomarker Research, Journal Year: 2025, Volume and Issue: 13(1)
Published: Jan. 23, 2025
Abstract Background Heart failure (HF) remains a significant public health challenge globally. This study aims to systematically analyze the global HF disease burden from 1990 2021 across temporal, spatial, and demographic dimensions provide evidence for targeted prevention control strategies. Methods Using data Global Burden of Disease (GBD) study, we analyzed through prevalent cases, years lived with disability (YLDs), age-standardized rates per 100,000 population. Temporal trends were evaluated using estimated annual percentage change (EAPC) joinpoint regression analysis. The relationship between Socio-demographic Index (SDI) was explored Pearson correlation analysis, while attribution analysis identified main causes HF. When appropriate, analyses stratified by 5 SDI regions, 21 GBD 204 countries territories, 20 age groups, both sexes. Results prevalence YLDs showed substantial increases 2021, increasing 641.14 676.68 Notably, high-SDI regions exhibited declining since 2019, indicating potential turning point. High-income North America bears heaviest South Asia shows fastest growth rate. level negligible. in males consistently exceeded that females, rising sharply after 60. their attributable proportions were: ischemic heart (34.53%), hypertensive (22.53%), other cardiomyopathies (7.61%), chronic obstructive pulmonary (6.51%), congenital anomalies (5.69%), distribution patterns differing groups regions. Conclusion increased significantly over recent decades, point 2019 marked regional disparities. It is essential prioritize heavy burdens or rapid rates, strengthen management major causes, monitor post-COVID era.
Language: Английский
Citations
0
Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)
Published: April 23, 2025
Frailty is associated with poor outcomes in heart failure (HF). Handgrip strength (HGS) a simple indicator of Physical frailty. We aimed to assess the prognostic value HGS patients under 60 years old acute decompensated HF reduced ejection fraction (HFrEF). In this cross-sectional study, we enrolled 125 HFrEF. was measured using manual dynamometer. The primary outcome in-hospital mortality. Univariate logistic regression analysis performed identify risk factors Receiver operating characteristic (ROC) curve used predictive for mortality rate 16%. Survivors had numerically higher, though not statistically significant, median compared non-survivors (18.8 (IQR: 13.2-25.3) kg vs. 13 11.4-19.5) kg; p = 0.06). showed negative correlation length stay (rho - 0.202, 0.024) and NT-proBNP levels 0.256, 0.004). area ROC overall predicting 0.630 (p 0.043). Lower left ventricular higher were significantly increased odds univariate analysis. handgrip longer hospital levels, demonstrated modest ability predict However, further research necessary establish standardized measurement methods optimal thresholds before can be widely implemented management patient population.
Language: Английский
Citations
0
Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 12
Published: April 29, 2025
Objectives This study aims to integrate the data on effects of a pre-established medical care program hospitalized older adults with chronic heart failure (CHF). Method A comprehensive systematic review incorporating mixed research methodologies was undertaken. Quality assessment conducted using Critical Appraisal Tool developed by Joanna Briggs Institute, adhering PRISMA guidelines for studies. Where appropriate, were synthesized and aggregated meta-analysis or meta-aggregation. Results total 2,825 articles found, which 11 met inclusion criteria. Meta-analysis showed that implementation advance planning (ACP) can significantly increase willingness proportion patients CHF choose receive hospice services during their end-of-life phase. Meta-aggregation ACP intervention has positive impact participants, promotes knowledge understanding, makes them share decision-making families. Conclusion is promising feasible help accurately understand express wishes timely. provides insights empirical evidence improve ACP, valuable guidance reference future clinical practice. Systematic registration https://www.crd.york.ac.uk/PROSPERO/ , PROSPERO, identifier: CRD42024580814.
Language: Английский
Citations
0
Quantitative Imaging in Medicine and Surgery, Journal Year: 2024, Volume and Issue: 14(3), P. 2514 - 2527
Published: March 1, 2024
Background: Heart failure with preserved ejection fraction (HFpEF) is a highly prevalent progressive disease accompanied by poor quality of life, high utilization medical resources, morbidity, and mortality. However, the role left ventricular (LV) systolic dysfunction has yet to be well elaborated despite preservation LV fraction. This study aimed explore diagnostic value speckle-tracking stratified strain combined myocardial work (MW) measurement in evaluating patients HFpEF.
Language: Английский
Citations
1
Stats, Journal Year: 2024, Volume and Issue: 7(3), P. 1066 - 1083
Published: Sept. 23, 2024
Heart failure is a major global health concern, especially in Ethiopia. Numerous studies have analyzed heart data to inform decision-making, but these often struggle with limitations accurately capture death dynamics and account for within-cluster dependence heterogeneity. Addressing limitations, this study aims incorporate analyze estimate survival time identify risk factors affecting patient survival. The data, obtained from 497 patients at Jimma University Medical Center Ethiopia were collected between July 2015 January 2019. Residence was considered as the clustering factor analysis. We employed Bayesian accelerated (AFT), AFT shared gamma frailty models, comparing their performance using Deviance Information Criterion (DIC) Watanabe–Akaike (WAIC). log-normal model had lowest DIC WAIC, well-capturing cluster dependency that attributed unobserved heterogeneity residences. Unlike other methods use Markov-Chain Monte-Carlo (MCMC), we applied Integrated Nested Laplace Approximation (INLA) reduce computational load. found 39.44% of died, while 60.56% censored, median 34 months. Another interesting finding adding into models boosted fitting dataset. Significant reducing included age, chronic kidney disease, history, diabetes, etiology, hypertension, anemia, smoking, stage.
Language: Английский
Citations
1
Clinical Epidemiology and Global Health, Journal Year: 2024, Volume and Issue: 29, P. 101754 - 101754
Published: Aug. 8, 2024
BackgroundHeart failure (HF) is a chronic and progressive condition that significantly impacts patients' lives, necessitating comprehensive understanding of the factors influencing their health outcomes. Among these factors, symptom perception, health-related quality life (HRQoL), predicted survival are paramount. This study aimed to assess HRQoL predictive among HF patients.MethodsA baseline analysis was carried out in randomized controlled trial involving patients with HF. Heart Failure Somatic Perception Scale Kansas City Cardiomyopathy Questionnaire-12 Seattle Model were used.ResultsAmong 160 patients, 62.5 % between 36 59 years age married (88 %). Hypertension diabetes reported 104 94 participants respectively, them, 65 had both hypertension diabetes. The mean left ventricular ejection fraction 33(%), 56.5 New York Association functional class III IV. average perception score 27.4 ± 18.3, while 37.2 14.2. one-year 80 11.5, five-year 38.5 21.3. showed significant negative correlation (r = −0.75; p 0.001) positive 0.53; 0.001), 0.56; 0.001).ConclusionPatients experience persistent symptoms poor HRQoL. Symptom severity decreases Understanding crucial for developing effective self-care interventions, which vital improving patient outcomes managing effectively.
Language: Английский
Citations
0
Frontiers in Cardiovascular Medicine, Journal Year: 2024, Volume and Issue: 11
Published: Aug. 27, 2024
Background Mechanical circulatory support (MCS), temporary or durable, is essential in patients with acute heart failure presenting cardiogenic shock (CS). MCS fundamental advanced when used as a bridge to decision, transplant left ventricular recovery. Limited data on acute-on-chronic (HF) exists the era of axillary mechanical Impella 5.5. We describe case chronic ischemic cardiomyopathy, HF-CS, patient who underwent placement, medical optimization, and explant, now sustained normalization ejection fraction. Case summary A Caucasian female her 50 s was referred our center for evaluation therapies, including transplantation durable assist device placement. Her initial fraction 30% comorbidities multivessel coronary artery disease revascularized 3 vessel bypass grafting ten years prior, type 2 diabetes (A1c 8.6%), peripheral vascular disease. During evaluation, she had decompensation leading required hospitalization inotrope initiation, which unable be weaned. She approved organ listed; however, escalation eventual placement right While support, vasoactive needs reduced, found have recovery tolerated initiation guideline therapy. After three weeks weaned explanted, discharged. remains stable greater than 50% NYHA class 1 functional status at follow-up. One year later, showed myocardial guideline-directed therapy (GDMT). Conclusion Our highlights unique approach long-standing (>5 years) may benefit from early consideration concomitant optimization assess explant native
Language: Английский
Citations
0
The American Journal of Medicine, Journal Year: 2024, Volume and Issue: 137(12), P. e242 - e242
Published: Oct. 16, 2024
Language: Английский
Citations
0