Sternum-sparing multivessel coronary surgery as a routine procedure: Midterm results of total coronary revascularization via left anterior thoracotomy DOI Creative Commons
Christian Sellin,

Ahmed Belmenai,

Margit Niethammer

et al.

JTCVS Techniques, Journal Year: 2024, Volume and Issue: 26, P. 52 - 60

Published: June 4, 2024

A sternum-sparing approach of minimally invasive total coronary revascularization via left anterior thoracotomy demonstrated promising early outcomes in unselected patients with artery multivessel disease. Follow-up data are still missing.

Language: Английский

EACTS/STS Guidelines for diagnosing and treating acute and chronic syndromes of the aortic organ DOI Open Access
Martin Czerny, Martin Grabenwöger, Tim Berger

et al.

European Journal of Cardio-Thoracic Surgery, Journal Year: 2023, Volume and Issue: 65(2)

Published: Dec. 20, 2023

A clinical guideline aims to apply all patients with a specific condition.However, there will inevitably be situations where its recommendations aren't suitable for particular patient.While healthcare professionals and others are encouraged consider these guidelines in their professional judgement, they don't override the responsibility of make decisions tailored each patient's unique circumstances.Such should aligned latest official recommendations, from relevant public health authorities, applicable rules regulations.It is important that made collaboration with, agreed upon by, patient and/or guardian or carer.

Language: Английский

Citations

111
EACTS/STS Guidelines for Diagnosing and Treating Acute and Chronic Syndromes of the Aortic Organ DOI
Martin Czerny, Martin Grabenwöger, Tim Berger

et al.

The Annals of Thoracic Surgery, Journal Year: 2024, Volume and Issue: 118(1), P. 5 - 115

Published: Feb. 26, 2024

Language: Английский

Citations

63
Twenty percent human albumin solution fluid bolus administration therapy in patients after cardiac surgery-II: a multicentre randomised controlled trial DOI Creative Commons
Geoffrey Wigmore, Adam M. Deane, Jeffrey Presneill

et al.

Intensive Care Medicine, Journal Year: 2024, Volume and Issue: 50(7), P. 1075 - 1085

Published: July 1, 2024

After cardiac surgery, fluid bolus therapy (FBT) with 20% human albumin may facilitate less and vasopressor administration than FBT crystalloids. We aimed to determine whether, after reduces the duration of compared crystalloid FBT. conducted a multicentre, parallel-group, open-label, randomised clinical trial in six intensive care units (ICUs) involving surgery patients deemed require 240 receive up 400 mL albumin/day as FBT, followed by 4% for any subsequent on that day, or at least first 1000 mL, use thereafter. The primary outcome was cumulative therapy. Secondary outcomes included balance. Of 480 patients, 466 provided consent contributed (mean age 65 years; median EuroSCORE II 1.4). 7 (interquartile range [IQR] 0–19.6) hours 10.8 (IQR 0–22.8) crystalloids (difference − 3.8 h, 95% confidence interval [CI] 8 0.4; P = 0.08). Day one balance difference 701 CI 872 530). In when crystalloid-based associated reduced positive but did not significantly reduce

Language: Английский

Citations

12
The Society of Thoracic Surgeons Adult Cardiac Surgery Database: 2023 Update on Procedure Data and Research DOI

Moritz C. Wyler von Ballmoos,

Tsuyoshi Kaneko, Alexander Iribarne

et al.

The Annals of Thoracic Surgery, Journal Year: 2023, Volume and Issue: 117(2), P. 260 - 270

Published: Nov. 29, 2023

Language: Английский

Citations

22
Effect of remimazolam versus propofol on hypotension after anesthetic induction in patients undergoing coronary artery bypass grafting: A randomized controlled trial DOI
Jae‐Woo Ju, Dong Ju Lee,

Jaeyeon Chung

et al.

Journal of Clinical Anesthesia, Journal Year: 2024, Volume and Issue: 98, P. 111580 - 111580

Published: Aug. 9, 2024

Language: Английский

Citations

7
Randomized Comparison of the Outcome of Single Versus Multiple Arterial Grafts trial (ROMA):Women—a trial dedicated to women to improve coronary bypass outcomes DOI Creative Commons
Mario Gaudino, C. Noel Bairey Merz, Sigrid Sandner

et al.

Journal of Thoracic and Cardiovascular Surgery, Journal Year: 2023, Volume and Issue: 167(4), P. 1316 - 1321

Published: June 15, 2023

Language: Английский

Citations

11
Effects of RBT-1 on preconditioning response biomarkers in patients undergoing coronary artery bypass graft or heart valve surgery: a multicentre, double-blind, randomised, placebo-controlled phase 2 trial DOI Creative Commons
André Lamy, Glenn M. Chertow, Michael E. Jessen

et al.

EClinicalMedicine, Journal Year: 2024, Volume and Issue: 68, P. 102364 - 102364

Published: Jan. 8, 2024

BackgroundRBT-1 is a combination drug of stannic protoporfin (SnPP) and iron sucrose (FeS) that elicits preconditioning response through activation antioxidant, anti-inflammatory, iron-scavenging pathways, as measured by heme oxygenase-1 (HO-1), interleukin-10 (IL-10), ferritin, respectively. Our primary aim was to determine whether RBT-1 administered before surgery would safely effectively elicit in patients undergoing cardiac surgery.MethodsThis phase 2, double-blind, randomised, placebo-controlled, parallel-group, adaptive trial, conducted 19 centres across the USA, Canada, Australia, enrolled scheduled undergo non-emergent coronary artery bypass graft (CABG) and/or heart valve with cardiopulmonary bypass. Patients were randomised (1:1:1) receive either single intravenous infusion high-dose (90 mg SnPP/240 FeS), low-dose (45 or placebo within 24–48 h surgery. The outcome preoperative response, composite plasma HO-1, IL-10, ferritin. Safety assessed adverse events laboratory parameters. Prespecified criteria permitted early stopping enrichment. This trial registered ClinicalTrials.gov, NCT04564833.FindingsBetween Aug 4, 2021, Nov 9, 2022, 135 who randomly allocated study group (46 high-dose, 45 low-dose, 44 placebo), 132 (98%) included analysis 42 placebo). At interim, proceeded full enrollment without led greater than did at (geometric least squares mean [GLSM] ratio, 3.58; 95% CI, 2.91–4.41; p < 0.0001) (GLSM 2.62; 2.11–3.24; 0.0001). generally well tolerated patients. drug-related event dose-dependent photosensitivity, observed 12 (26%) 46 treated six (13%) (safety population).InterpretationRBT-1 demonstrated statistically significant cytoprotective manageable safety profile. Further research needed. A 3 planned.FundingRenibus Therapeutics, Inc.

Language: Английский

Citations

4
Safety of Early Discharge After Coronary Artery Bypass Grafting: A Nationwide Readmissions Analysis DOI
Paige E. Brlecic, Katie Hogan, John A. Treffalls

et al.

The Annals of Thoracic Surgery, Journal Year: 2024, Volume and Issue: 118(3), P. 701 - 710

Published: June 29, 2024

Language: Английский

Citations

4
Calcific Aortic Stenosis DOI
Catherine M Otto, David E. Newby, Graham S. Hillis

et al.

JAMA, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 11, 2024

Calcific aortic stenosis (AS) restricts the valve opening during systole due to calcification and fibrosis of either a congenital bicuspid or normal trileaflet valve. In US, AS affects 1% 2% adults older than 65 years approximately 12% 75 years. Worldwide, leads more 100 000 deaths annually.

Language: Английский

Citations

4
Entrapment of Pulmonary Artery Catheters in Cardiac Surgery: A Structured Literature Review and Analysis of Published Case Reports DOI
Nicolas Kumar,

Chihiro Toda,

Étienne J. Couture

et al.

Journal of Cardiothoracic and Vascular Anesthesia, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

0