Practical Recommendations for Exercise Training in Patients with Long COVID with or without Post-exertional Malaise: A Best Practice Proposal

Sports Medicine - Open, Journal Year: 2024, Volume and Issue: 10(1)

Published: April 24, 2024

Abstract People with long COVID may suffer from a wide range of ongoing symptoms including fatigue, exertional dyspnea, reduced exercise performance, and others. In particular, impaired performance is condition that can be recovered in many people through an individualized physical training program. However, clinical experience has shown the presence post-exertional malaise (PEM) significant barrier to COVID. Currently, there no guideline or consensus available on how apply this cohort. Therefore, we conducted literature review PubMed library using following search terms: “COVID”, “post-COVID”, “long COVID” “exercise” searching for studies January 2020 2024. Data 46 trials were included. Exercise regimes very heterogeneous none these reported management PEM context Based feedback additional survey was answered by 14 international experts field COVID, combined authors´ own extensive practical experience, best practice proposal recommendations been developed. This differentiates procedures according no, mild/moderate severe These guide allied healthcare professionals worldwide initiating adjusting programs stratified severity PEM.

Language: Английский

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The Management of Postpartum Cardiorespiratory Failure in a Patient with COVID-19 and Sickle Cell Trait Requiring Extraorporeal Membrane Oxygenation Support and Airflight Transportation

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(1), P. 213 - 213

Published: Jan. 2, 2025

Acute cardiovascular disorders are incriminated in up to 33% of maternal deaths, and the presence sickle cell anemia (SCA) aggravates risk peripartum complications. Herein, we present a 24-year-old Caribbean woman with known SCA who developed vaso-occlusive crisis at 36 weeks gestation that required emergency Cesarean section. In early postpartum period, she experienced fever rapid onset acute respiratory distress context COVID-19 infection tracheal intubation mechanical ventilatory support broad-spectrum antibiotics blood exchange transfusion. Shortly thereafter, transthoracic echocardiography documented severe biventricular dysfunction associated raising levels cardiac troponin ECG signs myocardial ischemia. Medical treatment incremental dobutamine noradrenaline infusion failed improve output gas exchange. After consultation regional center, prompt decision was made provide via implantation femoral cannula initiation veno-arterial extracorporeal membrane oxygenation (ECMO, Cardiohelp®). Under stable ECMO, patient transferred by helicopter specialized center. There were no ongoing hemolysis, progressive recovery right left ventricular function facilitated forward flow through aortic valve. Three days after implantation, ECMO weaned, removed. One day later, patient’s chest X-rays showed partial resolution lung edema. The successfully extubated, non-invasive ventilation pulmonary rehabilitation initiated speed her functional recovery.

Language: Английский

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Telerehabilitation in patients with long COVID-19 syndrome

European Journal of Internal Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

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Effect of pulmonary rehabilitation for patients with long COVID-19: a systematic review and meta-analysis of randomized controlled trials

Therapeutic Advances in Respiratory Disease, Journal Year: 2025, Volume and Issue: 19

Published: Jan. 1, 2025

Background: Pulmonary rehabilitation (PR) has demonstrated efficacy in managing long COVID-19, underscoring the need to refine and tailor PR strategies for optimal patient outcomes. Objectives: To evaluate impact of on patients with COVID-19 compare different types durations interventions. Design: Systematic review meta-analysis. Data sources methods: We systematically searched randomized controlled trials (RCTs) effectiveness published before April 2024. The primary outcomes were physical capacity assessed by 6-minute walking test (6MWT), lung function measured forced expiratory volume first second (FEV1) vital (FVC), health-related quality life (HRQoL), fatigue. Secondary thirty-second sit-to-stand (30STST), handgrip strength tests, maximal inspiratory pressure (MIP), (MEP), dyspnea, depression, anxiety, perceived effort, adverse events. Results: A total 37 studies 3363 included. Compared controls, improved (6MWT, 30STST, handgrip), (FEV1, FVC, MIP, MEP), HRQoL, fatigue, anxiety but did not reach statistical significance depression. Subgroup analyses duration indicated that programs ⩽4 weeks 6MWT; those between 4 8 significantly 6MWT, FVC), reduced fatigue; over HRQoL Exercise type analysis revealed breathing exercises HRQoL; multicomponent enhanced 6MWT performance combination both FEV1 (L), FVC (%pred), Conclusion: improves capacity, function, alleviates patients. 4- 8-week program a breath training is most effective long-term syndromes. Trial registration: PROSPERO ID: CRD42024455008.

Language: Английский

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Effect of a 4-week pulmonary telerehabilitation program for people with respiratory post-acute sequelae of COVID-19 – A randomised controlled trial

European Journal of Physiotherapy, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 10

Published: March 19, 2025

Language: Английский

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Multimodal Telerehabilitation in Post COVID-19 Condition Recovery: A Series of 12 Cases

Reports — Medical Cases Images and Videos, Journal Year: 2025, Volume and Issue: 8(1), P. 35 - 35

Published: March 20, 2025

Background: Post COVID-19 Condition is a recently recognized syndrome characterized by the persistence of various symptoms, including dyspnea, physical and mental fatigue, post-exertional malaise. Currently, there no established treatment or clear consensus on effectiveness rehabilitation, given that patients could benefit from home-based telerehabilitation, defined as remote rehabilitation using telematic systems, may be an option to reach more population with persistent symptoms. Therefore, it necessary show efficacy this approach benefits multimodal strategy in these patients. Methods: Patients underwent home 12-week synchronous telerehabilitation system. The intervention included therapeutic education respiratory rehabilitation. following variables were analyzed: Fatigue, quality life, strength, aerobic capacity, upper lower limb strength. Conclusions: After 12 weeks, significant improvements found However, improvement was dyspnea scores, which did not correlate Interestingly, post-intervention correlation emerged between distance covered capacity perceived suggesting asynchronous viable for

Language: Английский

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Responders to a rehabilitation program for adults with post-COVID-19 condition: An observational study

Annals of Physical and Rehabilitation Medicine, Journal Year: 2025, Volume and Issue: 68(4), P. 101980 - 101980

Published: April 17, 2025

Language: Английский

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ARACOV-02. Specialized nutritional intervention and telerehabilitation in patients with long COVID: Protocol of a randomized controlled trial

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(4), P. e0321811 - e0321811

Published: April 29, 2025

Background It is estimated that at least 10% of the population infected with SARS-CoV-2 develop Post COVID Condition, which characterized by a diverse array symptoms including dyspnea, fatigue, anxiety, depression, and deterioration in quality life. The virus can trigger an excessive immune response, release pro-inflammatory cytokines IL-6, IL-1, TNFα reactive oxygen species. Specialized Pro Resolving Mediators (SPMs) (17-HAD, 14-HAD 18_HEPE) could be useful Condition modulating inflammatory response. objective to determine change life, profile, functional capacity emotional variables group taking nutritional supplement plus telerehabilitation programme. Methods ARACOV-2 study double-blind, parallel-group, randomized control trial two parallel interventions: Nutritional vs placebo telerehabilitation. primary endpoint will life (EQ-5L-5D). intervention last 12 weeks daily intake omega-3 or supervised rehabilitation programme using Discussion This suggests SPMs supplementation combined may improve inflammation like fatigue patients. Both interventions have anti-inflammatory potential, their use enhance physical mental health outcomes. approach offers promising strategy for managing symptoms. Trial registration ClinicalTrials.gov NCT06063031

Language: Английский

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Effectiveness of telerehabilitation in patients with post-COVID-19: a systematic review and meta-analysis of randomised controlled trials

BMJ Open, Journal Year: 2024, Volume and Issue: 14(7), P. e074325 - e074325

Published: July 1, 2024

Objective To assess the effects of telerehabilitation on clinical symptoms, physical function, psychological function and quality life (QoL) in patients with post-COVID-19. Design Systematic review meta-analysis randomised controlled trials (RCTs). Data sources PubMed, Web Science, Embase Cochrane Library were searched for publications from 1 January 2020 to 17 April 2024. Eligibility criteria RCTs investigating post-COVID-19 included. The outcomes interest encompassed QoL. Only studies reported English extraction synthesis Two reviewers independently extracted data evaluated risk bias. Statistical analysis was conducted using Review Manager V.5.3, employing mean difference (MD) a 95% CI, corresponding P value used ascertain treatment effect between groups. Heterogeneity quantified I 2 statistic. evidence assessed by GRADE. Results 16 (n=1129) included this systematic review, 15 which (n=1095, comparisons) meta-analysis. primary pooled demonstrated that, compared no rehabilitation or usual care, can improve (measured 30 s sit-to-stand test [6 RCTs, n=310, MD=1.58 stands, CI 0.50 2.66; p=0.004]; 6 min walking distance n=324, MD=76.90 m, 49.47 104.33; p<0.00001]; 36-item short-form health survey [5 n=380, MD=6.12 units, 2.85 9.38; p=0.0002]). However, results did not indicate significant improvements pulmonary graded as low Hospital Anxiety Depression Scale-anxiety very other outcomes. overall completion rate 78.26%, reports severe adverse events any trials. Conclusions Despite lack certain variables, could be an effective safe option enhancing It is advisable conduct further well-designed continue in-depth exploration topic. Study registration PROSPERO, CRD42023404647.

Language: Английский

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Implementing a Pulmonary Telerehabilitation Program for Young Adults with Post-COVID-19 Conditions: A Pilot Study

Healthcare, Journal Year: 2024, Volume and Issue: 12(18), P. 1864 - 1864

Published: Sept. 16, 2024

Background: Several studies have shown that pulmonary telerehabilitation (PTR) improves respiratory capacity. However, there is little evidence of its effectiveness in youth with post-COVID-19 conditions (PCC). This study analyzed the effects a PTR program on young adults PCC. Methods: Sixteen youths were randomly assigned to control group (CG) or an experimental (EG), eight participants each. The EG participated included twelve remote, asynchronous four-week sessions diaphragmatic breathing and aerobic exercises. Vital signs (SpO2, HR, RR, BP), physical capacity (sit-to-stand test), cardiorespiratory (6-Minute Walk Test), perceived exertion (Borg scale) assessed both groups. Results: Statistical analyses showed significant decrease RR HR (p < 0.012) increase SpO2 0.042), 0.012), 0.028) Perceived effort decreased significantly groups (CG: p 0.006; EG: 0.001) only for but not 0.106). There no statistical changes registered BP > 0.05). Conclusions: program, which includes exercises, feasible effective improving people PCC, as well reducing dyspnea.

Language: Английский

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