Legume Allergens Pea, Chickpea, Lentil, Lupine and Beyond

Current Allergy and Asthma Reports, Journal Year: 2024, Volume and Issue: 24(9), P. 527 - 548

Published: July 11, 2024

In the last decade, an increasing trend towards a supposedly healthier vegan diet could be observed. However, recently, more cases of allergic reactions to plants and plant-based products such as meat-substitution products, which are often prepared with legumes, were reported. Here, we provide current knowledge on legume allergen sources respective single allergens. We answer question legumes beside well-known food peanut soybean should considered for diagnostic therapeutic measures.

Language: Английский

---

A French consensus proposal: analytical performance targets for total and allergen-specific IgE and total tryptase

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown, P. 100037 - 100037

Published: April 1, 2025

Language: Английский

---

Molecular allergology: a clinical laboratory tool for precision diagnosis, stratification and follow-up of allergic patients

Clinical Chemistry and Laboratory Medicine (CCLM), Journal Year: 2024, Volume and Issue: 62(12), P. 2339 - 2355

Published: May 30, 2024

Abstract Identification of the molecular culprits allergic reactions leveraged allergology applications in clinical laboratory medicine. Molecular shifted focus from complex, heterogeneous allergenic extracts, e.g. pollen, food, or insect venom, towards genetically and immunologically defined proteins available for vitro diagnosis. is a precision medicine approach diagnosis, stratification, therapeutic management, follow-up prognostic evaluation patients within large range diseases. Exclusively nonredundant with any current tools allergy investigation. As an example major application, discrimination genuine sensitization allergen cross-reactivity at level allows proper targeting culprit thus dramatically improves patient management. This review aims introducing specialists to allergology, biochemical genetic bases, through immunological concepts, daily use diagnosis management

Language: Английский

---

Correlated, conflated, and confounded

Annals of Allergy Asthma & Immunology, Journal Year: 2024, Volume and Issue: 132(6), P. 665 - 666

Published: June 1, 2024

Language: Английский

---

Anaphylaxis: Definition and criteria

Journal of Food Allergy, Journal Year: 2024, Volume and Issue: 6(1), P. 26 - 31

Published: July 1, 2024

Anaphylaxis is a systemic allergic reaction that may be severe and life-threatening. With more than dozen anaphylaxis definitions proposed over the past several decades diagnostic criteria in circulation, there need for multinational consensus definition to simplify management across specialties. are alike they different, approaches of National Institute Allergy Infectious Disease, World Organization, Brighton Collaborative help add granularity perspective patient management. occurs spectrum severity within populations, although, among individual patients, some evidence suggest consistency an allergen. Still, influenced by number factors demonstrate variability: relate allergen triggers, characteristics, treatments received. Severity impacts management, recent guidelines provide consider inform both strong conditional recommendations. Conditional recommendations serve as navigational signals shared decision-making when expertise leveraged preferences values together with clinician care bespoke each patient. As novel prevention treatment emerge, understanding significance becomes critical providing individualized appropriate patients at risk anaphylaxis.

Language: Английский

---

Pearls for practice from the 2023 allergy immunology joint task force on practice parameters GRADE and institute of medicine based atopic dermatitis guidelines

Current Opinion in Pediatrics, Journal Year: 2024, Volume and Issue: 36(5), P. 570 - 580

Published: June 18, 2024

Purpose of review To the updated 2023 Allergy Immunology Joint Task Force on Practice Parameters (JTFPP) GRADE and Institute Medicine (IOM) Based Guidelines for management atopic dermatitis. Recent findings Topical corticosteroids and/or calcineurin inhibitors are recommended in individuals with dermatitis refractory to moisturizer alone may be used maintain remission after acute flare control is achieved. Calcineurin a class immunosuppressants effectively manage different autoimmune disorders. Bleach baths allergen immunotherapy beneficial moderate-to-severe disease, while elimination diets, azathioprine, methotrexate, mycophenolate, systemic not recommended. Dupilumab strongly Oral Janus kinase (JAK) carry significant risks; however, this medicines considered cases severe or intolerance dupilumab. Patient preferences regarding cost, availability, feasibility, tolerability should integrated into all treatment plans using shared decision-making approach. Summary The JTFPP Atopic Dermatitis offer up-to-date guidance varying severity infants, children, adults.

Language: Английский

---

Diagnosis and management of shrimp allergy

Frontiers in Allergy, Journal Year: 2024, Volume and Issue: 5

Published: Oct. 18, 2024

Shrimp allergy, the most common food allergy in United States, affects up to 2% of population. Its etiology is multi-factorial with combination genetic predisposition and environmental exposures. This review summarizes latest diagnosis management strategies for shrimp allergy. Currently, double-blind, placebo-controlled challenge gold standard diagnosis. Moreover, mainstream experimental include allergen avoidance, FDA-approved omalizumab, oral immunotherapy. Herein, we emphasize urgent need develop more effective diagnostic tools therapies

Language: Английский

---

Master Clinician: How I Diagnose IgE-Mediated Food Allergy

Annals of Allergy Asthma & Immunology, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Language: Английский

---