Emerging targets for advancing endometrial therapeutics DOI Creative Commons
Signe Altmäe,

Aida Rodríguez-Santisteban

Reproductive BioMedicine Online, Journal Year: 2025, Volume and Issue: 50(4), P. 104785 - 104785

Published: April 1, 2025

The endometrium plays a crucial role in female health. Globally, millions of women are affected by endometrial/uterine disorders, yet the and its gynaecological pathologies have been understudied. Gaining insight into detailed endometrial architecture, gene expression, spatial temporal cellular interactions, microenvironment is essential for understanding physiology pathophysiology this dynamic tissue. current paper highlights latest targets advancing research that include single-cell RNA sequencing, transcriptomics, microbiome, organoid models, analysis menstrual blood less-studied ageing. authors hope summary will provide more novel methods, highlight therapeutics inspire readers to generate fresh ideas future avenues.

Language: Английский

Emerging targets for advancing endometrial therapeutics DOI Creative Commons
Signe Altmäe,

Aida Rodríguez-Santisteban

Reproductive BioMedicine Online, Journal Year: 2025, Volume and Issue: 50(4), P. 104785 - 104785

Published: April 1, 2025

The endometrium plays a crucial role in female health. Globally, millions of women are affected by endometrial/uterine disorders, yet the and its gynaecological pathologies have been understudied. Gaining insight into detailed endometrial architecture, gene expression, spatial temporal cellular interactions, microenvironment is essential for understanding physiology pathophysiology this dynamic tissue. current paper highlights latest targets advancing research that include single-cell RNA sequencing, transcriptomics, microbiome, organoid models, analysis menstrual blood less-studied ageing. authors hope summary will provide more novel methods, highlight therapeutics inspire readers to generate fresh ideas future avenues.

Language: Английский

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