Recent Progress in the Development of Glucose Transporter (GLUT) Inhibitors
Yuxuan Wang,
No information about this author
Zhiqiang Sun,
No information about this author
Zean Zhao
No information about this author
et al.
Journal of Medicinal Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 2, 2025
Cancer
cells
exhibit
an
accelerated
glucose
uptake
and
glycolysis.
The
transmembrane
of
requires
specific
carrier
proteins,
such
as
transporters
(GLUTs)
sodium-coupled
cotransporters
(SGLTs).
GLUTs
transport
independently
the
energy
supply
have
become
promising
targets
for
cancer
therapy.
This
Perspective
mainly
focuses
on
current
research
progress
design
strategy
GLUT
inhibitors,
particularly
those
targeting
class
I
(GLUT1–4).
To
best
our
knowledge,
this
is
first
systematic
interpretation
progress,
opportunities,
challenges
faced
in
development
inhibitors
from
a
medicinal
chemistry
perspective.
We
hope
that
will
provide
insights
into
offering
feasible
approach
to
Language: Английский
Energy metabolism and spermatogenesis
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(19), P. e38591 - e38591
Published: Sept. 27, 2024
Language: Английский
The effect of partial replacement of calf fat and canola oil instead of dietary fish oil on growth performance, liver tissue, liver enzymes and chemical composition of young rainbow trout (Oncorhynchus mykiss)
Hamid Jafarnodeh,
No information about this author
Afshin Ghelichi,
No information about this author
S Jorjani
No information about this author
et al.
Aquaculture Reports,
Journal Year:
2024,
Volume and Issue:
36, P. 102097 - 102097
Published: April 24, 2024
Language: Английский
African walnut (Plukenetia conophora) oil promotes glucose uptake while improving energy metabolism and steroidogenesis and maintaining surface architecture in rat testes
Frontiers in Nutrition,
Journal Year:
2024,
Volume and Issue:
11
Published: Nov. 19, 2024
African
walnut
(
Language: Английский