The Unique Immune System of Bats: An Evolutionary Analysis and Bibliometric Study DOI Creative Commons
Rui Li,

Wenliang Zhao,

Apeng Chen

et al.

Ecology and Evolution, Journal Year: 2024, Volume and Issue: 14(11)

Published: Nov. 1, 2024

Bats exhibit a greater capacity to tolerate diverse viruses than other terrestrial mammals. To address these questions, we utilized evolutionary and bibliometric analyses explore the immunological characteristics of bats identify contemporary research hotspots in bat immunity. investigate historical interactions between viral infections, used tBLASTn software integrated endogenous retroviruses within genomes nine species seven elucidate immune bats, OrthoFinder, CAFE, Gene Ontology phylogenetic trees homologous genes, expanded/contracted gene families, associated signaling pathways 28 mammalian genomes. We also analysis "immune system bats" deepen our understanding mechanisms bats. Significant integrations Gammaretroviruses, Spumaretroviruses, Deltaretroviruses were observed Notable expansions families included Type III interferon, heat-shock protein 90 (HSP90), members tumor necrosis factor receptor superfamily (TNFRSF). These expanded are involved related "transcription replication influenza virus RNA," "COVID-19-related pathways," "positive regulation phosphorylation." contractions "type I interferon" "antibody-related families." Bibliometric further underscored several significance critical such as HSP90, TNF. The exploration revealed two predominant themes: "efficient varied antiviral responses" "dampened inflammation prevent excessive inflammatory reactions," thereby elucidating underlying adaptations Through analyses, identified genes Currently, on primarily focuses themes "inflammation suppression."

Language: Английский

A decline in financial literacy potentially associated with the development of neuropsychiatric symptoms: a case report DOI Open Access
Ryota Kobayashi, Kazutaka Sakamoto, Daichi Morioka

et al.

Psychogeriatrics, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 1, 2025

All data generated or analyzed during this study are included in published article.

Language: Английский

Citations

0
Deciphering the Functions of Raphe–Hippocampal Serotonergic and Glutamatergic Circuits and their Deficits in Alzheimer’s Disease DOI Open Access
Wanting Yu, R Zhang,

Aosheng Zhang

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(3), P. 1234 - 1234

Published: Jan. 30, 2025

Subcortical innervation of the hippocampus by raphe nucleus is essential for emotional and cognitive control. The two major afferents from to originate serotonergic glutamatergic neurons, which control hippocampal inhibitory network, theta activity, synaptic plasticity have been extensively explored in growing body literature, whereas those circuits received little attention. Notably, both between are disrupted Alzheimer's disease (AD), may contribute initiation progression behavioral psychological symptoms dementia. Thus, deciphering mechanism underlying abnormal raphe-hippocampal AD crucial prevent dementia-associated symptoms. In this review, we summarize anatomical, neurochemical, electrophysiological diversity nuclei as well architecture circuitry. We then elucidate subcortical activity their role regulation emotion cognition. Additionally, present an overview pathogenesis analyze available therapies that can potentially be used clinically alleviate neuropsychiatric decline course.

Language: Английский

Citations

0
Minimal hepatic encephalopathy: a bibliometric analysis (1999–2023) DOI

Chao Ju,

Longtao Yang, Xuemei Wang

et al.

Current Psychology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 19, 2025

Language: Английский

Citations

0
Insights into the history and trends of nanotechnology for the treatment of hepatocellular carcinoma: a bibliometric-based visual analysis DOI Creative Commons

Yulei Zhao,

Xingxin Wang,

Xiaoman Yang

et al.

Discover Oncology, Journal Year: 2025, Volume and Issue: 16(1)

Published: April 7, 2025

Language: Английский

Citations

0
Artificial intelligence-assisted multimodal imaging for the clinical applications of breast cancer: a bibliometric analysis DOI Creative Commons
Chang Hou, Ting Huang, Keke Hu

et al.

Discover Oncology, Journal Year: 2025, Volume and Issue: 16(1)

Published: April 16, 2025

Language: Английский

Citations

0
Machine learning applied to mild cognitive impairment: bibliometric and visual analysis from 2015 to 2024 DOI Creative Commons
Huan Liu,

Qing Huo,

Feng Li

et al.

Frontiers in Neurology, Journal Year: 2025, Volume and Issue: 16

Published: May 21, 2025

Background At present, the world is in background of severe aging population challenges. Mild cognitive impairment (MCI), an intermediate state between normal and dementia, a syndrome impairment. Early recognition intervention MCI have great value for delaying decline function improving quality life elderly. Machine learning (ML) core sub-branch direction field artificial intelligence. In recent years, evaluating potential application machine medicine has been popular, including mild However, there currently no bibliometrics to evaluate scientific advances this field. Objective This study aims visually analyze current research trends regarding through bibliometry visualization techniques. Methods Using Web Science Core Collection database (Wo SCC), relevant articles reviews collection 2015–2024. Subsequently, collected papers were subjected bibliometric analysis utilizing CiteSpace, VOSviewer, “bibliometric” package R language. Results A total 2056 related patients with retrieved from Wo SCC database. The number increasing year by year. These are mainly 9,577 organizations 498 countries, most which United States China. journal largest publications FRONTIERS IN AGING NEUROSCIENCE. Folstein M authoritative author Johns Hopkins University School Medicine. His paper “Mini-mental state: practical method grading clinician” cited article Literature keyword indicate that prediction, automated monitoring MCI, continuous evaluation remote individuals interdisciplinary data integration personalized hotspots development directions. Conclusion first use methods visualize revealing frontiers information will provide useful reference researchers focusing on applications MCI.

Language: Английский

Citations

0
The ‘whole landscape’ of research on systemic sclerosis over the past 73 years DOI
Meng‐Di Zhang, Wan‐Ying Huang, Jia‐Yuan Luo

et al.

Autoimmunity Reviews, Journal Year: 2024, Volume and Issue: 23(5), P. 103538 - 103538

Published: March 29, 2024

Language: Английский

Citations

3
Visual trends and hot research on the relationship between intestinal microbiota and major lipids: a bibliometric analysis DOI Creative Commons
Weiming Sun,

Keqi Wan,

Jiawei Gui

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: April 30, 2024

The association between intestinal microbiota and lipids has garnered significant scholarly interest. This study analyzes pertinent literature on to offer scientific guidance for future advancements research directions. Articles focusing were obtained from the Web of Science Core Collection (WoSCC). Following a rigorous screening process, 12,693 articles included in study. collected data was processed comprehensively visually analyzed using various academic tools such as CiteSpace, VOSviewer, R software, Scimago Graphica. field its relationship with major witnessed surge attention, indicated by upward trend observed related articles. Among countries, China had emerged leading contributor publication output, Chinese Acad Sci being most prolific institution this field. Notably, Nutrients Nature prominent journals that published many highest number co-citations. Scholars have widely recognized Patrice D Cani's notable contributions Current endeavors focused obesity, insulin resistance, metabolism, growth performance, gut-brain axis, others. Our analysis identified four primary trends: "biochemical pathways," "exploration diseases," "intervention effect," "health diet." Future scholars must devote more attention advance our understanding human health.

Language: Английский

Citations

1
Neurocognitive Features of Mild Cognitive Impairment and Distress Symptoms in Older Adults Without Major Depression. DOI
Gallayaporn Nantachai,

Michael Maes,

Vinh-Long Tran-Chi

et al.

PubMed, Journal Year: 2024, Volume and Issue: 19, P. 1445 - 1459

Published: Jan. 1, 2024

Two distinct symptom dimensions were identified in older adults who did not have major depressive disorder (MDD): a) a dimension associated with mild cognitive dysfunction, and b) related to distress symptoms of old age (DSOA). It is uncertain whether previous findings regarding the features amnestic impairment (aMCI) remain valid when patients MDD are excluded.

Language: Английский

Citations

1
Mapping the evolution of liver aging research: A bibliometric analysis DOI

Qunhua Han,

Shiqing Huang,

Shasha Wu

et al.

World Journal of Gastroenterology, Journal Year: 2024, Volume and Issue: 30(41), P. 4461 - 4480

Published: Oct. 23, 2024

BACKGROUND With the increasing of global aging population, healthy and prevention age-related diseases have become increasingly important. The liver, a vital organ involved in metabolism, detoxification, digestion, immunity, holds pivotal role process organisms. Although extensive research on liver has been carried out, no bibliometric analysis conducted to evaluate scientific progress this area. AIM To analyze basic knowledge, development trends, current frontiers field via methods. METHODS We analyses range analytical tools including Python, bibliometrix package R, CiteSpace, VOSviewer. retrieved publication data from Web Science Core Collection Database. A knowledge map was constructed display contributions different authors, journals, countries, institutions, as well patterns co-occurrence keywords co-cited references. Additionally, gene regulation pathways associated with were analyzed STRING database. RESULTS identified 4288 articles aging, authored by 24034 contributors 4092 institutions across 85 countries. Notably, years 1991 2020 presented significant bursts output. United States led terms publications (n = 1008, 25.1%), citations 55205), international collaborations (multiple country 214). Keywords such “lipid metabolism”, “fatty disease”, “inflammation”, “liver fibrosis” “target” prominent, highlighting hotspots. top 64 genes, each which appeared at least 8 articles, essential for cell survival phosphatidylinositol 3-kinase/protein kinase B, Forkhead box O p53 signaling pathways. CONCLUSION This study highlights key areas offers comprehensive overview insights into potential value collaborative pursuits clinical implementations.

Language: Английский

Citations

1