Animals,
Journal Year:
2024,
Volume and Issue:
15(1), P. 9 - 9
Published: Dec. 24, 2024
The
aim
of
this
study
was
to
investigate
the
effects
terpinen-4-ol
(TER)
supplementation
on
intestinal
barrier
function
pigs.
Five
groups
fifty
28-day-old
piglets
with
comparable
body
weights
were
randomly
assigned
following
groups:
control
group
(CON),
lipopolysaccharide
(LPS),
low
TER
(PLT),
middle
(PMT),
and
high
(PHT).
basal
diet
given
CON
LPS
groups,
30,
60,
or
90
mg/kg
added
for
groups.
After
21-day
trial
period,
in
received
an
intraperitoneal
injection
100
μg/kg
weight
LPS,
whereas
0.9%
normal
saline
solution.
results
showed
that
stimulation
resulted
a
decrease
(p
<
0.05)
depth
colonic
crypts
piglets,
which
greater
group.
Compared
those
group,
number
goblet
cells
MUC2
expression
decreased
colon
while
these
parameters
increased
PMT
0.05).
malondialdehyde
(MDA)
content
than
activities
glutathione
peroxidase
(GSH-Px),
superoxide
dismutase
(SOD),
catalase
(CAT)
lower
group;
conversely,
MDA
colons
PLT
also
reduced
LPS-induced
upregulation
IL-1β
TNF-α
expression,
along
relative
gene
NLRP3,
ASC,
caspase-1
abundances
Firmicutes
UCG-005
0.05),
significantly
abundance
Proteobacteria
Actinobacteria
Phascolarctobacterium
PHT
compared
In
conclusion,
effectively
improved
weaning
piglets.
Based
study,
appropriate
dose
diets
60
mg/kg.
Frontiers in Microbiology,
Journal Year:
2024,
Volume and Issue:
15
Published: Oct. 28, 2024
Glucose
oxidase
(GOD)
has
been
investigated
as
a
potential
additive
for
enhancing
intestinal
health
and
growth
performance
in
poultry.
However,
limited
research
exists
on
the
effects
of
ultra-high
doses
GOD
practical
poultry
production.
This
study
aimed
to
investigate
impact
high
dietary
levels
broiler
performance,
antioxidant
capacity,
microbiota.
A
total
400
healthy,
1-day-old,
slow-growing
chickens
were
randomly
assigned
four
treatment
groups.
The
control
group
was
fed
standard
basal
diet,
while
other
groups
(G1,
G2,
G3)
diet
supplemented
with
4
U/g,
20
100
U/g
VTR
GOD,
respectively.
results
showed
that
dose
significantly
improved
final
body
weight
average
daily
feed
intake
(ADFI)
(
p
<
0.05).
Additionally,
G3
exhibited
marked
increase
glutathione
peroxidase
(GSH-Px)
activity
0.05),
reflecting
enhanced
function.
Gut
morphology
remained
intact
across
all
groups,
indicating
no
adverse
barrier
integrity.
Microbiota
analysis
revealed
significant
increases
0.05)
Firmicutes
Verrucomicrobiota
abundance
at
phylum
level
GOD-supplemented
Moreover,
treatments
increased
Faecalibacterium
,
Mucispirllum
CHKCI001
genus
level.
Metabolic
function
predictions
suggested
high-dose
supplementation
enriched
carbohydrate
metabolism,
particularly
starch
sucrose
metabolism.
Correlation
indicated
CHCKI001
two
bacteria
strongly
influenced
by
associated
gut
health.
In
conclusion,
had
demonstrated
benefits,
promoting
both
broilers.
Frontiers in Immunology,
Journal Year:
2024,
Volume and Issue:
15
Published: Nov. 4, 2024
Various
problems
and
obstacles
are
encountered
during
pig
farming,
especially
the
weaning
phase
when
switching
from
liquid
to
solid
feed.
Infection
by
pathogenic
bacteria
causes
damage
intestinal
barrier
function
of
piglets,
disrupts
balance
microbiota,
destroys
chemical,
mechanical,
immune
barriers
tract,
which
is
one
main
gut
inflammation
or
diseases
in
piglets.
The
traditional
method
add
antibiotics
piglet
diets
prevent
bacterial
infections.
However,
long-term
overuse
leads
resistance
residues
animal
products,
threatening
human
health
causing
microbiota
dysbiosis.
In
this
context,
finding
alternatives
maintain
pre-
post-weaning
piglets
infections
becomes
a
real
emergency.
utilization
probiotics
nutrition
has
emerged
as
pivotal
strategy
promote
defend
against
infections,
offering
sustainable
alternative
antibiotic
usage.
This
review
introduces
recent
findings
that
underscore
multifaceted
roles
enhancing
welfare,
fortifying
mitigating
impacts
common
pathogens.
Meanwhile,
study
functions
different
perspectives:
positive
effects
on
health,
protecting
pathogen
infection,
mechanisms
preventing
bacteria.
Animals,
Journal Year:
2024,
Volume and Issue:
14(23), P. 3511 - 3511
Published: Dec. 4, 2024
This
study
investigated
the
efficacy
of
using
probiotics
on
performance
and
health
parameters
sows
their
litters.
A
randomized
block
design
was
used
with
584
292
replications,
two
dietary
treatments:
control
group
(basal
diet
without
probiotics)
probiotic
supplemented
400
g/ton
a
composed
Animals,
Journal Year:
2024,
Volume and Issue:
15(1), P. 9 - 9
Published: Dec. 24, 2024
The
aim
of
this
study
was
to
investigate
the
effects
terpinen-4-ol
(TER)
supplementation
on
intestinal
barrier
function
pigs.
Five
groups
fifty
28-day-old
piglets
with
comparable
body
weights
were
randomly
assigned
following
groups:
control
group
(CON),
lipopolysaccharide
(LPS),
low
TER
(PLT),
middle
(PMT),
and
high
(PHT).
basal
diet
given
CON
LPS
groups,
30,
60,
or
90
mg/kg
added
for
groups.
After
21-day
trial
period,
in
received
an
intraperitoneal
injection
100
μg/kg
weight
LPS,
whereas
0.9%
normal
saline
solution.
results
showed
that
stimulation
resulted
a
decrease
(p
<
0.05)
depth
colonic
crypts
piglets,
which
greater
group.
Compared
those
group,
number
goblet
cells
MUC2
expression
decreased
colon
while
these
parameters
increased
PMT
0.05).
malondialdehyde
(MDA)
content
than
activities
glutathione
peroxidase
(GSH-Px),
superoxide
dismutase
(SOD),
catalase
(CAT)
lower
group;
conversely,
MDA
colons
PLT
also
reduced
LPS-induced
upregulation
IL-1β
TNF-α
expression,
along
relative
gene
NLRP3,
ASC,
caspase-1
abundances
Firmicutes
UCG-005
0.05),
significantly
abundance
Proteobacteria
Actinobacteria
Phascolarctobacterium
PHT
compared
In
conclusion,
effectively
improved
weaning
piglets.
Based
study,
appropriate
dose
diets
60
mg/kg.
