Alcohol‐Attributable Cancer: Update From the Global Burden of Disease 2021 Study DOI
Pojsakorn Danpanichkul, Yanfang Pang, Luis Antonio Díaz

et al.

Alimentary Pharmacology & Therapeutics, Journal Year: 2025, Volume and Issue: unknown

Published: April 27, 2025

ABSTRACT Background and Aims Alcohol is a major risk factor for cancer development. Our study aimed to provide the updated global, regional national burden of alcohol‐attributable cancer. Approach Results We analysed Global Burden Disease Study 2021 determine death age‐standardised rate (ASDR) from change these measures between 2000 (reflected as annual percent [APC]), classified by region, nation country's developmental status, which based on sociodemographic index (SDI). In 2021, there were 343,370 deaths globally cancer, was an increase 51%. Alcohol‐attributable accounted 3.5% all deaths. Among liver (27%) highest mortality alcohol, followed oesophageal (24%) colorectal (16%). From ASDR decreased (APC: −0.66%). Regionally, fastest‐growing observed in South Asia. Classified SDI, low 0.33%) low‐to‐middle SDI countries 1.58%) exhibited uptrend While other cancers decreased, early‐onset (15–49 years) lip oral cavity increased 0.40%). Conclusions although declined, total number continued rise. This trend accompanied variations across groups types, particularly gastrointestinal cancers. Urgent efforts are needed both at levels address

Language: Английский

Alcohol‐Attributable Cancer: Update From the Global Burden of Disease 2021 Study DOI
Pojsakorn Danpanichkul, Yanfang Pang, Luis Antonio Díaz

et al.

Alimentary Pharmacology & Therapeutics, Journal Year: 2025, Volume and Issue: unknown

Published: April 27, 2025

ABSTRACT Background and Aims Alcohol is a major risk factor for cancer development. Our study aimed to provide the updated global, regional national burden of alcohol‐attributable cancer. Approach Results We analysed Global Burden Disease Study 2021 determine death age‐standardised rate (ASDR) from change these measures between 2000 (reflected as annual percent [APC]), classified by region, nation country's developmental status, which based on sociodemographic index (SDI). In 2021, there were 343,370 deaths globally cancer, was an increase 51%. Alcohol‐attributable accounted 3.5% all deaths. Among liver (27%) highest mortality alcohol, followed oesophageal (24%) colorectal (16%). From ASDR decreased (APC: −0.66%). Regionally, fastest‐growing observed in South Asia. Classified SDI, low 0.33%) low‐to‐middle SDI countries 1.58%) exhibited uptrend While other cancers decreased, early‐onset (15–49 years) lip oral cavity increased 0.40%). Conclusions although declined, total number continued rise. This trend accompanied variations across groups types, particularly gastrointestinal cancers. Urgent efforts are needed both at levels address

Language: Английский

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