Dietary retinoic acid improved the growth, lipid metabolism and immune status in Macrobrachium rosenbergii DOI Creative Commons
Qincheng Huang, Li Wang, Zhimin Gu

et al.

Frontiers in Marine Science, Journal Year: 2025, Volume and Issue: 12

Published: March 27, 2025

The effect of dietary retinoic acid (RA) on the growth, lipid deposition, oxidation resistance, immunity, hepatopancreatic and intestinal health Macrobrachium rosenbergii was evaluated. A total 1200 prawns (0.22 ± 0.00 g) were divided into six groups fed their corresponding feed containing 4, 132, 296, 562, 1206 or 2562 mg/kg RA. weight gain rate, specific growth rate final body changed linearly quadratically, with maximum observed in those 296 Increasing RA quadratically raised content whole body. Compared to 4 RA, there significantly lower deposition muscle, hepatopancreas Prawns had triglyceride (TG) upregulated gene expression retinoid X receptor ( RXR ), diacylglycerol acyltransferase 1 dgat1 ) carnitine palmitoyltransferase cpt1 ). Additionally, increased protein RXR, CAMKKβ phospho-AMPK. level could decrease oxidative stress by upregulating peroxiredoxin 5 prx5 improve immunity toll - like 2 toll2 myeloid differentiation factor 88 (myd88 dosal hepatopancreas. related genes crustin / 3 , anti-lipopolysaccharide 7 peritrophin-1 myosin light chain kinase claudin myd88 morphological structure also positively affected Furthermore, relieve immune responses induced lipopolysaccharide, thus leading transcription antimicrobial peptides. In summary, utilisation, antioxidant capacity M . To avoid negative effects excessive addition obtain optimal a diet suggested present study.

Language: Английский

Dietary retinoic acid improved the growth, lipid metabolism and immune status in Macrobrachium rosenbergii DOI Creative Commons
Qincheng Huang, Li Wang, Zhimin Gu

et al.

Frontiers in Marine Science, Journal Year: 2025, Volume and Issue: 12

Published: March 27, 2025

The effect of dietary retinoic acid (RA) on the growth, lipid deposition, oxidation resistance, immunity, hepatopancreatic and intestinal health Macrobrachium rosenbergii was evaluated. A total 1200 prawns (0.22 ± 0.00 g) were divided into six groups fed their corresponding feed containing 4, 132, 296, 562, 1206 or 2562 mg/kg RA. weight gain rate, specific growth rate final body changed linearly quadratically, with maximum observed in those 296 Increasing RA quadratically raised content whole body. Compared to 4 RA, there significantly lower deposition muscle, hepatopancreas Prawns had triglyceride (TG) upregulated gene expression retinoid X receptor ( RXR ), diacylglycerol acyltransferase 1 dgat1 ) carnitine palmitoyltransferase cpt1 ). Additionally, increased protein RXR, CAMKKβ phospho-AMPK. level could decrease oxidative stress by upregulating peroxiredoxin 5 prx5 improve immunity toll - like 2 toll2 myeloid differentiation factor 88 (myd88 dosal hepatopancreas. related genes crustin / 3 , anti-lipopolysaccharide 7 peritrophin-1 myosin light chain kinase claudin myd88 morphological structure also positively affected Furthermore, relieve immune responses induced lipopolysaccharide, thus leading transcription antimicrobial peptides. In summary, utilisation, antioxidant capacity M . To avoid negative effects excessive addition obtain optimal a diet suggested present study.

Language: Английский

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