Authorea (Authorea),
Journal Year:
2023,
Volume and Issue:
unknown
Published: May 17, 2023
Taste
is
one
of
the
basic
senses
living
organisms
and
can
recognize
sour,
bitter,
salty,
sweet
umami
tastes.
Bitter
taste
receptor
a
class
G
protein-coupled
receptors
capable
sensing
bitterness.
Initially,
bitter
was
thought
to
be
only
found
in
buds
tongue,
palate
throat.
Recent
research
has
shown
that
addition
oral
cavity,
also
present
intestinal
tract,
respiratory
urinary
vascular
smooth
muscle,
nervous
system,
thyroid
gland
other
tissues
organs
regulate
body
homeostasis
resist
disorders
.
In
this
review,
we
focus
on
effects
outside
cavity
lay
groundwork
for
future
research.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(4), P. 2251 - 2251
Published: Feb. 13, 2024
This
review
focuses
on
the
question
of
metabolic
syndrome
(MS)
being
a
complex,
but
essentially
monophyletic,
galaxy
associated
diseases/disorders,
or
just
related
rather
independent
pathologies.
The
human
nature
MS
(its
exceptionality
in
Nature
and
its
close
interdependence
with
action
evolution)
is
presented
discussed.
text
also
describes
components,
special
emphasis
description
their
interrelations
(including
syndromic
development
recruitment),
as
well
consequences
upon
energy
handling
partition.
main
theories
MS’s
origin
are
relation
to
hepatic
steatosis,
type
2
diabetes,
obesity,
encompass
most
components
described
so
far.
differential
effects
sex
biological
considered
under
light
social
needs
evolution,
which
directly
epidemiology,
severity,
relations
senescence.
triggering
maintenance
factors
discussed,
especial
inflammation,
complex
process
affecting
different
levels
organization
critical
element
for
development.
Inflammation
operation
connective
tissue
adipose
organ)
widely
studied
acknowledged
influence
diet.
role
diet
composition,
including
transcendence
anaplerotic
Krebs
cycle
from
dietary
amino
acid
supply
(and
timing),
developed
context
testosterone
β-estradiol
control
insulin-glycaemia
core
system
carbohydrate-triacylglycerol
handling.
high
probability
acting
unique
(essentially
monophyletic)
presented,
together
additional
perspectives/considerations
treatment
this
‘very’
disease.
Journal of Internal Medicine,
Journal Year:
2023,
Volume and Issue:
294(5), P. 582 - 604
Published: July 10, 2023
Eating
behavior
and
food-related
decision
making
are
among
the
most
complex
of
motivated
behaviors,
understanding
neurobiology
eating
behavior,
its
developmental
dynamics,
is
critical
to
advancing
nutritional
sciences
public
health.
Recent
advances
from
both
human
animal
studies
revealing
that
individual
capacity
make
health-promoting
food
decisions
varies
based
on
biological
physiological
variation
in
signaling
pathways
regulate
homeostatic,
hedonic,
executive
functions;
past
exposures
current
life-stage;
environment;
complications
chronic
disease
reinforce
obese
state.
rate
drives
increased
calorie
intake
represents
an
important
opportunity
lower
rates
consumption
energy
through
product
reformulation.
Understanding
behaviors
nutrition
context
neuroscience
can
strengthen
evidence
base
which
dietary
guidelines
derived
inform
policies,
practices,
educational
programs
a
way
increases
likelihood
they
adopted
effective
for
reducing
obesity
other
diet-related
disease.
Acta Psychiatrica Scandinavica,
Journal Year:
2024,
Volume and Issue:
150(6), P. 516 - 529
Published: July 24, 2024
Managing
body
weight
in
patients
with
antipsychotic-induced
gain
(AIWG)
is
challenging.
Besides
lifestyle
interventions,
pharmacological
interventions
may
contribute
to
loss.
This
systematic
review
and
meta-analysis
evaluated
the
effect
on
loss
adverse
effects
of
glucagon-like
peptide-1
(GLP-1)
agonists
AIWG.
Nutrition Reviews,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 22, 2025
Abstract
The
purpose
of
the
present
narrative
review
was
to
propose
a
unifying
generalized
conceptual
model
mechanisms
and
processes
in
appetite
self-regulation
(ASR)
childhood.
Appetite
self-regulation,
along
with
other
domains
develops
across
childhood
contributes
energy
intake
balance,
diet
quality,
weight,
therefore
long-term
health
outcomes.
There
have
been
efforts
conceptualize
measure
components
ASR
associated
processes/mechanisms,
but,
at
present,
there
is
no
conceptualization
A
search
key
databases
supplemented
by
snowballing
undertaken
for
definitions/conceptions
theoretical
models
focus
on
children.
An
interpretive
synthesis
approach
used
identify
themes
from
definitions
models.
formed
basis
proposed
childhood,
which
main
contribution
article.
At
center
bottom-up
reactivity
food,
food
cues
hunger,
satiation
satiety
signals,
together
top-down
regulatory
control.
additional
5
interacting
overlapping
(biological,
hedonics,
cognitive,
behavioral,
traits)
that
function
influence
both
regulation.
also
contribute
outcomes
enactment
competence.
External
contextual
intrapersonal
factors
are
conceived
as
impacting
bottom-up,
processes.
relevance
explanations
phenomena
children’s
choice
well
its
implications
research
directions
approaches
preventive
intervention,
including
parenting
practices,
discussed.
provides
framework
researchers
practitioners
support
interpret
problems
competence
self-directing
choices,
intake,
nutrition.
Genes,
Journal Year:
2023,
Volume and Issue:
14(11), P. 2070 - 2070
Published: Nov. 13, 2023
Obesity
is
a
condition
that
characterized
by
the
presence
of
excessive
adipose
tissue
in
body.
has
become
one
main
health
concerns
worldwide
since
it
can
lead
to
other
chronic
ailments,
such
as
type
2
diabetes
or
fatty
liver
disease,
and
could
be
an
aggravating
factor
infections.
MicroRNAs
(miRNAs)
are
small,
non-coding
RNA
molecules
regulate
gene
expression
play
important
role
controlling
crucial
biological
processes
involved
onset
obesity,
lipogenesis,
adipogenesis,
lipid
metabolism,
regulation
cytokines
chemokines.
Moreover,
chemical
compounds
present
food
packaging
alter
miRNA
aforementioned
mechanisms
related
progression.
Furthermore,
therapies,
bariatric
surgery
aerobic
exercise
training,
also
influence
profile
miRNAs
obesity.
Therefore,
review
provides
insight
into
current
research
on
obesity
obesity-derived
intending
develop
novel
therapies
effectively
manage
these
disorders.
Cell Metabolism,
Journal Year:
2025,
Volume and Issue:
37(3), P. 606 - 615.e3
Published: March 1, 2025
The
carbohydrate-insulin
model
predicts
that
meals
with
varying
glycemic
indices
will
elicit
distinct
metabolic
and
hunger
responses,
including
greater
intake
at
subsequent
following
high-glycemic-index
meals.
To
test
this,
a
randomized
trial
(NCT05804942)
was
conducted
in
healthy
adults
using
intervention
low,
medium,
high
constant
macronutrient
composition.
After
of
the
meals,
glucose
insulin
followed
predicted
pattern,
but
subjective
did
not.
At
group
level,
low
index
led
to
lower
energy
changes.
individual
changes
were
unrelated
body
fatness
or
levels
glucose,
β-hydroxybutyrate,
free
fatty
acids,
L-lactate,
leptin,
adrenaline,
glucagon-like
peptide-1,
glucagon,
insulin-glucagon
ratio.
A
weak
negative
association
observed
between
ratio
300
min,
opposite
model's
prediction.
These
data
provide
little
support
for
model.
