Imidazolium‐dithiocarboxylate zwitterions catalysed ring‐opening additions of cyclopropenones

Advanced Synthesis & Catalysis, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 23, 2025

Abstract Imidazolium‐dithiocarboxylate zwitterions (NHC ⋅ CS 2 ), a novel organocatalyst that derived from N‐heterocyclic carbene (NHC), was used to activate cyclopropenones. Under the catalysis of 10 mol% NHC 2, range phenols, alcohols, primary and secondary amines react with cyclopropenones produce trisubstituted α , β ‐unsaturated esters amides in 46–95% yield. More than 68 products, including 7 natural product derivatives have been synthesized through this method. Mechanism study showed act as Lewis base C=C double bond trigger ring‐opening reaction. HRMS analysis indicated formation key adduct cyclopropenone. importantly, demonstrated completely different catalytic activity catalysts, latter one cannot catalyse these reactions.

Language: Английский

Synthesis of thiopyran derivatives via [4 + 2] cycloaddition reactions

RSC Advances, Journal Year: 2025, Volume and Issue: 15(14), P. 11160 - 11188

Published: Jan. 1, 2025

In this review, we provide a comprehensive overview of the synthesis thiopyran family compounds via cycloaddition reactions, with examples spanning from year 2000 to present.

Language: Английский

Room temperature natural light promoted DMSO/O2-catalyzed N-acylation reaction of imidazoles/triazoles with cyclopropenones

Molecular Diversity, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 25, 2024

Language: Английский