Hypothetical Behavioral Interventions for Mitigating the Cardiovascular Effects of Long‐Term Fine Particulate Matter Exposure: Analyses From 2 Prospective Cohorts

Journal of the American Heart Association, Journal Year: 2025, Volume and Issue: unknown

Published: March 13, 2025

Background Whether healthy behaviors can attenuate the adverse association between ambient fine particulate matter (PM 2.5 ) and cardiovascular disease (CVD) is inconclusive. METHODS AND RESULTS The parametric g‐formula was used to quantify potential reduction in PM effect on CVD under different scenarios of hypothetical behavioral interventions (including dietary patterns, physical activity, body mass index, alcohol consumption, smoking, supplements). Feasible intervention scenarios, defined basis values considered feasible previous real‐world (eg, overweight participants lose 6.69% their weight). Intensive which all are adopting completely maintain normal We also estimate joint that incorporate above behaviors. Long‐term exposure associated with incident both cohorts, risk difference per 1000 person‐years for a 5 μg/m 3 increase being 1.42 (95% CI, 1.04–1.79) UKB (UK Biobank) 2.15 1.65–2.59) Sichuan Cohort (China Multi‐Ethnic Cohort, Region). In intensive improving diet, index could significantly reduce CVD, reduced proportion ranging from 4.59% 37.22%. A 6 would by 31.47% (10.13%–57.26%) 19.75% (10.78%–42.89%) low‐pollution UK Biobank high‐pollution cohort, respectively. combination more 57.51% (21.64%–100.69%) 45.54% (22.66%–106.66%), Conclusions Healthier serve as individual‐level complementary strategies emission control minimizing health impact , whether high‐ or areas.

Language: Английский

Other musculoskeletal disorders in China, 1990–2021, and projections to 2050: findings from the Global Burden of Disease Study 2021

Clinical Rheumatology, Journal Year: 2025, Volume and Issue: unknown

Published: April 29, 2025

Language: Английский