Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: unknown, P. 123656 - 123656
Published: April 1, 2025
Language: Английский
Materials Today Bio, Journal Year: 2025, Volume and Issue: 31, P. 101553 - 101553
Published: Feb. 5, 2025
Wounds infected by bacteria pose a considerable challenge in the field of healthcare, particularly with increasing prevalence antibiotic-resistant pathogens. Traditional antibiotics often fail to achieve effective results due limited penetration, resistance development, and inadequate local concentration at wound sites. These limitations necessitate exploration alternative strategies that can overcome drawbacks conventional therapies. Nanomaterials have emerged as promising solution for tackling bacterial infections facilitating healing, thanks their distinct physicochemical characteristics multifunctional capabilities. This review highlights latest developments nanomaterials demonstrated enhanced antibacterial efficacy improved healing outcomes. The mechanisms are varied, including ion release, chemodynamic therapy, photothermal/photodynamic electrostatic interactions, delivery drugs, which not only combat but also address challenges posed biofilms antibiotic resistance. Furthermore, these create an optimal environment tissue regeneration, promoting faster closure. By leveraging unique attributes nanomaterials, there is significant opportunity revolutionize management wounds markedly improve patient
Language: Английский
Citations
1
Journal of environmental chemical engineering, Journal Year: 2025, Volume and Issue: unknown, P. 116262 - 116262
Published: March 1, 2025
Language: Английский
Citations
1
Nanomaterials, Journal Year: 2025, Volume and Issue: 15(2), P. 111 - 111
Published: Jan. 13, 2025
The combination of molybdenum disulfide (MoS2) with plasmonic nanomaterials has opened up new possibilities in biological applications by combining MoS2’s biocompatibility and high surface area the optical sensitivity metals. These MoS2–plasmonic hybrid systems hold great promise areas such as biosensing, bioimaging, phototherapy, where their complementary properties facilitate improved detection, real-time visualization, targeted therapeutic interventions. adjustable features, combined plasmon resonance noble metals gold silver, enhance signal amplification, enabling detailed imaging selective photothermal or photodynamic therapies while minimizing effects on healthy tissue. This review explores various synthesis strategies for hybrids, including seed-mediated growth, situ deposition, heterojunction formation, which enable tailored configurations optimized specific applications. primary focus include highly sensitive biosensors detecting cancer infectious disease biomarkers, high-resolution cellular dynamics, development phototherapy methods that allow accurate tumor ablation through light-induced thermal reactive oxygen species generation. Despite promising advancements translating these platforms into clinical practice requires overcoming considerable challenges, reproducibility, toxicity, stability physiological conditions, delivery, scalable manufacturing. Addressing challenges is essential realizing potential next-generation tools diagnostics therapies.
Language: Английский
Citations
0
Advanced Science, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 25, 2025
Engineering hollow fibers with precise surface microstructures is challenging; yet, essential for guiding cells alignment and ensuring proper vascular tissue function. Inspired by Euplectella sponges, a novel strategy to engineer biomimetic spiral developed. Using oxidized bacterial cellulose, polydopamine, "brick-and-mortar" scaffold created through shear control during microfluidic coaxial spinning. The mimics natural extracellular matrices, providing mechanical stability supporting cell growth. In vitro studies show successful co-culture of endothelial (ECs) smooth muscle (SMCs), SMCs aligning along ECs forming confluent inner layer. vivo implantation confirms biocompatibility, biodegradability, low immunogenicity. This Euplectella-inspired presents promising approach engineering regenerative medicine.
Language: Английский
Citations
0
ACS Omega, Journal Year: 2025, Volume and Issue: unknown
Published: March 11, 2025
Hydrogels are highly versatile materials with immense potential for tissue engineering and regenerative medicine owing to their biocompatibility, tunable mechanical properties, ability mimic the natural extracellular matrix. Their 3D porous structure allows encapsulation delivery of bioactive molecules, making them ideal candidates drug systems. In repair, particularly bone regeneration, hydrogels can serve as carriers that release therapeutic agents in a controlled manner, thus enhancing healing process. Zeolitic Imidazolate Framework-8 (ZIF-8) nanoparticles recombinant human Bone Morphogenetic Protein (rhBMP-2) molecules were incorporated solely (ZIF@GelMA) or association (BMP@ZIF@GelMA) into gelatin modified by methacryloyl hydrogel (GelMA) investigate its physical osteogenic properties. characterized Scanning Electron Microscopy rheological tests. We analyzed degradation BSA profile BMP@ZIF@GelMA samples throughout 0, 1, 3, 7, 14, 28 days. Cell adhesion formation markers hydrogel-encapsulated dental pulp cells using immunocytochemistry molecular analysis. ZIF@GelMA exhibited viscoelastic increased storage modulus when rhBMP2 was present. BSA@ZIF@GelMA showed balanced rate BSA. The upregulated expression cell genes, BMP-2 introduced, levels remarkably elevated. presents several favorable factors promote cellular encouraging further prospects advanced applications repair.
Language: Английский
Citations
0
Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113517 - 113517
Published: March 1, 2025
Language: Английский
Citations
0
Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: unknown, P. 123656 - 123656
Published: April 1, 2025
Language: Английский
Citations
0