Magnetic molecularly imprinted polymers integrated ionic liquids for targeted detecting diamide insecticides in environmental water by HPLC-UV following MSPE

Talanta, Journal Year: 2024, Volume and Issue: 270, P. 125620 - 125620

Published: Jan. 1, 2024

Language: Английский

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Cyantraniliprole-induced intergenerational sublethal effects on fall armyworm, Spodoptera frugiperda

Crop Protection, Journal Year: 2025, Volume and Issue: unknown, P. 107116 - 107116

Published: Jan. 1, 2025

Language: Английский

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Preparation and Comprehensive Evaluation of the Efficacy and Safety of Chlorantraniliprole Nanosuspension

Toxics, Journal Year: 2024, Volume and Issue: 12(1), P. 78 - 78

Published: Jan. 16, 2024

Chlorantraniliprole is a broad-spectrum insecticide that has been widely used to control pests in rice fields. Limited by its low solubility both water and organic solvents, the development of highly efficient environmentally friendly chlorantraniliprole formulations remains challenging. In this study, low-cost scalable wet media milling technique was successfully employed prepare nanosuspension. The average particle size extremely stable nanosuspension 56 nm. Compared commercial suspension concentrate (SC), exhibited superior dispersibility, as well foliar wetting retention performances, which further enhanced bioavailability against

Language: Английский

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Low concentrations of cyantraniliprole negatively affects the development of Spodoptera frugiperda by disruption of ecdysteroid biosynthesis and carbohydrate and lipid metabolism

Pesticide Biochemistry and Physiology, Journal Year: 2024, Volume and Issue: 200, P. 105827 - 105827

Published: Feb. 12, 2024

Language: Английский

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Computational new approach methods guide focused testing and enhance understanding of chlorantraniliprole toxicity across species

Environmental Toxicology and Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 6, 2025

Diamide insecticides, specifically chlorantraniliprole (CHL), have been rising in popularity over the past decade, becoming one of most widely used insecticide classes globally. These insecticides target ryanodine receptor (RyR), primarily for control lepidopteran agricultural pests. Field studies revealed that some species developed mutations where a methionine particular position (e.g., I4790M) increases resistance to CHL. The toxicity data CHL across is limited, as case many chemicals, which creates an opportunity apply both traditional test methods and new approach (NAMs) address gaps. Here, U.S. Environmental Protection Agency's Sequence Alignment Predict Across Species Susceptibility (SeqAPASS) tool was query RyR generate susceptibility predictions exposed fill those SeqAPASS results generated testable hypotheses were guide focused acute aquatic using Daphnia magna, pulex, Pimephales promelas, Danio rerio. fish not sensitive CHL, whereas D. magna pulex found be at environmentally relevant concentrations, despite having residue I4790M mutation. Additional showed other species, including beneficial pollinators Lepidoptera, are predicted likely susceptible This study provided multiple lines evidence toward unlikelihood mutation primary cause filled knowledge gaps concerning nontarget generally amenable testing. work presents example demonstrates how NAMs can combination with types direct targeted testing build confidence predictive approaches their use risk assessment.

Language: Английский

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Neonicotinoid and bisamide insecticides in wild freshwater fish from the Wanquan River, Hainan, China: Factors affecting tissue distribution and a risk assessment

Environmental Pollution, Journal Year: 2025, Volume and Issue: unknown, P. 126053 - 126053

Published: March 1, 2025

Language: Английский

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In Silico and In Vitro Assessment Based Optimization of Potential Insecticidal Combination Against Fall Armyworm

Indian Journal of Entomology, Journal Year: 2025, Volume and Issue: unknown

Published: April 3, 2025

The fall armyworm Spodoptera frugiperda (J E Smith) is an invasive pest, causing severe economic damage to maize. present study demonstrates mining of potential insecticidal molecules using in silico analysis and validating through vitro pot experiments. Emamectin benzoate chlorantraniliprole performed best block acetylcholine esterase with respective binding energies -37.6 -35.7 KJ/ mol multiple hydrogen hydrophobic interactions. showed the strongest (ΔG -41 mol) followed by -34.3 inhibit ryanodine receptors, whereas, -27.2 emamectin benzoate(ΔG -26.3 GABA. In activity revealed strong action chlorantraniliprole(LC500.039 ppm) (LC50 0.027 ppm), however their combined effect maintaining0.75-1:0.9-2.5 (%, w/w) was highly promising LC50 0.01 ppm. SBOD-23 formulation consisting both insecticides at a concentration 20 times (ppm) least whorl maize highest plant weight without any phytotoxicity.

Language: Английский

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Characterization of cyantraniliprole resistance in Spodoptera frugiperda: Selection, inheritance pattern, and cross‐resistance to other diamide insecticides

Pest Management Science, Journal Year: 2025, Volume and Issue: unknown

Published: April 17, 2025

Abstract BACKGROUND Cyantraniliprole, a diamide insecticide, is widely used in Brazil to control sucking and defoliating pests, including the fall armyworm ( Spodoptera frugiperda ), major agricultural pest. However, increasing resistance diamides has raised concerns about long‐term effectiveness of cyantraniliprole. This study aimed (i) assess evolution cyantraniliprole field populations S. , (ii) investigate cross‐resistance other diamides, (iii) analyze role I4790K mutation mechanisms. RESULTS A significant decrease susceptibility was observed Brazil, particularly regions with intensive systems, such as Brazilian Cerrado, from 2017 2023. cyantraniliprole‐resistant strain selected field‐collected population Bahia (BA) using F 2 screening method. The inheritance this autosomal recessive monogenic, 3414‐fold ratio. High flubendiamide, chlorantraniliprole, cyclaniliprole also detected. Molecular analysis confirmed presence homozygous ryanodine receptor gene one mechanisms strain. CONCLUSION These findings highlight decreased accelerating insecticides due cross‐resistance. results underscore urgent need for integrated pest management (IPM) strategies, insecticide rotation monitoring, preserve efficacy insecticides. © 2025 Author(s). Pest Management Science published by John Wiley & Sons Ltd on behalf Society Chemical Industry.

Language: Английский

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Design, sonic solvothermal synthesis, synergistically improved bioactivity and photo-self-degradability of sulfonyl phenylpyrazole two-site alkaloids fused amides and amine units as GABA receptor inhibitors

Industrial Crops and Products, Journal Year: 2024, Volume and Issue: 222, P. 119507 - 119507

Published: Aug. 29, 2024

Language: Английский

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Genome-wide analysis of detoxification genes conferring diamide insecticide resistance in Spodoptera exigua identifies CYP9A40

Chemosphere, Journal Year: 2024, Volume and Issue: 367, P. 143623 - 143623

Published: Nov. 1, 2024

For over a decade, diamide insecticides have been effective against lepidopteran pests like beet armyworm, Spodoptera exigua (Hübner, 1808). However, the evolution of resistance poses challenge to their sustainable use. We identified an I4790 M mutation in S. ryanodine receptor (RyR) gene, but its correlation with varied across field-collected Korean populations exigua. RNA sequencing and differential gene expression analysis were performed investigate other mechanisms. Diamide-resistant susceptible strains F1 hybrids compared by mapping RNA-seq reads reference genome. CYP9A40 was as critical due high resistant strains. Synergist bioassays piperonyl butoxide supported role P450s metabolic A strong positive between over-expression levels (up 80-fold) LC

Language: Английский

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