Cureus,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 1, 2024
Aim:
To
analyze
the
effect
of
bioactive
bone
cement
(BBC)
placed
in
a
phosphate
buffer
saline
solution
comparison
to
mineral
trioxide
aggregate
(MTA).
Methodology:
Ten
samples
each
BBC
(group
1)
and
MTA
2)
were
prepared
stored
solution.
After
three
days
storage,
white
precipitates
formed
on
surface
samples.
The
with
from
sample
was
analyzed
for
presence
calcium
ions
coupled
plasma
atomic
spectroscopy.
Results:
showed
significant
amount
release
after
seven-day
storage
period
Calcium
significantly
higher
group
1
(MTA)
(p
<
0.001)
compared
that
2
(BBC),
while
exhibited
greater
Conclusion:
retains
its
bioactivity
when
it
comes
into
contact
stimulated
oral
environment
(STF).
This
demonstrates
is
simulated
environment.
Moreover,
retained
good
handling
properties
could
be
easily
manipulated
dough
form.
Clinically,
cases
apical
surgery,
internal
resorption
or
perforation
repair
where
material
placement
poses
difficulty,
will
prove
beneficial.
RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(49), P. 36226 - 36245
Published: Jan. 1, 2024
Inflammatory
diseases
exert
a
significant
influence
on
the
periodontium,
serving
as
primary
contributor
to
development
of
periodontitis
and
alveolar
bone
loss.
ACS Biomaterials Science & Engineering,
Journal Year:
2024,
Volume and Issue:
10(2), P. 1077 - 1089
Published: Feb. 1, 2024
It
is
known
that
hydroxyapatite-type
calcium
phosphate
cement
(CPC)
shows
appreciable
self-curing
properties,
but
the
phase
transformation
products
often
lead
to
slow
biodegradation
and
disappointing
osteogenic
responses.
Herein,
we
developed
an
innovative
strategy
endow
invisible
micropore
networks,
which
could
tune
microstructures
of
α-tricalcium
(α-TCP)-based
CPC
by
gypsum
fibers,
capability
composite
cements
be
enhanced
in
vivo.
The
fibers
were
prepared
via
extruding
powder/carboxylated
chitosan
(CC)
slurry
through
a
22G
nozzle
(410
μm
diameter)
collecting
with
salt
solution.
Then,
CPCs
mixing
α-TCP
powder
(0–24
wt
%)
aqueous
solution
form
cements.
physicochemical
characterizations
showed
injectability
was
decreased
increase
fiber
contents.
μCT
reconstruction
demonstrated
distributed
substrate
produce
long-range
architectures.
In
particular,
incorporation
would
ion
release,
tunnel-like
pore
networks
vitro,
promote
new
bone
tissue
regeneration
rabbit
femoral
defects
Appropriate
(16
24
enhance
defect
repair
biodegradation.
These
results
demonstrate
highly
biodegradable
mediate
conventional
biomaterials,
such
bicomponent
may
beneficial
for
expanding
clinical
CPC-based
applications.
Pharmaceutics,
Journal Year:
2024,
Volume and Issue:
16(6), P. 754 - 754
Published: June 3, 2024
The
bioactive
surface
modification
of
implantable
devices
paves
the
way
towards
personalized
healthcare
practice
by
providing
a
versatile
and
tunable
approach
that
increase
patient
outcome,
facilitate
medical
procedure,
reduce
indirect
or
secondary
effects.
purpose
our
study
was
to
assess
performance
composite
coatings
based
on
biopolymeric
spheres
poly(lactide-co-glycolide)
embedded
with
hydroxyapatite
(HA)
methotrexate
(MTX).
Bio-simulated
tests
performed
for
up
one
week
evidenced
gradual
release
antitumor
drug
biomineralization
potential
PLGA/HA-MTX
sphere
coatings.
materials
proved
superior
biocompatibility
promoted
enhanced
cell
adhesion
proliferation
respect
human
preosteoblast
osteosarcoma
lines
when
compared
pristine
titanium.
