Nanomedicine,
Journal Year:
2024,
Volume and Issue:
20(3), P. 305 - 318
Published: Dec. 30, 2024
Colorectal
cancer
(CRC)
is
a
significant
threat
to
human
health.
The
dynamic
equilibrium
between
probiotics
and
pathogenic
bacteria
within
the
gut
microbiota
crucial
in
mitigating
risk
of
CRC.
An
overgrowth
harmful
microorganisms
gastrointestinal
tract
can
result
an
excessive
accumulation
bacterial
toxins
carcinogenic
metabolites,
thereby
disrupting
delicate
balance
microbiota.
This
disruption
may
lead
alterations
microbial
composition,
impairment
mucosal
barrier
function,
potential
promotion
abnormal
cell
proliferation,
ultimately
contribute
progression
Recently,
research
has
indicated
that
intestinal
presence
Fusobacterium
nucleatum
(Fn)
significantly
influences
onset,
progression,
metastasis
Consequently,
interaction
CRC
cells
Fn
presents
promising
strategy
against
Nanomaterials
have
been
extensively
utilized
therapy
infection
control,
demonstrating
substantial
treating
bacteria-associated
tumors.
review
begins
by
elucidating
mechanisms
occurrence
CRC,
with
particular
emphasis
on
clarifying
intricate
relationship
Subsequently,
we
highlight
strategies
utilize
nanomaterials
disrupt
association
Overall,
this
offers
valuable
insight
guidance
for
leveraging
therapy.
Proceedings of Anticancer Research,
Journal Year:
2024,
Volume and Issue:
8(3), P. 68 - 73
Published: June 19, 2024
This
paper
aims
to
review
the
association
between
gut
microbiota
and
respiratory
system
diseases,
explore
their
potential
mechanisms
clinical
significance.
Gut
microbiota,
as
an
important
microbial
ecosystem
in
human
body,
has
profound
effects
on
host
health.
Recent
studies
have
shown
that
imbalance
of
is
closely
related
occurrence
development
including
asthma,
chronic
obstructive
pulmonary
disease
(COPD),
pneumonia.
We
comprehensively
analyzed
current
research
progress
found
may
affect
diseases
through
various
pathways,
immune
regulation,
inflammatory
responses,
airway
mucus
secretion.
Additionally,
environmental
factors,
lifestyle,
dietary
habits
are
also
Understanding
relationship
not
only
helps
reveal
but
provides
a
theoretical
basis
for
new
treatment
strategies.
Future
should
focus
exploring
types
functions
conducting
trials
based
this,
investigating
modulation
prevention
providing
directions
personalized
medicine.
Biomolecules,
Journal Year:
2024,
Volume and Issue:
14(12), P. 1638 - 1638
Published: Dec. 20, 2024
The
gut
microbiota,
a
complex
ecosystem,
is
vital
to
host
health
as
it
aids
digestion,
modulates
the
immune
system,
influences
metabolism,
and
interacts
with
brain-gut
axis.
Various
factors
influence
composition
of
this
microbiota.
Enzymes,
essential
catalysts,
actively
participate
in
biochemical
reactions
that
have
an
impact
on
microbial
community,
affecting
both
microorganisms
environment.
Enzymes
play
important
role
regulation
intestinal
but
interactions
between
enzymes
communities,
well
precise
mechanisms
enzymes,
remain
challenge
scientific
research.
serve
traditional
nutritional
functions,
such
breakdown
substrates
into
absorbable
small
molecules,
non-nutritional
roles,
which
encompass
antibacterial
function,
immunomodulation,
maintenance,
stress
reduction,
among
others.
This
study
categorizes
according
their
source
explores
mechanistic
principles
by
drive
activity,
including
promotion
proliferation,
direct
elimination
harmful
microbes,
modulation
bacterial
interaction
networks,
reduction
stress.
A
systematic
understanding
regulating
microbiota
associated
molecular
will
facilitate
application
precisely
regulate
future
suggest
new
therapeutic
strategies
dietary
recommendations.
In
conclusion,
review
provides
comprehensive
overview
modulating
It
underlying
cellular
discusses
potential
applications
enzyme-mediated
for
health.
Nanomedicine,
Journal Year:
2024,
Volume and Issue:
20(3), P. 305 - 318
Published: Dec. 30, 2024
Colorectal
cancer
(CRC)
is
a
significant
threat
to
human
health.
The
dynamic
equilibrium
between
probiotics
and
pathogenic
bacteria
within
the
gut
microbiota
crucial
in
mitigating
risk
of
CRC.
An
overgrowth
harmful
microorganisms
gastrointestinal
tract
can
result
an
excessive
accumulation
bacterial
toxins
carcinogenic
metabolites,
thereby
disrupting
delicate
balance
microbiota.
This
disruption
may
lead
alterations
microbial
composition,
impairment
mucosal
barrier
function,
potential
promotion
abnormal
cell
proliferation,
ultimately
contribute
progression
Recently,
research
has
indicated
that
intestinal
presence
Fusobacterium
nucleatum
(Fn)
significantly
influences
onset,
progression,
metastasis
Consequently,
interaction
CRC
cells
Fn
presents
promising
strategy
against
Nanomaterials
have
been
extensively
utilized
therapy
infection
control,
demonstrating
substantial
treating
bacteria-associated
tumors.
review
begins
by
elucidating
mechanisms
occurrence
CRC,
with
particular
emphasis
on
clarifying
intricate
relationship
Subsequently,
we
highlight
strategies
utilize
nanomaterials
disrupt
association
Overall,
this
offers
valuable
insight
guidance
for
leveraging
therapy.
