Potentially inappropriate medications for geriatric patients in Bahrain: prevalence, predictors, and implications for practice

BMC Geriatrics, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 10, 2025

The global increase in the older adult population necessitates a comprehensive understanding of medication management to mitigate risks associated with potentially inappropriate medications (PIMs). These are particular concern due their association adverse drug reactions, increased hospitalization, and healthcare costs. This study aimed determine prevalence risk factors PIM use among patients attending primary health care centers Bahrain. cross-sectional was conducted 2022 27 across included aged 65 years or older. A computer based simple random sample obtained, Beers criteria 2023 utilized assess appropriateness. Anonymous data retrieved from electronic medical records analyzed via univariate, logistic regression analyses. Among 595 studied, average age 71.7 years, 54.5% (n = 324) being female. Most were married (70.8%, n 421). More than half (51.3%, 305) received at least one PIM, gliclazide (37%, 113), pantoprazole (29.8%, 91), rabeprazole (27.9%, 85) most prevalent prescribed PIM. Univariate analyses revealed that rates significantly higher females (p 0.001) comorbidities such as diabetes mellitus < 0.001), essential hypertension hyperlipidaemia 0.001). Logistic analysis (OR 1.09, p female sex 1.645, 0.012), 1.696, 0.029) significant predictors use. highlights burden Bahrain, more participants receiving findings underscore urgent need for targeted interventions, particularly patients, those chronic conditions mellitus, taking five medications. insights contribute broader geriatric pharmacotherapy offer foundation policy development optimizing safety aging populations.

Language: Английский

Inappropriate Medications Use and Polypharmacy among Older Adults with Anxiety Disorder

Journal of Clinical Medicine, Journal Year: 2023, Volume and Issue: 12(13), P. 4195 - 4195

Published: June 21, 2023

Background: Elderly with mental health conditions usually use multiple medications, which predisposes them to inappropriate of is defined as medications that should be avoided due their risk; this outweighs benefit given safer alternatives are available. This study aimed examine potentially medication among older patients anxiety disorder. Methods: used a cross-sectional retrospective design using twelve months data extracted from the Electronic Health Record (EHR) database for adults diagnosed disorder and treated in ambulatory care setting. Potentially (PIMs) was evaluated 2019 Beers criteria. Descriptive statistics were describe sample. Pearson’s chi-square tests (for categorical variables) t-tests continuous utilized measure differences independent variables between without PIMs. Binary logistic regression associations PIMs identify potential factors Analyses performed Statistical Analysis Software version 9.4 (SAS® 9.4). Results: The sample includes 371 (age ≥ 65 years) disorder; average age (72.1 ± 5.8) years. highly prevalent (66.6%). About 35.6% one PIM, 22.6% two PIMs, 8.4% three most frequently prescribed NSAIDs gastrointestinal agents. adjusted analysis found less likely men than women. In addition, more women diabetes, cancer, polypharmacy. Conclusions: Future studies on strategies interventions rationing necessary high prevalence polypharmacy within population.

Language: Английский