International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(19), P. 10757 - 10757
Published: Oct. 6, 2024
With
the
aging
of
global
population,
neurodegenerative
diseases
are
emerging
as
a
major
public
health
issue.
The
adoption
less
sedentary
lifestyle
has
been
shown
to
have
beneficial
effect
on
cognitive
decline,
but
molecular
mechanisms
responsible
clear.
Here
we
provide
detailed
analysis
complex
molecular,
cellular,
and
systemic
underlying
age-related
decline
how
choices
influence
these
processes.
A
review
evidence
from
animal
models,
human
studies,
postmortem
analyses
emphasizes
importance
integrating
physical
exercise
with
cognitive,
multisensory,
motor
stimulation
part
multifaceted
approach
mitigating
decline.
We
highlight
potential
non-pharmacological
interventions
address
key
hallmarks,
such
genomic
instability,
telomere
attrition,
neuroinflammation,
underscore
need
for
comprehensive
personalized
strategies
promote
resilience
healthy
aging.
GeroScience,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 12, 2025
Abstract
Sleep
duration
is
a
crucial
factor
influencing
health
outcomes,
yet
its
relationship
with
mortality
remains
debated.
In
this
meta-analysis,
we
aimed
to
investigate
the
association
between
short
and
long
sleep
all-cause
in
adults,
including
sex-specific
differences.
A
systematic
search
was
performed
multiple
databases,
PubMed,
Cochrane
Central,
Web
of
Science,
up
October
2024.
Retrospective
prospective
cohort
studies
involving
adults
at
least
1
year
follow-up
data
on
were
included.
Hazard
ratios
pooled
using
random-effects
model,
subgroup
analyses
based
sex
categories.
total
79
included,
stratified
by
categorized
into
durations.
Short
(<
7
h
per
night)
associated
14%
increase
risk
compared
reference
7–8
h,
hazard
ratio
1.14
(95%
CI
1.10
1.18).
Conversely,
(≥
9
34%
higher
mortality,
1.34
1.26
1.42).
Sex-specific
indicated
that
both
durations
significantly
elevated
men
women,
although
effect
more
pronounced
for
women.
Both
are
increased
though
degree
varies
sex.
These
findings
underscore
importance
considering
optimal
public
strategies
enhancing
longevity
highlight
need
approaches
research.
Comprehensive Psychiatry,
Journal Year:
2025,
Volume and Issue:
139, P. 152591 - 152591
Published: March 14, 2025
The
COVID-19
pandemic
seriously
impacted
people's
lifestyles,
leading
to
changes
in
physical
activity,
sleep
and
mental
health.
This
study
aimed
assess
the
recovery
of
these
indicators
Chinese
university
students
post-COVID-19
pandemic,
explore
association
between
lifestyle
psychological
problems.
A
two-wave
longitudinal
was
conducted
with
2,748
college
Hebei,
China.
Self-report
questionnaires
measured
variables
(depression
symptoms,
anxiety
perceived
stress)
2022
2024.
McNemar
chi-square
test
compared
differences
two
waves.
Additionally,
univariate
multivariate
logistic
regression
analyses
were
performed
examine
independent
joint
associations
behaviors
problems
across
this
period.
Proportion
inactivity
decreased
from
22.5%
16.2%,
poor
quality
reduced
18.3%
16.2%
after
(P
<
0.05).
Depression
symptoms
also
improved
0.05),
while
stress
remained
high
(64.5%).
Compared
consistently
inactive
students,
those
becoming
physically
active
OR
=
0.40,
0.34,
0.56)
persistently
0.43,
0.38,
0.47)
had
symptoms.
However,
adjusting
for
confounders,
activity
health
insignificant
>
Improved
0.42,
0.24,
0.42)
good
0.20,
0.37)
demonstrated
a
protective
effect
fully
demographics
socioeconomic
status.
found
that
persisted.
Although
period,
its
change
not
significantly
associated
adjustments.
reductions
depression
levels,
stress.
These
findings
highlight
importance
post-pandemic
need
targeted
interventions.
Sleep research.,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 2, 2025
Abstract
Purpose
The
purpose
of
this
systematic
review
was
to
investigate
how
smartphone
use
affected
sleep
quality.
aimed
clarify
the
nature
relationship
and
its
implications
for
overall
well‐being
health.
Methodology
Following
Preferred
Reporting
Items
Systematic
Reviews
Meta‐Analyses
(PRISMA)
2009
guidelines,
literature
published
between
2014
2024
reviewed
across
multiple
databases,
including
PubMed,
ScienceDirect,
Google
Scholar.
Studies
were
selected
based
on
their
focus
effects
quality
studies
assessed
using
modified
Newcastle–Ottawa
Scale.
Findings
After
screening
1760
records,
25
met
PRISMA
guidelines
included
in
review.
consistently
indicated
a
significant
negative
excessive
with
younger
populations
females
being
more
susceptible.
Standardized
tools
such
as
Pittsburgh
Sleep
Quality
Index
reinforced
these
findings.
However,
limitations
include
reliance
self‐reported
data
predominance
cross‐sectional
studies,
which
hinder
establishing
causality.
Conclusion
Policy
Implications
Smartphone
harms
Interventions
should
raise
awareness
blue‐light
filters,
digital
detox,
evening
device
limits.
Educational
campaigns
parents,
educators,
healthcare
providers
can
promote
healthier
habits,
especially
adolescents
young
adults.
