Frontiers in Physiology, Journal Year: 2025, Volume and Issue: 16
Published: April 1, 2025
Mild cognitive impairment (MCI) is an intermediate stage between normal aging and dementia. Emerging evidence has demonstrated that mind-body interventions may enhance function. To elucidate whether stand-alone Tai Chi Chuan (TCC) intervention confers domain-specific benefits on executive function, memory, global cognition, further investigations should be conducted. This systematic review meta-analysis of randomized controlled trials (RCTs) examined TCC's effects its duration-response relationship in adults 60 years or older with MCI. Seven electronic databases were searched for relevant literature, English as the sole inclusion criterion language. The methodological quality risk bias all included RCTs assessed using Cochrane Risk Bias (2.0) tool. pooled effect sizes evaluated standardized mean differences (SMD) 95% confidence intervals (CI). A p-value <0.05 was considered statistically significant. Nine 1,442 publications met criteria, comprising involving 1,066 participants (68.95% female) a age 74.1 (±7.4) years. Long-term TCC significant cognition (p < 0.001; SMD = 0.488; CI: 0.222-0.754), whereas short-term did not 0.172; 0.682; -0.397-1.660). Overall, showed 0.003; 0.526; 0.184-0.869). memory no improvement 0.214; 0.162; -0.094-0.417), while improved significantly 0.021; 1.010; 0.155-1.865). overall 0.005; 0.580; 0.178-0.982). Both long-term improvements function 0.006; -0.791; -1.353 to -0.230). study confirmed duration-dependent (≥60 years) Memory exhibited nonlinear temporal dynamics, characterized by acceleration plateau, invariance comparable efficacy across durations. https://www.crd.york.ac.uk/PROSPERO/home, identifier CRD42024587754.
Language: Английский