Fish Physiology and Biochemistry,
Journal Year:
2023,
Volume and Issue:
50(2), P. 767 - 783
Published: Dec. 7, 2023
Abstract
In
the
aquaculture
industry,
silica
nanoparticles
(SiNPs)
have
great
significance,
mainly
for
confronting
diseases.
Therefore,
present
study
aims
to
assess
antibacterial
efficiency
of
SiNPs
as
a
versatile
trial
against
Aeromonas
veronii
infection
in
African
catfish
(
Clarias
gariepinus
).
Further,
we
investigated
influence
palliating
immune-antioxidant
stress
biochemical,
ethological,
and
histopathological
alterations
induced
by
A.
.
The
experiment
was
conducted
10
days,
about
120
fish
were
distributed
into
four
groups
at
random,
with
30
each.
first
group
is
control
that
neither
exposed
nor
SiNPs.
second
vulnerable
concentration
20
mg/L
water.
third
experimentally
infected
1.5
×
7
CFU/mL.
fourth
+
SiNPs)
Results
outlined
behavioral
suppression
responses
appeared
clear
decline
protein
profile
indices,
complement
3,
lysozyme
activity,
glutathione
peroxidase,
total
antioxidant
capacity.
kidney
liver
function
biomarkers
(creatinine,
urea,
alkaline
phosphatase,
alanine
aminotransferase)
lipid
peroxide
(malondialdehyde)
substantially
increased
group,
marked
changes
immunohistochemical
these
tissues.
Interestingly,
exposure
resulted
improvement
all
measured
noticeable
regeneration
changes.
Overall,
it
will
establish
are
new,
successful
tool
opposing
immunological,
antioxidant,
physiological,
infection.
Pharmaceutics,
Journal Year:
2024,
Volume and Issue:
16(9), P. 1114 - 1114
Published: Aug. 23, 2024
Nanobiotechnology,
at
the
intersection
of
nanotechnology
and
biology,
represents
a
burgeoning
field
poised
to
revolutionize
medicine
through
use
advanced
nanocarriers.
These
nanocarriers,
endowed
with
distinctive
physiobiological
attributes,
are
instrumental
in
diverse
therapeutic
domains
including
drug
delivery
for
microbial
infections,
cancer
treatment,
tissue
engineering,
immunotherapy,
gene
therapy.
Despite
transformative
potential,
several
challenges
hinder
their
efficacy,
such
as
limited
capacity,
suboptimal
targeting,
poor
solubility.
This
review
delves
into
latest
advancements
nanocarrier
technologies,
examining
properties,
associated
limitations,
innovative
solutions
developed
address
these
issues.
It
highlights
promising
systems
like
nanocomposites,
micelles,
hydrogels,
microneedles,
artificial
cells
that
employ
conjugation
techniques,
sustained
stimulus-responsive
release
mechanisms,
enhanced
By
exploring
novel
structures
contributions
overcoming
existing
barriers,
article
emphasizes
vital
role
interdisciplinary
research
advancing
nanobiotechnology.
offers
unparalleled
opportunities
precise
effective
delivery,
underscoring
its
potential
reshape
healthcare
personalized,
targeted
treatments
improved
performance.
Aquaculture International,
Journal Year:
2024,
Volume and Issue:
33(1)
Published: Nov. 13, 2024
Abstract
Immunostimulant
phytogenic
feed
additives
are
given
great
concern
for
improving
fish
health,
growth,
immune
responses,
and
resistance
to
diseases.
This
research
investigated
the
impact
of
dietary
propolis
(PRO),
turmeric
(TUR),
their
combination
on
hematology,
antioxidant-immune
regulating
genes
in
Nile
tilapia
(
Oreochromis
niloticus
)
during
Edwardsiella
tarda
challenge.
For
8
weeks,
a
total
number
320
(20.70
±
0.14
g)
were
allocated
into
four
groups
at
random,
each
with
eight
replicates
(10
each).
The
first
group
(1st)
was
basal
diet
(control)
without
any
supplements.
2nd,
3rd,
4th
supplemented
1%
PRO,
TUR,
mixture
(1%PRO
+
1%TUR),
respectively.
experimental
challenged
intraperitoneally
E.
dose
0.1
mL
(1
×
10
5
CFU)
termination
feeding
trial,
survival
estimated
an
additional
7
days.
results
demonstrated
that
fish-fed
diets
PRO
and/or
TUR
showed
higher
body
weight,
condition
factor,
specific
growth
rate,
intake,
efficiency
utilization
than
control
P
<
0.05).
hematological,
protein
profile,
(total
antioxidant
capacity,
lysozymes,
IgM)
parameters
substantially
improved
fed
compared
non-fed
fish.
lipid
profile
malondialdehyde
decreased
group.
Notably,
down-turning
nuclear
factor
kappa
B
NFκB
tumor
necrosis
factor-alpha
TNF-α
expression
up-turning
erythroid
2-related
2
Nrf2
transforming
factor-beta
TGF-β
noticed
Noteworthy,
can
be
added
enhance
response,
.
These
outcomes
help
sustainable
development
culture
industry.
Graphical
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Feb. 23, 2024
Abstract
The
potential
use
of
feed
supplements
as
immune-stimulant
and
growth-promoting
agents
in
fish
diets
has
drawn
a
lot
attention.
current
research
investigated
the
effects
feeding
Nile
tilapia
(Oreochromis
niloticus)
on
white
poplar
(Populus
alba
L.)
leaves
powder
(WP)
dietary
supplement
growth,
digestive
functions,
immne-antioxidant
parameters.
In
addition,
resistance
against
Aeromonas
sobria
challenge
was
investigated.
For
60
days,
(n
=
160;
34.61
±
0.16
g)
were
divided
equally
into
four
groups,
each
had
replicates.
Fish
fed
supplemented
with
varying
levels
WP;
0
g/kg
(WP0),
2
(WP2),
4
(WP4),
6
(WP6),
where
WP0
control
diet.
results
revealed
that
WP
(2–6
level)
substantially
boosted
growth
(final
body
weight,
weight
gain,
specific
rate
%,
improvement
conversion
ratio)
tilapia.
improved
amylase
(4–6
lipase
activity
intestinal
morphometric
measures
level).
increased
hormone
reduced
leptin
glucose
immune-antioxidant
indices
(total
protein,
albumin,
globulin,
complement
3,
lysozymes,
nitric
oxide,
total
antioxidant
capacity,
glutathione
peroxidase,
catalase)
significantly
by
survival
%
level
dependent
manner
compared
to
(WP0)
during
A.
challenge.
Noteworthy,
especially
at
6g/kg
could
be
used
for
improving
health,
disease
Fish Physiology and Biochemistry,
Journal Year:
2023,
Volume and Issue:
50(2), P. 767 - 783
Published: Dec. 7, 2023
Abstract
In
the
aquaculture
industry,
silica
nanoparticles
(SiNPs)
have
great
significance,
mainly
for
confronting
diseases.
Therefore,
present
study
aims
to
assess
antibacterial
efficiency
of
SiNPs
as
a
versatile
trial
against
Aeromonas
veronii
infection
in
African
catfish
(
Clarias
gariepinus
).
Further,
we
investigated
influence
palliating
immune-antioxidant
stress
biochemical,
ethological,
and
histopathological
alterations
induced
by
A.
.
The
experiment
was
conducted
10
days,
about
120
fish
were
distributed
into
four
groups
at
random,
with
30
each.
first
group
is
control
that
neither
exposed
nor
SiNPs.
second
vulnerable
concentration
20
mg/L
water.
third
experimentally
infected
1.5
×
7
CFU/mL.
fourth
+
SiNPs)
Results
outlined
behavioral
suppression
responses
appeared
clear
decline
protein
profile
indices,
complement
3,
lysozyme
activity,
glutathione
peroxidase,
total
antioxidant
capacity.
kidney
liver
function
biomarkers
(creatinine,
urea,
alkaline
phosphatase,
alanine
aminotransferase)
lipid
peroxide
(malondialdehyde)
substantially
increased
group,
marked
changes
immunohistochemical
these
tissues.
Interestingly,
exposure
resulted
improvement
all
measured
noticeable
regeneration
changes.
Overall,
it
will
establish
are
new,
successful
tool
opposing
immunological,
antioxidant,
physiological,
infection.
