The moderating effects of physical activity on social anxiety and sleep disturbance: managing gaming disorder in young e-sports players

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: Feb. 6, 2025

Internet Gaming Disorder (IGD) has emerged as an increasing public health concern, particularly among adolescent and young e-sports players in recent years. The immersive competitive nature of online gaming been associated with increase mental issues such anxiety insomnia individuals IGD. This study aims to examine the potential relationship between IGD, social anxiety, insomnia, investigate mediating role this relationship, explore moderating physical activity alleviating negative effects involved 475 aged 14-24, who typically engage average 6 h per day. Participants completed Scale-Short Form, Social Anxiety Inventory, Insomnia Severity Index, Physical Activity Frequency Question. Correlation moderation analyses were used proposed relationships. findings revealed significant positive associations insomnia. Moreover, demonstrated a correlation both Notably, served moderator IGD higher levels attenuating adverse illuminates intricate players. suggest that promoting may alleviate psychological implications These results provide important insights for formulation targeted intervention strategies aimed at demographic.

Language: Английский

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Eight weeks of resistance exercise improves mood state and intestinal permeability in healthy adults: A randomized controlled trial

Physiological Reports, Journal Year: 2025, Volume and Issue: 13(3)

Published: Feb. 1, 2025

To explore a potential link between resistance exercise and the gut-brain axis, this study examined impact of on intestinal permeability, as indicated by lipopolysaccharide binding protein (LBP), mood state in healthy adults. Sedentary participants (n = 20; 39.5 ± 12.1 y; 27.4 5.3 kg/m2) were randomly assigned to (REX) or wait-listed control (CON) groups. REX strength trained 3× weekly (advancing from 45%-55% 70%-80% 1RM for 3-4 sets over 8 weeks). Strength testing, evaluation states, collection fasting blood occurred at baseline weeks 4 8. At baseline, LBP concentrations inversely correlated all measures (r range: -0.48 -0.57; p < 0.05). The gain total [(split squat left + right)/2 bench press] was 45% higher versus CON (p 0.019), serum fell 16% rose 9% 0.014). Mood significantly improved training (but improvement not related changes LBP; r -0.001). These findings support role improving barrier function, but more research is warranted further effects axis.

Language: Английский

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Untargeted Metabolomics and Proteomics-Based Research of the Long-Term Exercise on Human Body

Applied Biochemistry and Biotechnology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 12, 2025

Language: Английский

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Menopause and mental health

Current Opinion in Obstetrics & Gynecology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 19, 2025

Purpose of review This discusses mental health changes commonly experienced by individuals during the menopause transition (MT). The pathophysiology MT, chronology and type symptoms arising from this pathophysiology, evidence-based options for treating midlife patients are discussed. concludes with treatment to enable clinicians more effectively counsel, recognize treat MT. Recent findings MT begins earlier than previously understood mood cognitive issues as common initial significantly impacting quality life. These due profound in brain’s structure, connectivity, energy metabolism, inflammation linked perimenopausal hormone shifts. Hormone therapy, psychiatric medication, psychotherapy, lifestyle adjustments all play a role management Lack both obstetrician gynecologist clinician awareness can leave undertreated vulnerable nonevidence-based approaches. Summary Patients at increased risk issues, preexisting new onset. OB/GYN plays key recognizing addressing these conditions improve outcomes women.

Language: Английский

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Neuropsychiatric Abnormalities in Metabolic Disturbances: Interplay of Adipokines and Neurotransmission

Molecular Neurobiology, Journal Year: 2025, Volume and Issue: unknown

Published: March 5, 2025

Language: Английский

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Effects of Walking and Barre Exercise on CES-D, Stress Hormones, hs-CRP, and Immunoglobulins in Elderly Women

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(5), P. 1777 - 1777

Published: March 6, 2025

Objectives: This study explored the impact of a 12-week walking and barre exercise program on depression levels (CES-D), stress hormones (dopamine, epinephrine, norepinephrine, cortisol, serotonin), high-sensitivity C-reactive protein (hs-CRP), immunoglobulins (IgA, IgG, IgM) in women aged 65 above. Methods: Twenty-seven participants were divided into group (WG), (BG) control (CG), each comprising nine individuals. Sessions lasted 50 min, thrice weekly, with intensity progressing every 4 weeks. Two-way repeated measures ANOVA assessed time-group interactions main effects, paired t-tests one-way used post hoc significance set at 0.05. Results: The CES-D scores demonstrated significant interaction (p < 0.001), decreasing significantly BG WG 0.01) while rising CG 0.05). Post analysis revealed lower compared to 0.01). Stress epinephrine cortisol showed effect time 0.05), increasing 0.05) An emerged hs-CRP IgA IgM displayed effects 0.05 p 0.01, respectively), both Conclusions: In summary, regular positively impacted depression, hormones, immune functions older women.

Language: Английский

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Curvilinear association between cardiometabolic index and depressive symptoms in individuals aged 45 and older: a cross-sectional study of CHARLS

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: March 19, 2025

This research is aimed at investigating the association between cardiometabolic index (CMI) and depressive symptoms in Chinese population of middle older age, using data derived from CHARLS study. Using 7,800 participants 2011-2012 wave cohort, this cross-sectional analysis concentrated on examining CMI symptoms, assessed through CESD-10 scores. The study utilized multivariate logistic regression, multiple linear restricted cubic spline (RCS) models to investigate link depression, with subgroup analyses offering further insights. Sensitivity included propensity score matching 8,457 2015-2016 wave. In fully adjusted models, higher was significantly associated an elevated risk having a ≥ 0.594 showing 162% compared those lower CMI. RCS identified threshold = 0.594, where had possibility depression comparison < [OR 2.62, 95% CI: 2.36-2.91]. analyses, including wave, confirmed robustness findings. Our demonstrates that levels are independently correlated heightened likelihood experiencing highlighting significance metabolic interventions mitigating tendencies middle-aged individuals.

Language: Английский

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Rethinking Depression—Beyond Neurotransmitters: An Integrated Psychoneuroendocrineimmunology Framework for Depression’s Pathophysiology and Tailored Treatment

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(6), P. 2759 - 2759

Published: March 19, 2025

It is known that the effectiveness of drug treatment for depression, ammine deficit based, largely unsatisfactory. In this review, we examine proposal a precision therapy has emerged and received strong push by identification role inflammation in depression. However, psychiatry risks being caught reductionist trap searching molecular switch resets whole system switches off disease. This an illusion since human complex depression systemic variable disorder. study, show inadequacy paradigm, and, at same time, illustrate superiority paradigm centered on psychoneuroendocrineimmunology (PNEI). According to PNEI disease being, caused different sources working together: psychological, biological, behavioral. means knowing biological psychological history subject, identifying relational crisis factors, building personalized treatments targeting those factors with tools medicine psychology, which are not reducible combination drugs psychotherapy. Our presents shift both theoretical practical, enables clinicians assess patients experiencing unified way treat them integrated manner.

Language: Английский

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A comprehensive review on the impact of polyphenol supplementation and exercise on depression and brain function parameters

Behavioral and Brain Functions, Journal Year: 2025, Volume and Issue: 21(1)

Published: March 26, 2025

The objective of this review study is to examine the combined antidepressant effects exercise and polyphenol supplementation, with a focus on specific polyphenolic compounds such as crocin, curcumin, quercetin, well different forms physical exercise, including aerobic resistance training. research examines how these interventions influence depressive-like behaviors, cognitive function, neurochemical markers in animal models human participants. findings demonstrate that both polyphenols independently contribute mood enhancement, reduced anxiety, improved function through mechanisms neurogenesis, neurotransmitter modulation, anti-inflammatory effects. Notably, showed synergistic effect, providing more significant benefits reducing symptoms depression enhancing performance, supporting overall mental well-being. These results suggest integrating supplementation could be promising non-pharmacological approach managing related disorders.

Language: Английский

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Examining the relationships of happiness and emotional symptoms, regular exercise and demographic characteristics among adolescents seeking psychological services: cross-sectional study with mediation analysis

BJPsych Open, Journal Year: 2025, Volume and Issue: 11(2)

Published: March 1, 2025

Background Adolescence marks a critical transition period, with significant mental health challenges including anxiety and depression symptoms that affect long-term happiness. There has been lack of research exploring the factors mediating adolescent Aims To investigate effects on happiness, as well contributions sociodemographic factors. Methods We recruited 392 adolescents. Anxiety symptoms, happiness were assessed by seven-item Generalized Disorder scale, nine-item Patient Health Questionnaire single-item respectively. Self-administered questionnaires used to collect information. Results Spearman correlation analysis showed negative correlations ( r = −0.37, P < 0.0001) −0.47, 0.0001). Positive predictors included quality parents’ marriage β 0.12, 0.006), regular physical exercise 0.13, 0.006) diet 0.10, 0.03). Mediation indicated depressive (estimate 0.50, 95% CI: 0.25 0.80) 0.32, 0.12 0.57) partially mediated relationship between whereas completely −0.14, −0.20 −0.08). Conclusion The findings this study highlight intricate interplay issues, lifestyle emphasise need for comprehensive interventions focusing enhancing activity addressing psychological foster among

Language: Английский

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