Copper metabolism in osteoarthritis and its relation to oxidative stress and ferroptosis in chondrocytes DOI Creative Commons
Qingyuan Yu, Yanan Xiao, Mengqi Guan

et al.

Frontiers in Molecular Biosciences, Journal Year: 2024, Volume and Issue: 11

Published: Sept. 11, 2024

Ferroptosis, an iron-ion-dependent process of lipid peroxidation, damages the plasma membrane, leading to non-programmed cell death. Osteoarthritis (OA), a prevalent chronic degenerative joint disease among middle-aged and older adults, is characterized by chondrocyte damage or loss. Emerging evidence indicates that ferroptosis plays role in OA development. However, most research has concentrated on regulation involving typical iron ions, potentially neglecting significance elevated copper ions both serum fluid patients with OA. This review aims fill this gap systematically examining interplay between metabolism, oxidative stress, ferroptosis, copper-associated death It will provide comprehensive overview ions' regulating their dual approach seeks offer new insights for further research, prevention, treatment

Language: Английский

Recent Advancements in the Surface Modification of Additively Manufactured Metallic Bone Implants DOI Creative Commons

Jianhui Li,

Haitao Fan,

Hui Qiang Li

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown, P. 200195 - 200195

Published: Jan. 1, 2025

Language: Английский

Citations

2
Exploring Manufacturing Techniques in Bioceramic Scaffold Fabrication with a Focus on DIW 3D Printing for Tissue Engineering Applications DOI

B. Latha,

Ayyappan Susila Praveen,

M. Karthick

et al.

Annals of Biomedical Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: April 3, 2025

Language: Английский

Citations

0
Copper metabolism in osteoarthritis and its relation to oxidative stress and ferroptosis in chondrocytes DOI Creative Commons
Qingyuan Yu, Yanan Xiao, Mengqi Guan

et al.

Frontiers in Molecular Biosciences, Journal Year: 2024, Volume and Issue: 11

Published: Sept. 11, 2024

Ferroptosis, an iron-ion-dependent process of lipid peroxidation, damages the plasma membrane, leading to non-programmed cell death. Osteoarthritis (OA), a prevalent chronic degenerative joint disease among middle-aged and older adults, is characterized by chondrocyte damage or loss. Emerging evidence indicates that ferroptosis plays role in OA development. However, most research has concentrated on regulation involving typical iron ions, potentially neglecting significance elevated copper ions both serum fluid patients with OA. This review aims fill this gap systematically examining interplay between metabolism, oxidative stress, ferroptosis, copper-associated death It will provide comprehensive overview ions' regulating their dual approach seeks offer new insights for further research, prevention, treatment

Language: Английский

Citations

3