Green synthesis of silver nanoparticles using aerial parts of Asparagus racemosus Willd: characterization, antioxidant, antidiabetic, cytotoxicity, and antibacterial activities DOI Creative Commons

Priya Das,

Subhajit Mondal,

Gouhar Jahan Ashraf

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 19, 2024

Abstract Asparagus racemosus Willd is a well-known medicinal plant due to its various therapeutic aspects. The aerial part of A. was utilized formulate cost-effective and environmentally friendly silver nanoparticles through green approach. surface plasmon resonance band racemosus-mediated (AgNPs-AR) established at the λmax 426 nm in UV-visible analysis, confirming formation AgNPs-AR this synthesis method. diameter spherical-shaped 202 nm. characterization done by using Fourier Transform Infrared (FT-IR) spectroscopy, Transmission Electron Microscopy (TEM), Scanning (SEM), Energy-Dispersive X-ray (EDX), Powder Diffraction (XRD), Dynamic Light Scattering (DLS), Zeta potential analyses. Additionally, therapeutical potentialities were assessing antioxidant, antidiabetic, anticancer, antibacterial properties. DPPH free radical assay showed potent scavenging ability (IC50: 639 µg/ml). Increasing absorbance with increasing concentration confirmed reducing power AgNPs-AR. α-amylase inhibitory demonstrated significant inhibition 535 µg/ml), indicating antidiabetic They also exhibited notable cytotoxicity 57.65 µg/ml) against malignant human kidney cells excellent activity both Staphylococcus aureus (Gram-positive) Escherichia coli (Gram-negative) bacteria. Thus, study concluded that promising cytotoxic, activities, which can deliver new candidate for drug discovery research.

Language: Английский

Utilizing Cinnamomum verum extract for green synthesis of silver nanoparticles: Exploring optical properties, morphology, and potential applications DOI Creative Commons
Meznah M. Alanazi

Journal of King Saud University - Science, Journal Year: 2024, Volume and Issue: 36(8), P. 103312 - 103312

Published: June 17, 2024

One of the most widely used medicinal herbs, cinnamon verum, has numerous pharmacological applications in traditional medicine. In this work, an aqueous extract Cinnamomum verum (Cv) was to produce silver nanoparticles (AgNPs). Numerous methods were study Cv-AgNPs, including transmission electron microscopy(TEM), dynamic light scattering(DLS), ultraviolet–visible spectrophotometry(UV–vis), energy-dispersive spectroscopy (EDS), X-ray diffraction(XRD), and Fourier-transform infrared (FT-IR). The face-centered cubic(FCC) crystal structure with average crystallite size 19.25 nm, been revealed by XRD pattern analysis. MTT assay utilized evaluate anti-tumor cytotoxic effects Cv-AgNPs on MCF-7 HeLa cell lines. Moreover, anticancer activity demonstrated using human cervical cancer cells(HeLA) breast line(MCF-7). results showed that demonstrate vitro viability 9 % 6 for Hela line, respectively, based 500 μl consumed 24 h. This Cv-AgNPs' potency as agent. Taking everything into account, work proposes environmentally friendly way synthesize Cv-Ag NPs, which may find use bio-nanomedicine.

Language: Английский

Citations

1
Green synthesis of silver nanoparticles using aerial parts of Asparagus racemosus Willd: characterization, antioxidant, antidiabetic, cytotoxicity, and antibacterial activities DOI Creative Commons

Priya Das,

Subhajit Mondal,

Gouhar Jahan Ashraf

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 19, 2024

Abstract Asparagus racemosus Willd is a well-known medicinal plant due to its various therapeutic aspects. The aerial part of A. was utilized formulate cost-effective and environmentally friendly silver nanoparticles through green approach. surface plasmon resonance band racemosus-mediated (AgNPs-AR) established at the λmax 426 nm in UV-visible analysis, confirming formation AgNPs-AR this synthesis method. diameter spherical-shaped 202 nm. characterization done by using Fourier Transform Infrared (FT-IR) spectroscopy, Transmission Electron Microscopy (TEM), Scanning (SEM), Energy-Dispersive X-ray (EDX), Powder Diffraction (XRD), Dynamic Light Scattering (DLS), Zeta potential analyses. Additionally, therapeutical potentialities were assessing antioxidant, antidiabetic, anticancer, antibacterial properties. DPPH free radical assay showed potent scavenging ability (IC50: 639 µg/ml). Increasing absorbance with increasing concentration confirmed reducing power AgNPs-AR. α-amylase inhibitory demonstrated significant inhibition 535 µg/ml), indicating antidiabetic They also exhibited notable cytotoxicity 57.65 µg/ml) against malignant human kidney cells excellent activity both Staphylococcus aureus (Gram-positive) Escherichia coli (Gram-negative) bacteria. Thus, study concluded that promising cytotoxic, activities, which can deliver new candidate for drug discovery research.

Language: Английский

Citations

0