The Current Status of Frailty and Influencing Factors in Elderly Patients With Hip Fractures: A Meta‐Analysis

BioMed Research International, Journal Year: 2025, Volume and Issue: 2025(1)

Published: Jan. 1, 2025

Background: Hip fractures have emerged as a significant health risk, posing substantial threat to the well-being and longevity of elderly population. The occurrence postoperative complications frailty profoundly impacts quality life in these individuals. This meta-analysis is aimed at elucidating present scenario clarifying current status influencing factors hip fracture patients. findings will serve solid evidence for formulating effective scientific strategies prevent this vulnerable patient group. Methods: databases, including PubMed, Cochrane Library, Embase, were utilized from February 2003 2023, using keywords frailty, elderly, identify systematic reviews or meta-analyses. primary randomized clinical trials included meta-analyses identified. Two independent authors assessed all eligible studies. Statistical analyses evaluated Review Manager (RevMan) Version 5.3. Results: Of 15 studies out 352 identified studies, 12 cross-sectional research 2 case-control 1 cohort study confirmed. There 3475 patients, 1209 them showed with 41% incidence 18 influence determined. A marked between-study heterogeneity (I = 95%, p < 0.00001) was examined. Factors patients age (odds ratio (OR) 2.73, 95% confidence interval (CI): 2.12~3.53), comorbidity (OR 4.20, CI: 2.31~7.62), duration bed rest 2.22, 1.54~3.18), nutritional 1.62, 1.21~2.17), self-perceived 3.53, 2.09~5.94). no publication bias, pooled results stable basing on sensitivity analysis. Conclusion: Frailty associated variety consisting age, conditions, extended periods rest, status, high comorbid poor advanced status.

Language: Английский

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Association between estimated pulse wave velocity and hip fracture in middle-aged and older adults: A prospective cohort study in China

Bone, Journal Year: 2025, Volume and Issue: unknown, P. 117499 - 117499

Published: April 1, 2025

Language: Английский

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Association between possible sarcopenia, all-cause mortality, and adverse health outcomes in community-dwelling older adults in China

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Oct. 29, 2024

The relationship between possible sarcopenia and mortality remains ambiguous within Asian populations. To clarify this, we investigated the association in older adults residing Chinese communities. Utilizing data from China Health Retirement Longitudinal Study, this population-based cohort study included individuals aged ≥ 60 years, followed 2011 to 2012 through 2020. Possible was defined accordance with Working Group on Sarcopenia 2019 criteria, Cox proportional hazards regression used analyze its impact mortality, while exploratory analyses were conducted investigate associations of chronic diseases, functional independence, hospitalization frequency. encompassed 5,160 participants (median age: 66 years), nearly half whom (48.8%) identified sarcopenia. Over a 9-year follow-up period, there 1216 recorded deaths. Analysis indicated that faced significantly elevated risk compared their counterparts (HR: 1.79, 95% CI: 1.58-2.03; P < 0.001). Further, subgroup confirmed strong all-cause across various subgroups, including those related sex, obesity status, living environment. Additionally, revealed associated an increased likelihood heart disease (OR = 1.18, 1.03-1.34, 0.014) stroke 1.41, 1.19-1.68, 0.001), as well reduced independence (β -0.17, -0.24--0.10, also higher frequency hospitalizations at baseline (Exp(β) 1.50, 1.25-1.81, although no longer significant during period. In conclusion, community-dwelling adults, several dependence. Thus, alleviating or preventing may improve health outcomes extend lifespan these individuals.

Language: Английский

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Plant proteins: are they a good alternative to animal proteins in older people?

Current Opinion in Clinical Nutrition & Metabolic Care, Journal Year: 2024, Volume and Issue: 27(4), P. 372 - 377

Published: March 1, 2024

Purpose of review This provides the latest insight into impact consuming plant-based protein for older people. Recent findings According to data, a healthy diet rich in plant-based-protein-rich-food could promote aging. health effect is partly because amino acid composition proteins, as well important constituents such fiber and bioactive compounds found matrix. Furthermore, even though animal more effective at stimulating muscle synthesis, high consumption plant (beyond 31 g/day) appears enhance physical performance reduce risk frailty individuals. Summary literature highlights numerous benefits people associated with substantial intake vs. animal-based protein, both preventing mitigating chronic age-related diseases reducing all-cause mortality. However, protein-rich products pose risks malnutrition fiber-related intestinal intolerances. Further research needed assess risk–benefit ratio proteins individuals before we can make robust recommendations on how far be healthfully replaced proteins.

Language: Английский

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