Melatonin and resveratrol alleviate molecular and metabolic toxicity induced by Bisphenol A in endometrial organoids

Reproductive Toxicology, Journal Year: 2024, Volume and Issue: 128, P. 108628 - 108628

Published: June 5, 2024

Bisphenol A (BPA), a widespread environmental contaminant, poses concerns due to its disruptive effects on physiological functions of the uterine endometrium. In contrast, melatonin (MT) and Resveratrol (RSV) are under scrutiny for their potential protective roles against BPA-induced damage. For efficacy ethical in animal test, endometrial organoids, three-dimensional models mimicking endometrium, serve as crucial tools unraveling impact factors reproductive health. This study aimed comprehensively characterize morphological, molecular metabolic responses porcine organoids BPA assess MT RSV. Porcine uteri were prepared, digested with collagenase, mixed Matrigel, incubated at 38°C 5 % CO

Language: Английский

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Modeling Lamotrigine-Induced Reprotoxicity in Porcine Endometrial Organoids: Integrated Multi-platform Profiling

Reproductive Toxicology, Journal Year: 2025, Volume and Issue: unknown, P. 108926 - 108926

Published: April 1, 2025

Language: Английский

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Rhodobacter sphaeroides supplementation improves defense ability of Chinese mitten crab Eriocheir sinensis against Shewanella putrefaciens infection via intestinal flora and metabolism regulation

Journal of Invertebrate Pathology, Journal Year: 2024, Volume and Issue: 204, P. 108120 - 108120

Published: April 27, 2024

Language: Английский

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Microplastics occurrence in sea cucumbers and impacts on sea cucumbers & human health: A systematic review

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 951, P. 175792 - 175792

Published: Aug. 26, 2024

Language: Английский

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