Sex-biased gene expression precedes sexual dimorphism in the agonadal annelidPlatynereis dumerilii DOI Creative Commons
Rannyele Passos Ribeiro, Ryan W. Null, B. Duygu Özpolat

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: June 13, 2024

Gametogenesis is the process by which germ cells differentiate into mature sperm and oocytes, essential for sexual reproduction. The sex-specific molecular programs that drive spermatogenesis oogenesis can also serve as sex identification markers. Platynereis dumerilii a research organism has been studied in many areas of developmental biology. However investigations often disregard sex, P. juveniles lack dimorphism. mechanisms gametogenesis segmented worm are largely unknown. In this study, we used RNA sequencing to investigate transcriptomic profiles juveniles. Our analysis revealed sex-biased gene expression becomes increasingly pronounced during advanced stages, particularly meiotic phases gametogenesis. We identified conserved genes associated with spermatogenesis, such dmrt1, novel psmt, oogenesis. Additionally, putative long non-coding RNAs were upregulated both male female gametogenic programs. This study provides foundational resource cell dumerilii, markers identification, offers comparative data enhance our understanding evolution across species.

Language: Английский

Sex-biased gene expression precedes sexual dimorphism in the agonadal annelidPlatynereis dumerilii DOI Creative Commons
Rannyele Passos Ribeiro, Ryan W. Null, B. Duygu Özpolat

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: June 13, 2024

Gametogenesis is the process by which germ cells differentiate into mature sperm and oocytes, essential for sexual reproduction. The sex-specific molecular programs that drive spermatogenesis oogenesis can also serve as sex identification markers. Platynereis dumerilii a research organism has been studied in many areas of developmental biology. However investigations often disregard sex, P. juveniles lack dimorphism. mechanisms gametogenesis segmented worm are largely unknown. In this study, we used RNA sequencing to investigate transcriptomic profiles juveniles. Our analysis revealed sex-biased gene expression becomes increasingly pronounced during advanced stages, particularly meiotic phases gametogenesis. We identified conserved genes associated with spermatogenesis, such dmrt1, novel psmt, oogenesis. Additionally, putative long non-coding RNAs were upregulated both male female gametogenic programs. This study provides foundational resource cell dumerilii, markers identification, offers comparative data enhance our understanding evolution across species.

Language: Английский

Citations

2