Effects of home-based interventions on cognitive performance in patients with dementia: A systematic review and meta-analysis

Journal of Alzheimer s Disease, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 12, 2025

Background With increasing age, dementia is a common disease in the elderly population，especially Alzheimer's disease. Owing to nature of disease, function patients deteriorates, which places heavy burden on country and family. Home-based training programs have been shown improve cognitive with dementia. Objective To examine effects methods home-based interventions performance Methods This systematic review meta-analysis was conducted basis PRISMA statement. protocol registered advance at PROSPERO (CRD42021277269). Six English electronic databases, including PubMed, EMBASE, Cochrane Library, Web Science, SCOPUS, OTseeker, were searched updated January 31, 2024. Two researchers independently completed literature retrieval data extraction. RevMan 5.3 software used analyze data. The standardized mean difference 95% confidence interval for statistical analysis. Subgroup analyses performed by assessment tools, intervention duration methods. Results Twenty randomized controlled trials 3543 participants included qualitative synthesis, 17 studies meta-analysis. Compared control intervention, significantly improved (SMD = 0.45; CI [0.17, 0.74]; p 0.002). Conclusions Moderate high evidence shows that dementia, especially their comprehensive function.

Language: Английский

Effects of exercise interventions on cognitive function in patients with cognitive dysfunction: an umbrella review of meta-analyses

Frontiers in Aging Neuroscience, Journal Year: 2025, Volume and Issue: 17

Published: May 16, 2025

Objective This umbrella review assessed the quality, potential biases, and effects of exercise interventions on cognitive function in individuals with impairments. Methods A comprehensive meta-analyses randomized controlled trials (RCTs) was performed to evaluate Databases including Web Science, PubMed, Embase, Cochrane Database Systematic Reviews were searched. Outcomes evaluated using Grading Recommendations, Assessment, Development Evaluation (GRADE) system, classified as “high,” “moderate,” “low,” or “very low” quality. Results total 55 included, covering dementia, impairment, MCI, Alzheimer’s disease (AD), Parkinson’s (PD), stroke. Cognitive outcomes scales like MMSE MoCA. High-quality evidence supports Exergaming (SMD 0.69), Tai Chi 0.36), traditional Chinese mind–body exercises 0.32) for improving MoCA Score MCI patients. For moderate-quality shows resistance training 0.60) 0.27) have positive effects. Aerobic (MD 2.95) more effective AD, while 1.68) benefitted PD Multi-component 0.67) improved scores post-stroke impairment. unspecified impairments, combining showed higher effectiveness. Due small sample sizes, all findings Class IV evidence, requiring further research. Conclusion Moderate high-quality Exergaming, Chi, MCI. are effective; aerobic exercise; PD, exercises; multi-component beneficial. registration https://www.crd.york.ac.uk/PROSPERO/view/CRD42024587635 , identifier [CRD42024587635].

Language: Английский

Comparison of the effect of online physical exercise and computerized cognitive stimulation in patients with Alzheimer's disease during the Covid-19 pandemic

Complementary Therapies in Clinical Practice, Journal Year: 2024, Volume and Issue: 57, P. 101881 - 101881

Published: July 1, 2024

Language: Английский