
bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 17, 2024
Abstract Objective Environmental factors have long been shown to influence brain structure and adolescent psychopathology. However, almost no research has included environmental spanning micro-to-macro-systems, structure, psychopathology in an integrated framework. Here, we assessed the ways degree which multi-system during late childhood predict subcortical volume early adolescence. Method We used baseline 2-year follow-up data from Adolescent Brain Cognitive Development SM Study ( N = 2,766). A Bayesian latent profile analysis was applied obtain distinct profiles childhood. The were a path their direct indirect effects on Results revealed nine profiles. Two predicted greater externalizing problems adolescents: (i) adversity across, family, school, neighborhood systems (ii) family conflict low school involvement. In contrast, of affluence fewer difficulties. Further, higher volume, turn, problems; whereas, economic lower Conclusion captured influences across multiple Specifying equifinal pathways serves provide evidence base for establishing different types interventions based needs risk youth. Diversity Inclusion Statement current study is part ongoing (ABCD Study®) youth are recruited elementary schools United States that informed by gender, race, ethnicity, socioeconomic status, urbanicity. ABCD Study® aims recruit longitudinally sampling sociodemographic makeup US population. authors self-identifies as member one or more historically underrepresented racial and/or ethnic groups science. One identifies gender group also representative communities collected contributed design, analysis, interpretation work. Finally, every effort made cite work minoritized academic research.
Language: Английский