The effect of adipose-derived mesenchymal stem cells against high fructose diet induced liver dysfunction and dysbiosis DOI Creative Commons
Marwa Mohammed, Nissim Hay, Mazher Mohammed

et al.

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 5, 2024

Abstract High fructose diet (HFrD) has been approved to be involved in the pathogenesis of insulin resistance. Mesenchymal stem cells have a vital role treatment various diseases including metabolic disturbances. We investigated effect Adipose-derived mesenchymal (ADMSCs) against HFrD-induced disorders and molecular mechanisms for this effect. Rats were divided into 3 groups; control, HFrD, combined HFrD with ADMSCs. assessed liver functions, gut microbiota activity, oxidative stress, adiponectin, IL10 levels. Also, we measured SREBP-1, IRS-1 expression using Western blot, Malat1 rt-PCR. ADMSCs antagonized abnormalities induced by form improvement functions alleviation stress. In addition, ameliorated activity besides elevation adiponectin attenuated resistance through upregulation IRS1 downregulation SREBP-1 Malat1. can protect hazards.

Language: Английский

Nanotechnology-based biotherapeutics for physiological wound healing phases DOI Creative Commons
Shohreh Fahimirad, Fahimeh Fattahi, Mehrnaz Hatami

et al.

Industrial Crops and Products, Journal Year: 2025, Volume and Issue: 226, P. 120608 - 120608

Published: Feb. 6, 2025

Language: Английский

Citations

1
Advances in the study of polysaccharide-based hydrogel wound dressings DOI
Yu Zhang, Ning Qiao, Lihua Liu

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142134 - 142134

Published: March 1, 2025

Language: Английский

Citations

1
Advances in the development of medical dressings for the treatment of diabetic foot wounds DOI
Ming Cai, Zhao Liu,

Xun Sun

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 498, P. 155575 - 155575

Published: Sept. 7, 2024

Language: Английский

Citations

5
Extracellular vesicles: unlocking therapeutic potential in regenerative medicine DOI
Pouria Samadi, Mohsen Sheykhhasan, Karima Mokhtari

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 397 - 435

Published: Jan. 1, 2025

Language: Английский

Citations

0
Extracellular vesicles in reproductive medicines DOI
Karima Mokhtari, Mohsen Sheykhhasan, Mina Shahnazari

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 243 - 281

Published: Jan. 1, 2025

Citations

0
Mesenchymal Stem Cell-Derived Exosomes Hold Promise in the Treatment of Diabetic Foot Ulcers DOI Creative Commons
Hui Wang,

Sensen Wu,

Xinyu Bai

et al.

International Journal of Nanomedicine, Journal Year: 2025, Volume and Issue: Volume 20, P. 5837 - 5857

Published: May 1, 2025

Language: Английский

Citations

0
Extracellular Vesicles in Cancer Immunotherapy: Therapeutic, Challenges and Clinical Progress DOI Creative Commons
Hamed Manoochehri,

Anita Silas La’ah,

Ali Babaeizad

et al.

Asian Journal of Pharmaceutical Sciences, Journal Year: 2025, Volume and Issue: unknown, P. 101065 - 101065

Published: May 1, 2025

Language: Английский

Citations

0
Optimization and Preparation of Doxycycline-Loaded Chitosan Nanoparticles Using Box-Behnken Design for Better Diabetic Wound Healing DOI
Harish Bhardwaj, Ram Kumar Sahu, Rajendra Jangde

et al.

Journal of Pharmaceutical Sciences, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

Citations

1
The effect of adipose-derived mesenchymal stem cells against high fructose diet induced liver dysfunction and dysbiosis DOI Creative Commons
Marwa Mohammed, Nissim Hay, Mazher Mohammed

et al.

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 5, 2024

Abstract High fructose diet (HFrD) has been approved to be involved in the pathogenesis of insulin resistance. Mesenchymal stem cells have a vital role treatment various diseases including metabolic disturbances. We investigated effect Adipose-derived mesenchymal (ADMSCs) against HFrD-induced disorders and molecular mechanisms for this effect. Rats were divided into 3 groups; control, HFrD, combined HFrD with ADMSCs. assessed liver functions, gut microbiota activity, oxidative stress, adiponectin, IL10 levels. Also, we measured SREBP-1, IRS-1 expression using Western blot, Malat1 rt-PCR. ADMSCs antagonized abnormalities induced by form improvement functions alleviation stress. In addition, ameliorated activity besides elevation adiponectin attenuated resistance through upregulation IRS1 downregulation SREBP-1 Malat1. can protect hazards.

Language: Английский

Citations

0