Updates and Pearls from the Society of Pediatric Dermatology Meeting DOI

Cathryn Sibbald

Canadian dermatology today., Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 2, 2024

The 49th annual Society of Pediatric Dermatology (SPD) meeting was a tremendous success, attracting over 650 attendees, the highest number ever recorded. 3-day conference featured wide range new developments and tips tricks from experts in field.

Language: Английский

Adverse effects of biologics used to treat asthma DOI Creative Commons
Andrea Sitek, Sergio E. Chiarella, Thanai Pongdee

et al.

Therapeutic Advances in Respiratory Disease, Journal Year: 2025, Volume and Issue: 19

Published: March 1, 2025

In this review, we discuss the risks and adverse effects reported for current Food Drug Association (FDA)-approved biologics used in management of asthma, including omalizumab, benralizumab, dupilumab, mepolizumab, reslizumab, tezepelumab. Our review focuses on risk hypersensitivity reactions, infection, malignancy. Where relevant, have included information regarding cardiovascular disease eosinophilia, specific vaccine use among patients receiving above biologics. We also currently available data context pregnancy. goal is to provide a comprehensive resource providers utilizing these agents, so that they may adequately counsel about therapy identify events if occur.

Language: Английский

Citations

1

Safety and Immunogenicity of Live Attenuated Vaccine Administration in Patients Undergoing Treatment With Dupilumab and Apremilast: A Systematic Review DOI Open Access
Conor Larney, Peter Foley, Benjamin S. Daniel

et al.

Australasian Journal of Dermatology, Journal Year: 2025, Volume and Issue: unknown

Published: March 24, 2025

ABSTRACT Vaccination plays a critical role in protecting against infectious diseases, particularly those with compromised immune systems. While traditional recommendations advise live attenuated vaccination patients undergoing most biologic therapies due to the potential risk of serious infections (vaccine‐related disease caused by unchecked replication vaccine microorganism), emerging evidence and expert opinion suggest vaccines may be safely effectively administered appropriate precautions when using certain medications such as dupilumab apremilast. This systematic review evaluates administration receiving these drugs. A search MEDLINE Embase identified 12 relevant publications, including 2 case series, 3 clinical trials, 7 consensus statements, recommendations, or guidelines. The findings that, circumstances, on precautions. Data apremilast remain limited. Current emphasise shared decision‐making between clinicians patients, considering individual factors. Further is needed establish definitive guidelines therapies.

Language: Английский

Citations

0

Current and Emerging Biologics for Atopic Dermatitis DOI
Michael Z. Nevid, Mark Boguniewicz

Immunology and Allergy Clinics of North America, Journal Year: 2024, Volume and Issue: 44(4), P. 577 - 594

Published: Sept. 2, 2024

Language: Английский

Citations

1

Is it safe and effective to give live viral vaccines to patients on biologics? DOI
Gailen D. Marshall,

James M. Tracy

Annals of Allergy Asthma & Immunology, Journal Year: 2024, Volume and Issue: 133(3), P. 234 - 235

Published: July 3, 2024

Language: Английский

Citations

1

O uso do Dupilumabe no tratamento da esofagite eosinofílica DOI Creative Commons

Myckanne Medeiros,

Eli Pinto Barbalho Filho,

Ingrid Holanda Guedes

et al.

Brazilian Journal of Implantology and Health Sciences, Journal Year: 2024, Volume and Issue: 6(8), P. 535 - 545

Published: Aug. 4, 2024

Introdução: A esofagite eosinofílica tem crescido nos últimos anos. Seus sintomas são incapacitantes e trazem prejuízos na qualidade de vida seus portadores. O tratamento convencional falha em muitos casos. imunobiológico dupilumabe se apresenta como alternativa no dessa doença, por meio do bloqueio da atividade Interleucina IL-4 IL-13. Metodologia: Realizou-se uma pesquisa bibliográfica nas plataformas Scielo, Biblioteca Virtual Saúde PubMed. No total, foram identificadas 1268 publicações, com os descritores “esofagite eosinofílica” “dupilumabe”. Após avaliação metodológica, 22 publicações entre 2019 2024 português, espanhol inglês incluídas. Resultados Discussão: foi capaz reduzir as contagens eosinófilos esofágicos melhorar significativamente a histologia esôfago todas apresentações doença. tipo fibroestenótico, medicação conseguiu remissão 100% dos casos estudados. Ademais, apresentou resultados excelentes quando utilizado portadores outras patologias atópicas concomitantes. Em alguns estudos, visualizada capacidade melhoria funcionalidade esôfago. alívio registrado maioria mas não houve unanimidade. Conclusão: representa um importante aliado refratária à medicações primeira linha. Entranto, seu alto custo recente incorporação ao acervo terapêutico doença constituem desafios serem superados. É necessário realização novos principalmente longo prazo, sobre eficácia droga, dose duração necessárias.

Citations

0

ABCs of Biologics in Pediatric Eczema: An Updated Review on the Safety and Efficacy of Systemic Treatments for Pediatric Atopic Dermatitis and Future Directions DOI

Sarah Kamsiah Zemlok,

JiaDe Yu

Current Dermatology Reports, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 25, 2024

Language: Английский

Citations

0

Updates and Pearls from the Society of Pediatric Dermatology Meeting DOI

Cathryn Sibbald

Canadian dermatology today., Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 2, 2024

The 49th annual Society of Pediatric Dermatology (SPD) meeting was a tremendous success, attracting over 650 attendees, the highest number ever recorded. 3-day conference featured wide range new developments and tips tricks from experts in field.

Language: Английский

Citations

0