Green Synthesis Of Zinc And Titanium Nanoparticles Using HG Seed Extract: A Sustainable Approach To Nanotechnology DOI Creative Commons

Sujana Kariveda

African Journal of Biomedical Research, Journal Year: 2024, Volume and Issue: unknown, P. 241 - 250

Published: Dec. 31, 2024

This study explores the biosynthesis of zinc (Zn) and titanium (Ti) nanoparticles (NPs) using HG seed extract as a reducing stabilizing agent. The synthesis was initially evidenced by visible colour change, indicative metal ion reduction nanoparticle formation. UV-Vis spectroscopy confirmed presence Zn TiNPs through distinct SPR peaks at 270 nm 320 nm, respectively. SEM revealed spherical with sizes ranging from 135–225 for NPs 84.2–138 TiNPs, while TEM provided high-resolution insights, confirming their uniform morphology crystalline nature. FTIR identified bioactive compounds, including proteins phenolics, involved in stabilization, showcasing role natural capping agents. HG-mediated green process produced desirable size, morphology, stability, demonstrating its efficiency eco-friendliness. highlights potential sustainable alternative synthesis, broad applications biomedicine, environmental remediation, nanotechnology.

Language: Английский

Biofilm Resilience: Molecular Mechanisms Driving Antibiotic Resistance in Clinical Contexts DOI Creative Commons
Ahmad Almatroudi

Biology, Journal Year: 2025, Volume and Issue: 14(2), P. 165 - 165

Published: Feb. 6, 2025

Healthcare-associated infections pose a significant global health challenge, negatively impacting patient outcomes and burdening healthcare systems. A major contributing factor to healthcare-associated is the formation of biofilms, structured microbial communities encased in self-produced extracellular polymeric substance matrix. Biofilms are critical disease etiology antibiotic resistance, complicating treatment infection control efforts. Their inherent resistance mechanisms enable them withstand therapies, leading recurrent increased morbidity. This review explores development biofilms their dual roles disease. It highlights structural protective functions EPS matrix, which shields populations from immune responses antimicrobial agents. Key molecular biofilm including restricted penetration, persister cell dormancy, genetic adaptations, identified as barriers effective management. implicated various clinical contexts, chronic wounds, medical device-associated infections, oral complications, surgical site infections. prevalence hospital environments exacerbates challenges underscores urgent need for innovative preventive therapeutic strategies. evaluates cutting-edge approaches such DNase-mediated disruption, RNAIII-inhibiting peptides, DNABII proteins, bacteriophage nanoparticle-based solutions, coatings, lock therapies. also examines associated with biofilm-related diagnostic difficulties, disinfectant economic implications. emphasizes multidisciplinary approach importance understanding dynamics, role pathogenesis, advancements strategies combat biofilm-associated effectively settings. These insights aim enhance reduce burden diseases.

Language: Английский

Citations

1
Antibacterial Action of Curcumin Nanocrystals on Streptococcus Mutans DOI Creative Commons
Mohammad Yousef Memar, Mina Yekani, Yashar Rezaei

et al.

The Open Dentistry Journal, Journal Year: 2025, Volume and Issue: 19(1)

Published: March 20, 2025

Aims The present study aimed to investigate the antibacterial and antibiofilm properties adhesion inhibitory effect of curcumin nanocrystals compared bulk against Streptococcus mutans . Background S. is main aetiological factor in tooth decay. Curcumin has been used various studies as an antimicrobial agent due its wide traditional uses low side effects. Despite having multiple therapeutic effects, inherent properties, for example, poor aquas solubility, bioavailability, photodegradation, chemical instability, rapid metabolism, short half-life, limit pharmaceutical significance.Recently, newer strategies have tried overcome these pharmacological issues improve curcumin's efficacy. nanoformulation can enhance effectiveness a range diseases, especially infectious diseases. Methods evaluated Minimum Inhibitory Concentration (MIC), biofilm inhibitory, actions Results results showed that were more effective than MICs spectrum was 256-512 µg/mL 125-256 µg/mL, respectively. Both inhibited formation ( p <0.05), bacterial significantly decreased control <0.05). Conclusion These findings using mouthwashes toothpaste be useful preventing dental plaque. Further research required determine stability formulation with other product ingredients assess their safety efficacy human clinical trials.

Language: Английский

Citations

0
Green Synthesis Of Zinc And Titanium Nanoparticles Using HG Seed Extract: A Sustainable Approach To Nanotechnology DOI Creative Commons

Sujana Kariveda

African Journal of Biomedical Research, Journal Year: 2024, Volume and Issue: unknown, P. 241 - 250

Published: Dec. 31, 2024

This study explores the biosynthesis of zinc (Zn) and titanium (Ti) nanoparticles (NPs) using HG seed extract as a reducing stabilizing agent. The synthesis was initially evidenced by visible colour change, indicative metal ion reduction nanoparticle formation. UV-Vis spectroscopy confirmed presence Zn TiNPs through distinct SPR peaks at 270 nm 320 nm, respectively. SEM revealed spherical with sizes ranging from 135–225 for NPs 84.2–138 TiNPs, while TEM provided high-resolution insights, confirming their uniform morphology crystalline nature. FTIR identified bioactive compounds, including proteins phenolics, involved in stabilization, showcasing role natural capping agents. HG-mediated green process produced desirable size, morphology, stability, demonstrating its efficiency eco-friendliness. highlights potential sustainable alternative synthesis, broad applications biomedicine, environmental remediation, nanotechnology.

Language: Английский

Citations

0