Animal Reproduction Science, Journal Year: 2024, Volume and Issue: 267, P. 107520 - 107520
Published: May 31, 2024
Language: Английский
Animal Reproduction Science, Journal Year: 2024, Volume and Issue: 267, P. 107520 - 107520
Published: May 31, 2024
Language: Английский
Animal Reproduction Science, Journal Year: 2024, Volume and Issue: 263, P. 107456 - 107456
Published: March 16, 2024
Language: Английский
Citations
8Journal of Developmental Origins of Health and Disease, Journal Year: 2025, Volume and Issue: 16
Published: Jan. 1, 2025
Abstract Adverse environmental conditions during early life are known to determine adult metabolic phenotype in laboratory species and human populations. However, less is about developmental programming of livestock, given their size longevity compared animals. As maternal and/or fetal glucocorticoid (GC) concentrations rise stressful pregnancy, GCs may act as a common mechanism linking early-life the subsequent phenotype. This review examines prenatal longer-term postnatal metabolism by GC overexposure livestock with particular emphasis on sheep. It effects both cortisol, natural more potent synthetic used clinically treat threatened pre-term delivery other pregnancy. considers early- specific feto-placental tissues relation changes growth trajectory, hormones functioning hypothalamic–pituitary–adrenal axis itself. highlights role maturational signals development fit for survival at birth future homeostatic challenges. ensuing induced become inappropriate prevailing lead dysfunction functional reserves decline age. Further studies needed establish whether outcomes sex-linked, pronounced old age inherited transgenerationally these species.
Language: Английский
Citations
0Theriogenology, Journal Year: 2024, Volume and Issue: 228, P. 17 - 29
Published: July 24, 2024
Language: Английский
Citations
1Animal Reproduction Science, Journal Year: 2024, Volume and Issue: 267, P. 107520 - 107520
Published: May 31, 2024
Language: Английский
Citations
0