Dual acid-base catalysis with biologically modified graphene oxide: a sustainable route to polyhydroquinolines with antimicrobial properties

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: March 25, 2025

This article conducts an in-depth examination of graphene oxide-aspartic acid (GO-As) as a novel bifunctional nano-organocatalyst distinguished by both catalytic and antibacterial properties. The research elucidates the synthesis GO through Hummer's method, followed covalent attachment aspartic to surface nanosheets. innovative approach is particularly notable it circumvents use hazardous chemicals, thereby promoting environmental sustainability. newly developed catalyst underwent rigorous analysis employing variety spectroscopic techniques, including Fourier Transform Infrared (FT-IR) spectroscopy, Energy-Dispersive X-ray Spectroscopy (EDX), mapping, Field Emission Scanning Electron Microscopy (SEM), diffraction (XRD), thermogravimetric (TGA), Raman spectroscopy. findings indicate that effectively synthesizes polyhydroquinoline derivatives while demonstrating significant stability over multiple reuse cycles, underscoring its potential applicability in organic synthesis. Furthermore, properties GO-modified were evaluated against six pathogenic bacterial species. results reveal substantial activity Gram-positive Gram-negative strains, two antibiotic-resistant bacteria: Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant Enterococcus (VRE), Raman. In conclusion, investigation GO-As heterogeneous represents promising advancement development environmentally friendly effective catalysts with noteworthy characteristics.

Language: Английский

Exploring green catalysis with Zn(II)-chitosan-alginate beads for pyran and pyranopyrazole synthesis

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 144131 - 144131

Published: May 1, 2025

Language: Английский