From Basic to Breakthroughs: The Journey of Microfluidic Devices in Hydrogel Droplet Generation DOI Creative Commons
Gabriela Hinojosa-Ventura, José Manuel Acosta-Cuevas, Carlos Arnulfo Velázquez-Carriles

et al.

Gels, Journal Year: 2025, Volume and Issue: 11(5), P. 309 - 309

Published: April 22, 2025

Hydrogel particles are essential in biological applications because of their distinctive capacity to retain water and encapsulate active molecules within three-dimensional structure. Typical particle sizes range from nanometers (10–500 nm) micrometers (1–500 µm), depending on the specific application method preparation. These characteristics render them optimal carriers for administration compounds, facilitating regulated prolonged release pharmaceuticals, including anticancer agents, antibiotics, therapeutic proteins. can exhibit various morphologies, spherical, rod-shaped, disk-shaped, core–shell structures. Each shape offers distinct advantages, such as improved circulation time, targeted drug delivery, or enhanced cellular uptake. Additionally, hydrogel be engineered respond stimuli, temperature, pH, light, magnetic fields, biochemical signals. Furthermore, biocompatibility acclimate many conditions make appropriate sophisticated applications, gene treatments, tissue regeneration, cell therapies. Microfluidics has transformed creation particles, providing precise control over dimensions, morphology, stability. This technique facilitates reproducible highly efficient production, reducing reagent waste optimizing encapsulation. The integration microfluidics with hydrogels provides opportunities advancement creative effective solutions contemporary medicine.

Language: Английский

From Basic to Breakthroughs: The Journey of Microfluidic Devices in Hydrogel Droplet Generation DOI Creative Commons
Gabriela Hinojosa-Ventura, José Manuel Acosta-Cuevas, Carlos Arnulfo Velázquez-Carriles

et al.

Gels, Journal Year: 2025, Volume and Issue: 11(5), P. 309 - 309

Published: April 22, 2025

Hydrogel particles are essential in biological applications because of their distinctive capacity to retain water and encapsulate active molecules within three-dimensional structure. Typical particle sizes range from nanometers (10–500 nm) micrometers (1–500 µm), depending on the specific application method preparation. These characteristics render them optimal carriers for administration compounds, facilitating regulated prolonged release pharmaceuticals, including anticancer agents, antibiotics, therapeutic proteins. can exhibit various morphologies, spherical, rod-shaped, disk-shaped, core–shell structures. Each shape offers distinct advantages, such as improved circulation time, targeted drug delivery, or enhanced cellular uptake. Additionally, hydrogel be engineered respond stimuli, temperature, pH, light, magnetic fields, biochemical signals. Furthermore, biocompatibility acclimate many conditions make appropriate sophisticated applications, gene treatments, tissue regeneration, cell therapies. Microfluidics has transformed creation particles, providing precise control over dimensions, morphology, stability. This technique facilitates reproducible highly efficient production, reducing reagent waste optimizing encapsulation. The integration microfluidics with hydrogels provides opportunities advancement creative effective solutions contemporary medicine.

Language: Английский

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