Brain circuits that regulate social behavior DOI Creative Commons
Hao Li, Zhe Zhao,

Shaofei Jiang

et al.

Molecular Psychiatry, Journal Year: 2025, Volume and Issue: unknown

Published: April 26, 2025

Social interactions are essential for the survival of individuals and reproduction populations. stressors, such as social defeat isolation, can lead to emotional disorders cognitive impairments. Furthermore, dysfunctional behaviors hallmark symptoms various neuropsychiatric disorders, including autism spectrum disorder (ASD) post-traumatic stress (PTSD). Consequently, understanding neural circuit mechanisms underlying has become a major focus in neuroscience. behaviors, which encompass wide range expressions phases, regulated by complex networks. In this review, we summarize recent progress identifying circuits involved different types general investigation, preference, mating, aggression, parenting, prosocial dominance behaviors. We also outline associated with deficits ASD, schizophrenia, PTSD. Given pivotal role rodents behavior research, our review primarily focuses on these animals. Finally, propose future research directions, development specific behavioral paradigms, identification motor output, integration activity, transcriptome, connectome data, multifunctional roles neurons multiple targets, among brain regions.

Language: Английский

Brain circuits that regulate social behavior DOI Creative Commons
Hao Li, Zhe Zhao,

Shaofei Jiang

et al.

Molecular Psychiatry, Journal Year: 2025, Volume and Issue: unknown

Published: April 26, 2025

Social interactions are essential for the survival of individuals and reproduction populations. stressors, such as social defeat isolation, can lead to emotional disorders cognitive impairments. Furthermore, dysfunctional behaviors hallmark symptoms various neuropsychiatric disorders, including autism spectrum disorder (ASD) post-traumatic stress (PTSD). Consequently, understanding neural circuit mechanisms underlying has become a major focus in neuroscience. behaviors, which encompass wide range expressions phases, regulated by complex networks. In this review, we summarize recent progress identifying circuits involved different types general investigation, preference, mating, aggression, parenting, prosocial dominance behaviors. We also outline associated with deficits ASD, schizophrenia, PTSD. Given pivotal role rodents behavior research, our review primarily focuses on these animals. Finally, propose future research directions, development specific behavioral paradigms, identification motor output, integration activity, transcriptome, connectome data, multifunctional roles neurons multiple targets, among brain regions.

Language: Английский

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