Zinc sulfate gel reshapes the wound microenvironment to promote full-thickness wound healing in mice DOI Creative Commons
Ying Zhang, Xuebo Wei, Yun Xu

et al.

Regenerative Therapy, Journal Year: 2025, Volume and Issue: 28, P. 582 - 590

Published: Feb. 14, 2025

Language: Английский

Preparation and evaluation of a novel alginate-arginine-zinc ion hydrogel film for skin wound healing DOI

Ganzhe Mao,

Shuya Tian,

Yanxia Shi

et al.

Carbohydrate Polymers, Journal Year: 2023, Volume and Issue: 311, P. 120757 - 120757

Published: March 2, 2023

Language: Английский

Citations

65
Chitosan-Based Biomaterials for Hemostatic Applications: A Review of Recent Advances DOI Open Access
Daniela Gheorghiță, Horaţiu Moldovan, Alina Robu

et al.

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(13), P. 10540 - 10540

Published: June 23, 2023

Hemorrhage is a detrimental event present in traumatic injury, surgery, and disorders of bleeding that can become life-threatening if not properly managed. Moreover, uncontrolled complicate surgical interventions, altering the outcome procedures. Therefore, to reduce risk complications decrease morbidity mortality associated with hemorrhage, it necessary use an effective hemostatic agent ensures immediate control bleeding. In recent years, there have been increasingly rapid advances developing novel generation biomaterials properties. Nowadays, wide array topical agents available, including chitosan-based shown outstanding properties such as antibacterial, antifungal, hemostatic, analgesic activity addition their biocompatibility, biodegradability, wound-healing effects. This review provides analysis discusses progress made performance, mechanism action, efficacy, cost, safety years.

Language: Английский

Citations

58
A calcium and zinc composite alginate hydrogel for pre-hospital hemostasis and wound care DOI
Abhishek Kumar, Dhananjay Kumar Sah, Kushagra Khanna

et al.

Carbohydrate Polymers, Journal Year: 2022, Volume and Issue: 299, P. 120186 - 120186

Published: Oct. 6, 2022

Language: Английский

Citations

52
Recent research advances on polysaccharide-, peptide-, and protein-based hemostatic materials: A review DOI

Hanjie Shao,

Xiang Wu, Ying Xiao

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 261, P. 129752 - 129752

Published: Jan. 26, 2024

Language: Английский

Citations

18
Nanosphere-reinforced polysaccharide self-healing hydrogels for infected wound healing DOI

Yikun Ju,

Huaqian Xue,

Yang Pu

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 264, P. 130593 - 130593

Published: March 2, 2024

Language: Английский

Citations

13
Advances of biological macromolecules hemostatic materials: A review DOI
Mengyang Zhang,

Feng Han,

Xunxin Duan

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 269, P. 131772 - 131772

Published: April 24, 2024

Language: Английский

Citations

10
Are All Alginate Dressings Equivalent? DOI Creative Commons

Laura Duciel,

Richard Proust,

Anne‐Charlotte Ponsen

et al.

Journal of Biomedical Materials Research Part B Applied Biomaterials, Journal Year: 2025, Volume and Issue: 113(3)

Published: Feb. 20, 2025

ABSTRACT Alginate dressings are widely used in wound treatment for their healing and hemostatic properties capacity to drain exudate. However, a clear understanding of the heterogeneity within this class is lacking. Numerous sources variability exist between alginate dressings: composition (% calcium relative other components), ratio D‐Mannuronic L‐Guluronic acids fraction, purity (presence toxic contaminants), shape fibers (surface thickness). These parameters affect performance safety dressings, which may thus not be interchangeable clinical practice. Therefore, clinicians must aware these differences ensure optimal avoid complications or suboptimal healing. The objective study was compare six conclude on equivalence. results obtained demonstrate considerable assessed characteristics: composition, Ca 2+ release, level cytotoxicity, fiber shape, draining capacity, resistance traction. Algostéril, only pure rich G, releases specific dose non‐cytotoxic dressing. With its multilobed that statistically thickest, it provides best greatest equivalent. Each dressing distinct, consequently one cannot transposed others. each should own efficacy, given indication, through trial.

Language: Английский

Citations

2
Alginate based biomaterials for hemostatic applications: Innovations and developments DOI
Ankita Sharma, Chetna Verma, Pratibha Singh

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 264, P. 130771 - 130771

Published: March 11, 2024

Language: Английский

Citations

9
Recent Advances in Topical Hemostatic Materials DOI
Liu Yang, Yi Zhang, Weifeng Yao

et al.

ACS Applied Bio Materials, Journal Year: 2024, Volume and Issue: 7(3), P. 1362 - 1380

Published: Feb. 19, 2024

Untimely or improper treatment of traumatic bleeding may cause secondary injuries and even death. The traditional hemostatic modes can no longer meet requirements coping with complicated emergencies. With scientific technological advancements, a variety topical materials have been investigated involving inorganic, biological, polysaccharide, carbon-based materials. These their respective merits defects. In this work, the application mechanism major materials, especially some nanomaterials excellent adhesion, good biocompatibility, low toxicity, high adsorption capacity, are summarized. future, it is prospect to develop multifunctional hemostasis antibacterial anti-inflammatory properties for promoting wound healing.

Language: Английский

Citations

8
The role and application of metal ions in maxillofacial bone defect DOI
Xinyue Hu,

Dongqi You,

T Fei

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 493, P. 152317 - 152317

Published: May 24, 2024

Language: Английский

Citations

7