Dyslipidaemia among children and adolescents in Pakistan: a five-year retrospective cohort study based on laboratory data DOI Creative Commons

Quratul Ain,

Amjad Nawaz, Madeeha Khan

et al.

Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)

Published: March 22, 2025

Dyslipidaemia is a significant risk factor for cardiovascular diseases, which can manifest early in life. Despite its importance, the prevalence of dyslipidaemia paediatric population Pakistan remains poorly understood. This study uses laboratory data to determine and lipid testing practices among Pakistani children adolescents. retrospective cohort analysed from adolescents, aged up 19 years, who underwent testing. The was obtained two centres with collection points all over five years (March 2019–March 2024). Logistic regression models were used assess relationships between demographic factors (age, sex regions/provinces) profile parameters. Over 9,787 adolescents mean age 13.8 ± 5.1 Boys accounted 59.7% those tested compared 40.3% girls (p = 0.09). Most tests conducted Punjab (81.2%), minimal representation Balochistan (0.5%) Gilgit Baltistan (0.3%). Among 33.3% had elevated total cholesterol, 25.4% high low-density lipoprotein 46.6% low high-density 48.0% abnormal non- cholesterol 41.7% hypertriglyceridemia. Compared boys, significantly lower odds (Odds Ratio 0.556, 95% CI 0.511–0.607, p < 0.001) triglyceride levels 0.702, 0.642–0.767, 0.001). highlights children, boys more affected than girls. also gender-based inequality where appear be less frequently boys.

Language: Английский

Dyslipidaemia among children and adolescents in Pakistan: a five-year retrospective cohort study based on laboratory data DOI Creative Commons

Quratul Ain,

Amjad Nawaz, Madeeha Khan

et al.

Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)

Published: March 22, 2025

Dyslipidaemia is a significant risk factor for cardiovascular diseases, which can manifest early in life. Despite its importance, the prevalence of dyslipidaemia paediatric population Pakistan remains poorly understood. This study uses laboratory data to determine and lipid testing practices among Pakistani children adolescents. retrospective cohort analysed from adolescents, aged up 19 years, who underwent testing. The was obtained two centres with collection points all over five years (March 2019–March 2024). Logistic regression models were used assess relationships between demographic factors (age, sex regions/provinces) profile parameters. Over 9,787 adolescents mean age 13.8 ± 5.1 Boys accounted 59.7% those tested compared 40.3% girls (p = 0.09). Most tests conducted Punjab (81.2%), minimal representation Balochistan (0.5%) Gilgit Baltistan (0.3%). Among 33.3% had elevated total cholesterol, 25.4% high low-density lipoprotein 46.6% low high-density 48.0% abnormal non- cholesterol 41.7% hypertriglyceridemia. Compared boys, significantly lower odds (Odds Ratio 0.556, 95% CI 0.511–0.607, p < 0.001) triglyceride levels 0.702, 0.642–0.767, 0.001). highlights children, boys more affected than girls. also gender-based inequality where appear be less frequently boys.

Language: Английский

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