Butyrate Supplementation Improves Intestinal Health and Growth Performance in Livestock: A Review
Biomolecules,
Journal Year:
2025,
Volume and Issue:
15(1), P. 85 - 85
Published: Jan. 8, 2025
Butyrate
supplementation
has
gained
considerable
attention
for
its
potential
benefits
in
livestock,
particularly
concerning
intestinal
health
and
growth
performance.
This
review
synthesizes
recent
research
on
the
diverse
roles
of
butyrate,
across
various
livestock
species.
As
a
short-chain
fatty
acid,
butyrate
is
known
enhancing
development,
improving
immune
function,
modulating
microbial
diversity.
Studies
indicate
that
supports
gut
barrier
integrity,
reduces
inflammation,
optimizes
feed
efficiency,
especially
during
critical
weaning
post-weaning
periods
calves,
piglets,
lambs.
Supplementation
with
been
shown
to
increase
average
daily
gain
(ADG),
improve
microbiota
balance,
promote
growth,
enhance
health,
boost
antioxidant
capacity,
reduce
diarrhea.
Additionally,
plays
role
epigenetic
regulation
gene
expression
through
histone
acetylation,
influencing
tissue
development
modulation.
Its
anti-inflammatory
effects
have
demonstrated
species,
positioning
as
therapeutic
agent
animal
nutrition.
suggests
optimizing
strategies
meet
specific
needs
each
species
may
yield
additional
benefits,
establishing
an
important
dietary
additive
performance
livestock.
Language: Английский
Sheep-Derived Lactobacillus johnsonii M5 Enhances Immunity and Antioxidant Capacity, Alleviates Diarrhea, and Improves Intestinal Health in Early-Weaned Lambs
Microorganisms,
Journal Year:
2025,
Volume and Issue:
13(2), P. 404 - 404
Published: Feb. 13, 2025
The
early
weaning
of
lambs
frequently
leads
to
weakened
immunity,
impaired
intestinal
function,
and
increased
susceptibility
disease.
Lactobacillus
plays
a
role
in
regulating
enhancing
antioxidant
capacity,
maintaining
health.
This
study
aims
isolate
strain
with
favorable
probiotic
properties
from
sheep
feces
investigate
its
effects
on
the
health
early-weaned
lambs.
In
this
study,
growth
characteristics,
acid
production
bacteriostatic
bile
salt
tolerance,
gastrointestinal
fluid
self-coagulation
surface
hydrophobicity
isolated
were
analyzed
for
vitro
properties.
Lactobacilli
strong
used
vivo
validation.
A
total
72
Hu
allocated
into
four
groups:
ewe-reared
group
(ER),
early-weaning
(EW),
low-dose
(LL),
high-dose
(HL).
Early
was
performed
EW,
LL,
HL
groups
at
age
28
days.
johnsonii
M5
(L.
M5),
feces,
exhibited
vitro.
Feeding
EW
low
dose
L.
significantly
reduced
their
diarrhea
rate
(p
<
0.05).
Its
supplementation
levels
superoxide
dismutase
(SOD),
catalase
(CAT),
glutathione
peroxidase
(GSH-Px)
capacity
(T-AOC)
serum
jejunal
mucosa
decreased
malondialdehyde
(MDA)
Compared
group,
immunoglobulin
G
(IgG)
LL
feeding
content
anti-inflammatory
cytokines,
while
reducing
pro-inflammatory
cytokines
also
crypt
depth
occludin
claudin-1
These
findings
indicate
that
enhances
immunity
improving
health,
mitigates
Language: Английский