Assessment of knowledge, attitude, and practice on early childhood caries among dental undergraduates and residents in China

BMC Medical Education, Journal Year: 2024, Volume and Issue: 24(1)

Published: March 4, 2024

Abstract Background Early childhood caries (ECC) causes severe, widespread oral health issues in children. Dental undergraduates and residents are expected to have a solid understanding of ECC for children’s promotion. This study aimed evaluate the knowledge, attitude, clinical practice on among dental China. Methods A 23-item electronic questionnaire was distributed 598 (4th- 5th-year undergraduates) (1st-, 2nd-, 3rd-year residents) at School Stomatology, Wuhan University, China (in April–May 2023). SPSS Statistics used analyze data using Chi-square test significance level 0.05. Results total 422 questionnaires were completed by participants (recovery rate: 70.6%) from various academic levels. Around 77.3% had heard (mainly textbooks), only 27.5% considered themselves familiar with it. Residents (79.8%) higher risk awareness overall than (58.3%) ( p < 0.05), but 54.0% correctly defined ECC. Most positive ECC’s pathogenic factors preventive measures, including feeding patterns (71.6%), fluoride application (93.4%), teeth cleaning (93.1%). Furthermore, 50.2% encountered cases clinic. Conclusions Despite having suboptimal ECC-related knowledge practice, demonstrated more attitude towards its etiology-based prevention. Strengthening education, guidance, may enable them gain better learning, which would benefit health.

Language: Английский

---

Antimicrobial, remineralization, and infiltration: advanced strategies for interrupting dental caries

Medical Review, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 22, 2024

Dental caries, driven by plaque biofilm, poses a major oral health challenge due to imbalance in mineralization and demineralization. The primary objective caries management is maintain biofilm homeostasis while facilitating the repair regeneration of dental hard tissues, thus restoring both structural integrity functionality affected teeth. Though antimicrobial remineralization approaches haven shown promise, their standalone utilization without concurrent bacterial control or rebalancing lacks an integrated strategy effectively arrest progression. Furthermore, according principles minimally invasive dentistry, treatment materials should exhibit high permeability ensure optimal sealing demineralized tooth surfaces. concept interrupting (IDC) has emerged as holistic approach, drawing upon extensive research encompassing three pivotal techniques: antibacterial strategies, therapies, infiltration mechanisms, all which are indispensable components combating progression caries. In this review, we provide comprehensive overview mechanisms applications antibacterial, remineralization, technologies within context management. Additionally, summarize advanced that align with IDC concept, aiming offer valuable insights for designing next-generation adept at preventing halting efficiently.

Language: Английский

---

Metformin reduced the alkaline resistance of Enterococcus faecalis against calcium hydroxide via Man-PTS EII: in vitro and in vivo studies

Clinical Oral Investigations, Journal Year: 2024, Volume and Issue: 28(10)

Published: Sept. 10, 2024

Language: Английский

---

Natural Bioactive Epigallocatechin-Gallate Promote Bond Strength and Differentiation of Odontoblast-like Cells

Biomimetics, Journal Year: 2023, Volume and Issue: 8(1), P. 75 - 75

Published: Feb. 10, 2023

The (-)-Epigallocatechin-gallate (EGCG) metabolite is a natural polyphenol derived from green tea and associated with antioxidant, biocompatible, anti-inflammatory effects.To evaluate the effects of EGCG to promote odontoblast-like cells differentiated human dental pulp stem (hDPSCs); antimicrobial on Escherichia coli, Streptococcus mutans, Staphylococcus aureus; improve adhesion enamel dentin by shear bond strength (SBS) adhesive remnant index (ARI).hDSPCs were isolated tissue immunologically characterized. EEGC dose-response viability was calculated MTT assay. Odontoblast-like hDPSCs tested for mineral deposition activity alizarin red, Von Kossa, collagen/vimentin staining. Antimicrobial assays performed in microdilution test. Demineralization teeth performed, conducted incorporating an system testing SBS-ARI. data analyzed normalized Shapiro-Wilks test ANOVA post hoc Tukey test.The positive CD105, CD90, vimentin negative CD34. (3.12 µg/mL) accelerated differentiation cells. mutans exhibited highest susceptibility < aureus coli. increased (p 0.05) adhesion, cohesive failure most frequent.(-)-Epigallocatechin-gallate nontoxic, promotes into cells, possesses antibacterial effect, increases adhesion.

Language: Английский

---

Unraveling Nanomaterials in Biomimetic Mineralization of Dental Hard Tissue: Focusing on Advantages, Mechanisms, and Prospects

Advanced Science, Journal Year: 2024, Volume and Issue: 11(40)

Published: Aug. 29, 2024

Abstract The demineralization of dental hard tissue imposes considerable health and economic burdens worldwide, but an optimal method that can repair both the chemical composition complex structures has not been developed. continuous development nanotechnology created new opportunities for regeneration tissue. Increasingly studies have reported nanomaterials (NMs) induce regulate biomimetic mineralization tissue, few examined how they are involved in different stages, let alone relevant mechanisms action. Besides their nanoscale dimensions excellent designability, NMs play a corresponding role function raw materials mineralization, mineralized microenvironment, guidance, products. This review comprehensively summarizes advantages examines specific mechanisms. Design strategies to promote summarized according application purpose oral cavity, limitations directions remineralization proposed. provide theoretical basis understand interaction between thereby optimizing design strategy, rational development, clinical field remineralization.

Language: Английский

---