Journal of Evaluation in Clinical Practice,
Journal Year:
2023,
Volume and Issue:
29(6), P. 1039 - 1053
Published: June 14, 2023
Abstract
Rationale
Older
adults
are
at
high
risk
of
developing
delirium
in
the
emergency
department
(ED);
however,
it
is
often
missed
or
undertreated.
Improving
ED
care
challenging
part
due
to
a
lack
standards
guide
best
practice.
Clinical
practice
guidelines
(CPGs)
translate
evidence
into
recommendations
improve
Aim
To
critically
appraise
and
synthesize
CPG
for
relevant
older
patients.
Methods
We
conducted
an
umbrella
review
retrieve
CPGs.
Quality
CPGs
their
were
appraised
using
Appraisal
Guidelines,
Research,
Evaluation
(AGREE)‐II;
Guidelines
Research
Evaluation—Recommendations
Excellence
(AGREE‐REX)
instruments.
A
threshold
70%
greater
AGREE‐II
Rigour
Development
domain
was
used
define
high‐quality
Delirium
from
meeting
this
included
synthesis
narrative
analysis.
Results
scores
ranged
37%
83%,
with
5
10
predefined
threshold.
AGREE‐REX
overall
calculated
44%
80%.
Recommendations
grouped
screening,
diagnosis,
reduction,
management.
Although
none
ED‐specific,
many
incorporated
setting.
There
agreement
that
screening
nonmodifiable
factors
important
high‐risk
populations,
those
should
be
screened
delirium.
The
‘4A's
Test’
recommended
tool
use
specifically.
Multicomponent
strategies
its
management
if
occurs.
only
area
disagreement
short‐term
antipsychotic
medication
urgent
situations.
Conclusion
This
first
known
including
critical
appraisal
recommendations.
Researchers
policymakers
can
inform
future
improvement
efforts
research
ED.
Registration
study
has
been
registered
Open
Science
Framework
registries:
https://doi.org/10.17605/OSF.IO/TG7S6OSF.IO/TG7S6
.
British Journal of Clinical Pharmacology,
Journal Year:
2023,
Volume and Issue:
89(8), P. 2508 - 2518
Published: March 29, 2023
Comprehensively
investigate
prescribing
in
usual
care
of
hospitalized
older
people
with
respect
to
polypharmacy;
potentially
inappropriate
medications
(PIMs)
according
Beers
criteria;
and
cumulative
anticholinergic
sedative
medication
exposure
calculated
Drug
Burden
Index
(DBI).
Specifically,
quantify
these
measures
on
admission,
changes
between
admission
discharge,
associations
adverse
outcomes
costs.Established
new
retrospective
inpatient
cohort
2000
adults
aged
≥75
years,
consecutively
admitted
6
hospitals
Sydney,
Australia,
detailed
information
medications,
clinical
characteristics
outcomes.
Conducted
cross-sectional
analyses
index
data
from
cohort.Cohort
had
mean
(standard
deviation)
age
86.0
(5.8)
59%
female,
21%
residential
care.
On
prevalence
polypharmacy
was
77%,
PIMs
34%
DBI
>
0
53%.
From
difference
(95%
confidence
interval)
total
number
increased
1.05
(0.92,
1.18);
while
(-3.8%
[-5.4,
-2.1])
score
(-0.02
[-0.04,
-0.01])
decreased.
were
associated
risks
(adjusted
odds
ratio
[95%
interval])
falls
(PIMs
1.63
[1.28,
2.08];
1.21[1.00,
1.46])
delirium
1.76
[1.38,
1.46];
1.42
[1.19,
1.71]).
Each
measure
risk
drug
reactions
(polypharmacy
1.71];
1.87
[1.40,
2.49];
1.90
[1.55,
2.15]).
Cost
(AU$/patient/hospital
day)
contributing
low
($0.29
$0.88).In
this
large
inpatients,
hospital
results
an
increase
small
reductions
DBI,
variable
BMJ Open,
Journal Year:
2023,
Volume and Issue:
13(7), P. e072908 - e072908
Published: July 1, 2023
Emergency
department
(ED)
care
must
adapt
to
meet
current
and
future
demands.
In
Australia,
ED
quality
measures
(eg,
prolonged
length
of
stay,
re-presentations
or
patient
experience)
are
worse
for
older
adults
with
multiple
comorbidities,
people
who
have
a
disability,
those
present
mental
health
condition,
Indigenous
Australians,
culturally
linguistically
diverse
(CALD)
background.
Strengthened
performance
relies
on
understanding
the
social
systemic
barriers
preferences
these
different
cohorts,
identifying
viable
solutions
that
may
result
in
sustained
improvement
by
service
providers.
A
collaborative
5-year
project
(MyED)
aims
codesign,
users
providers,
new
adapted
models
improve
performance,
outcomes
experience
five
cohorts.
Experience-based
codesign
using
mixed
methods,
set
three
hospitals
one
district
Australia.
This
protocol
introduces
staged
incremental
approach
whole
project,
details
first
research
elements:
ethnographic
observations
at
interface,
interviews
providers
two
cohorts-older
CALD
We
aim
sample
range
participants,
carefully
tailoring
recruitment
support.
Ethics
approval
has
been
obtained
from
Western
Sydney
Local
Health
District
Human
Research
Committee
(2022/PID02749-2022/ETH02447).
Prior
informed
written
consent
will
be
all
participants.
Findings
each
stage
submitted
peer-reviewed
publication.
Project
outputs
disseminated
implementation
more
widely
across
New
South
Wales,
Healthcare,
Journal Year:
2023,
Volume and Issue:
11(4), P. 593 - 593
Published: Feb. 16, 2023
Background:
Due
to
the
increase
in
life
expectancy,
both
general
population
and
of
patients
emergency
departments
(ED)
are
getting
older.
An
understanding
differences,
workload
resource
requirements
may
be
helpful
improving
patient
care.
The
main
goal
this
study
was
evaluate
reasons
for
geriatric
admissions
ED,
identify
typical
medical
problems
assess
number
resources
order
provide
more
effective
management.
Methods:
We
examined
35,720
elderly
patients'
ED
visits
over
course
3
years.
data
collected
included
age,
sex,
timing
length
stay
(LOS),
use
various
resources,
endpoint
(admission,
discharge
or
death)
ICD-10
diagnoses.
Results:
median
age
73
years
[66-81],
with
females
(54.86%).
There
were
57.66%
(G1),
36.44%
senile
(G2)
5.89%
long-liver
(G3)
patients.
older
groups.
total
admission
rate
37.89%
(34.19%
G1,
42.21%
G2
47.33%
G3).
average
patient's
150
min
[81-245]
(G3
180
[108-277],
(162
[92-261])
G1
139
[71-230]).
Heart
failure,
atrial
fibrillation
hip
fracture
most
common
Nonspecific
diagnoses
all
Conclusion:
vast
majority
required
considerable
resources.
With
increasing
ages,
women,
LOS
increased.
Journal of Evaluation in Clinical Practice,
Journal Year:
2023,
Volume and Issue:
29(6), P. 1039 - 1053
Published: June 14, 2023
Abstract
Rationale
Older
adults
are
at
high
risk
of
developing
delirium
in
the
emergency
department
(ED);
however,
it
is
often
missed
or
undertreated.
Improving
ED
care
challenging
part
due
to
a
lack
standards
guide
best
practice.
Clinical
practice
guidelines
(CPGs)
translate
evidence
into
recommendations
improve
Aim
To
critically
appraise
and
synthesize
CPG
for
relevant
older
patients.
Methods
We
conducted
an
umbrella
review
retrieve
CPGs.
Quality
CPGs
their
were
appraised
using
Appraisal
Guidelines,
Research,
Evaluation
(AGREE)‐II;
Guidelines
Research
Evaluation—Recommendations
Excellence
(AGREE‐REX)
instruments.
A
threshold
70%
greater
AGREE‐II
Rigour
Development
domain
was
used
define
high‐quality
Delirium
from
meeting
this
included
synthesis
narrative
analysis.
Results
scores
ranged
37%
83%,
with
5
10
predefined
threshold.
AGREE‐REX
overall
calculated
44%
80%.
Recommendations
grouped
screening,
diagnosis,
reduction,
management.
Although
none
ED‐specific,
many
incorporated
setting.
There
agreement
that
screening
nonmodifiable
factors
important
high‐risk
populations,
those
should
be
screened
delirium.
The
‘4A's
Test’
recommended
tool
use
specifically.
Multicomponent
strategies
its
management
if
occurs.
only
area
disagreement
short‐term
antipsychotic
medication
urgent
situations.
Conclusion
This
first
known
including
critical
appraisal
recommendations.
Researchers
policymakers
can
inform
future
improvement
efforts
research
ED.
Registration
study
has
been
registered
Open
Science
Framework
registries:
https://doi.org/10.17605/OSF.IO/TG7S6OSF.IO/TG7S6
.