Advances in medical diagnosis, treatment, and care (AMDTC) book series, Journal Year: 2024, Volume and Issue: unknown, P. 115 - 150

Published: Dec. 17, 2024

The utilisation of biomarkers as early warning indicators in assessing illness risk has significantly risen during the past decade. Biomarkers serve indications standard biological processes, disease mechanisms, or pharmacological responses to treatment. and recognition medicine clinical practice influence society. Consequently, its imperative identify specific by noninvasive method. One method involves a proteome glycoproteomic analysis that primarily identifies proteins/glycoproteins tissues serum. Numerous FDA-approved proteins utilised cancer exhibit suboptimal sensitivities for accurate identification. expression phosphoproteins correlates with distinct stage given disease, exhibiting excellent sensitivity specificity. This chapter provides an introduction biomarkers, reviews their sources, explores protein phosphorylation workflow biomarker development, analyses omics technologies discovery, examines future prospects this field.

Language: Английский